Secernin-1 is a novel phosphorylated tau binding protein that accumulates in Alzheimer’s disease and not in other tauopathies

Dementia in Down syndrome: unique insights for Alzheimer disease research

(2019) Ira T. Lott et al.   Nature Reviews Neurology

Single-cell transcriptomic analysis of Alzheimer’s disease

(2019) Hansruedi Mathys et al.   NATURE

Four-repeat tauopathies

(2019) Thomas W. Rösler et al.   PROGRESS IN NEUROBIOLOGY

VAP‐SCRN1 interaction regulates dynamic endoplasmic reticulum remodeling and presynaptic function

(2019) Feline W Lindhout et al.   EMBO JOURNAL

Tau-Mediated Disruption of the Spliceosome Triggers Cryptic RNA Splicing and Neurodegeneration in Alzheimer’s Disease

(2019) Yi-Chen Hsieh et al.   Cell Reports

Aging-related tau astrogliopathy (ARTAG): not only tau phosphorylation in astrocytes

(2018) Isidro Ferrer et al.   BRAIN PATHOLOGY

Tau filaments in neurodegenerative diseases

(2018) Michel Goedert   FEBS LETTERS

Potential Novel Approaches to Understand the Pathogenesis and Treat Alzheimer’s Disease

(2018) Eleanor Drummond et al.   JOURNAL OF ALZHEIMERS DISEASE

Tau Proteolysis in the Pathogenesis of Tauopathies: Neurotoxic Fragments and Novel Biomarkers

(2018) James P. Quinn et al.   JOURNAL OF ALZHEIMERS DISEASE

Whole transcriptome profiling of Late-Onset Alzheimer’s Disease patients provides insights into the molecular changes involved in the disease

(2018) Anita Annese et al.   Scientific Reports

Global quantitative analysis of the human brain proteome in Alzheimer’s and Parkinson’s Disease

(2018) Lingyan Ping et al.   Scientific Data

Structures of filaments from Pick’s disease reveal a novel tau protein fold

(2018) Benjamin Falcon et al.   NATURE

Tau filaments from multiple cases of sporadic and inherited Alzheimer’s disease adopt a common fold

(2018) Benjamin Falcon et al.   ACTA NEUROPATHOLOGICA

Deep proteomic network analysis of Alzheimer’s disease brain reveals alterations in RNA binding proteins and RNA splicing associated with disease

(2018) Erik C. B. Johnson et al.   Molecular Neurodegeneration

Different tau species lead to heterogeneous tau pathology propagation and misfolding

(2018) Simon Dujardin et al.   Acta Neuropathologica Communications

Alzheimer's disease

(2017) C. A. Lane et al.   EUROPEAN JOURNAL OF NEUROLOGY

Neurodegeneration: Taming tangled tau

(2017) David S. Eisenberg et al.   NATURE

Cryo-EM structures of tau filaments from Alzheimer’s disease

(2017) Anthony W. P. Fitzpatrick et al.   NATURE

Structure-based inhibitors of tau aggregation

(2017) P. M. Seidler et al.   Nature Chemistry

The use of localized proteomics to identify the drivers of Alzheimer's disease pathogenesis

(2017) Eleanor Drummond et al.   Neural Regeneration Research

A Multi-network Approach Identifies Protein-Specific Co-expression in Asymptomatic and Symptomatic Alzheimer’s Disease

(2017) Nicholas T. Seyfried et al.   Cell Systems

RAGE and Alzheimer's Disease: A Progression Factor for Amyloid-β-Induced Cellular Perturbation?

(2017) Shi Du Yan et al.   JOURNAL OF ALZHEIMERS DISEASE

Proteins that mediate protein aggregation and cytotoxicity distinguish Alzheimer's hippocampus from normal controls

(2016) Srinivas Ayyadevara et al.   AGING CELL

Caspase-2 cleavage of tau reversibly impairs memory

(2016) Xiaohui Zhao et al.   NATURE MEDICINE

Tauopathies as clinicopathological entities

(2016) David J. Irwin   PARKINSONISM & RELATED DISORDERS

PART is part of Alzheimer disease

(2015) Charles Duyckaerts et al.   ACTA NEUROPATHOLOGICA

Aging-related tau astrogliopathy (ARTAG): harmonized evaluation strategy

(2015) Gabor G. Kovacs et al.   ACTA NEUROPATHOLOGICA

Down syndrome and Alzheimer's disease: Common pathways, common goals

(2015) Dean Hartley et al.   Alzheimers & Dementia

Secernin-1 Contributes to Colon Cancer Progression through Enhancing Matrix Metalloproteinase-2/9 Exocytosis

(2015) Shengtao Lin et al.   DISEASE MARKERS

Tissue-based map of the human proteome

(2015) M. Uhlen et al.   SCIENCE

Proteomic analysis of neurons microdissected from formalin-fixed, paraffin-embedded Alzheimer’s disease brain tissue

(2015) Eleanor S Drummond et al.   Scientific Reports

Primary age-related tauopathy (PART): a common pathology associated with human aging

(2014) John F. Crary et al.   ACTA NEUROPATHOLOGICA

Cleavage of tau by asparagine endopeptidase mediates the neurofibrillary pathology in Alzheimer's disease

(2014) Zhentao Zhang et al.   NATURE MEDICINE

A C69-family cysteine dipeptidase from Lactobacillus farciminis JCM1097 possesses strong Gly-Pro hydrolytic activity

(2013) T. Sakamoto et al.   JOURNAL OF BIOCHEMISTRY

Analysis of the Human Tissue-specific Expression by Genome-wide Integration of Transcriptomics and Antibody-based Proteomics

(2013) Linn Fagerberg et al.   MOLECULAR & CELLULAR PROTEOMICS

The Genotype-Tissue Expression (GTEx) project

(2013) John Lonsdale et al.   NATURE GENETICS

Proteomic profiling of brain cortex tissues in a Tau transgenic mouse model of Alzheimer’s disease

(2012) Seong-Hun Chang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

National Institute on Aging–Alzheimer’s Association guidelines for the neuropathologic assessment of Alzheimer’s disease: a practical approach

(2011) Thomas J. Montine et al.   ACTA NEUROPATHOLOGICA

Unknown

(2011) Adriana Ferreira et al.   MOLECULAR MEDICINE

Tau in Alzheimer Disease and Related Tauopathies

(2010) K. Iqbal et al.   Current Alzheimer Research

Three- and Four-repeat Tau Coassemble into Heterogeneous Filaments

(2010) Ayisha Siddiqua et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Classification and basic pathology of Alzheimer disease

(2009) Charles Duyckaerts et al.   ACTA NEUROPATHOLOGICA

Signaling effect of amyloid-β42 on the processing of AβPP

(2009) Massimo Tabaton et al.   EXPERIMENTAL NEUROLOGY

Tau fragmentation, aggregation and clearance: the dual role of lysosomal processing

(2009) Yipeng Wang et al.   HUMAN MOLECULAR GENETICS

TrkA pathway activation induced by amyloid-beta (Abeta)

(2008) Alessandra Bulbarelli et al.   MOLECULAR AND CELLULAR NEUROSCIENCE