Integrated proteomics and metabolomics analysis of D-pinitol function during hippocampal damage in streptozocin-induced aging-accelerated mice

A novel combination of sitagliptin and melatonin ameliorates T2D manifestations: studies on experimental diabetic models

(2023) R. Patel et al.   JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION

The role of cognitive rehabilitation in people with type 2 diabetes: A study protocol for a randomized controlled trial

(2023) Heather Cuevas et al.   PLoS One

Glycemic Variability in Patients with Type 2 Diabetes Mellitus (T2DM): The Role of Melatonin in a Crossover, Double-Blind, Placebo-Controlled, Randomized Study

(2023) Wagner Martorina et al.   Nutrients

Therapeutic effect of melatonin-loaded chitosan/lecithin nanoparticles on hyperglycemia and pancreatic beta cells regeneration in streptozotocin-induced diabetic rats

(2023) Habiba Alaa et al.   Scientific Reports

Predictor of cognitive impairment: metabolic syndrome or circadian syndrome

(2023) Yang Liu et al.   BMC Geriatrics

Caveolin-1 Alleviates Diabetes-Associated Cognitive Dysfunction Through Modulating Neuronal Ferroptosis-Mediated Mitochondrial Homeostasis

(2022) Wenxin Tang et al.   ANTIOXIDANTS & REDOX SIGNALING

Label-free in vivo assessment of brain mitochondrial redox states during the development of diabetic cognitive impairment using Raman spectroscopy

(2022) Meiyan Wu et al.   FREE RADICAL BIOLOGY AND MEDICINE

D-Pinitol—Active Natural Product from Carob with Notable Insulin Regulation

(2022) Abdullatif Azab   Nutrients

Pharmacological effects of D‐Pinitol – A comprehensive review

(2022) Anandakumar Pandi et al.   JOURNAL OF FOOD BIOCHEMISTRY

Inside the diabetic brain: Insulin resistance and molecular mechanism associated with cognitive impairment and its possible therapeutic strategies

(2022) Bhaskar Jyoti Dutta et al.   PHARMACOLOGICAL RESEARCH

Molecular mechanisms underlying hyperglycemia associated cognitive decline

(2022) Mrinal Gupta et al.   IBRO Neuroscience Reports

Comprehensive metabolic profiling of Parkinson’s disease by liquid chromatography-mass spectrometry

(2021) Yaping Shao et al.   Molecular Neurodegeneration

Protective mechanism of Syringic acid in an experimental model of Parkinson’s disease

(2021) Özge Güzelad et al.   METABOLIC BRAIN DISEASE

Profilin2 regulates actin rod assembly in neuronal cells

(2021) Lisa Marie Walter et al.   Scientific Reports

Long‐term plasticity in the hippocampus: maintaining within and ‘tagging’ between synapses

(2021) Mohammad Zaki Bin Ibrahim et al.   FEBS Journal

The interplay among oxidative stress, brain insulin resistance and AMPK dysfunction contribute to neurodegeneration in type 2 diabetes and Alzheimer disease

(2021) Eugenio Barone et al.   FREE RADICAL BIOLOGY AND MEDICINE

Effects of Black Garlic Extract and Nanoemulsion on the Deoxy Corticosterone Acetate-Salt Induced Hypertension and Its Associated Mild Cognitive Impairment in Rats

(2021) Chun-Yu Chen et al.   Antioxidants

Protective effect of D-pinitol on the experimental spinal cord injury in rats

(2020) Yan An et al.   METABOLIC BRAIN DISEASE

Pinitol Prevents Lipopolysaccharide (LPS)-Induced Inflammatory Responses in BV2 Microglia Mediated by TREM2

(2020) Juan Kong et al.   NEUROTOXICITY RESEARCH

Protective effects of diallyl trisulfide (DATS) against doxorubicin-induced inflammation and oxidative stress in the brain of rats

(2020) Wai-Shing Leung et al.   FREE RADICAL BIOLOGY AND MEDICINE

The influence of syringic acid treatment on total dopamine levels of the hippocampus and on cognitive behavioral skills

(2020) Eren Ogut et al.   INTERNATIONAL JOURNAL OF NEUROSCIENCE

Presynaptic Vesicle Protein SEPTIN5 Regulates the Degradation of APP C-Terminal Fragments and the Levels of Aβ

(2020) Mikael Marttinen et al.   Cells

18F-FDG-PET Detects Drastic Changes in Brain Metabolism in the Tg4–42 Model of Alzheimer’s Disease

(2019) Caroline Bouter et al.   Frontiers in Aging Neuroscience

Age- and AD-related redox state of NADH in subcellular compartments by fluorescence lifetime imaging microscopy

(2019) Yue Dong et al.   GeroScience

Neuropharmacological effects of d ‐pinitol and its possible mechanisms of action

(2019) Angel Josabad Alonso‐Castro et al.   JOURNAL OF FOOD BIOCHEMISTRY

Secernin-1 is a novel phosphorylated tau binding protein that accumulates in Alzheimer’s disease and not in other tauopathies

(2019) Geoffrey Pires et al.   Acta Neuropathologica Communications

Syringic acid, a phenolic acid, promotes osteoblast differentiation by stimulation of Runx2 expression and targeting of Smad7 by miR-21 in mouse mesenchymal stem cells

(2018) B. Arumugam et al.   Journal of Cell Communication and Signaling

Diallyl Trisulfide Protects Motor Neurons from the Neurotoxic Protein TDP-43 via Activating Lysosomal Degradation and the Antioxidant Response

(2018) Chang Liu et al.   NEUROCHEMICAL RESEARCH

Global aetiology and epidemiology of type 2 diabetes mellitus and its complications

(2017) Yan Zheng et al.   Nature Reviews Endocrinology

Spatial memory impairment in Morris water maze after electroconvulsive seizures

(2016) Maria Svensson et al.   ACTA NEUROPSYCHIATRICA

Proteins that mediate protein aggregation and cytotoxicity distinguish Alzheimer's hippocampus from normal controls

(2016) Srinivas Ayyadevara et al.   AGING CELL

The calcium sensor Copine-6 regulates spine structural plasticity and learning and memory

(2016) Judith R. Reinhard et al.   Nature Communications

Spatial memory impairment in Morris water maze after electroconvulsive seizures

(2016) Maria Svensson et al.   ACTA NEUROPSYCHIATRICA

Tissue-based map of the human proteome

(2015) M. Uhlen et al.   SCIENCE

Spatial and Working Memory Is Linked to Spine Density and Mushroom Spines

(2015) Rasha Refaat Mahmmoud et al.   PLoS One

Short-term melatonin consumption protects the heart of obese rats independent of body weight change and visceral adiposity

(2014) Frederic Nduhirabandi et al.   JOURNAL OF PINEAL RESEARCH

Quantitative accuracy in mass spectrometry based proteomics of complex samples: The impact of labeling and precursor interference

(2013) AnnSofi Sandberg et al.   Journal of Proteomics

The Veratrum alkaloids jervine, veratramine, and their analogues as prostate cancer migration and proliferation inhibitors: biological evaluation and pharmacophore modeling

(2013) Mohammed A. Khanfar et al.   MEDICINAL CHEMISTRY RESEARCH

Analysis of the Human Tissue-specific Expression by Genome-wide Integration of Transcriptomics and Antibody-based Proteomics

(2013) Linn Fagerberg et al.   MOLECULAR & CELLULAR PROTEOMICS

Proteomic profiling of brain cortex tissues in a Tau transgenic mouse model of Alzheimer’s disease

(2012) Seong-Hun Chang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Oxidative Damage Compromises Energy Metabolism in the Axonal Degeneration Mouse Model of X-Adrenoleukodystrophy

(2011) Jorge Galino et al.   ANTIOXIDANTS & REDOX SIGNALING

Association of cognitive dysfunction with hippocampal atrophy in elderly Japanese people with type 2 diabetes

(2011) Kumi Hayashi et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

Septin filaments exhibit a dynamic, paired organization that is conserved from yeast to mammals

(2011) Bradley S. DeMay et al.   JOURNAL OF CELL BIOLOGY

Conquering the complex world of human septins: implications for health and disease

(2010) EA Peterson et al.   CLINICAL GENETICS

Copines-1, -2, -3, -6 and -7 show different calcium-dependent intracellular membrane translocation and targeting

(2010) Pavel V. Perestenko et al.   FEBS Journal

Universal sample preparation method for proteome analysis

(2009) Jacek R Wiśniewski et al.   NATURE METHODS

Increased melatonin synthesis in pineal glands of rats in streptozotocin induced type 1 diabetes

(2008) Elmar Peschke et al.   JOURNAL OF PINEAL RESEARCH