Long‐term plasticity in the hippocampus: maintaining within and ‘tagging’ between synapses

Age‐related changes in hippocampal‐dependent synaptic plasticity and memory mediated by p75 neurotrophin receptor

(2021) Lik‐Wei Wong et al.   AGING CELL

Crucial role for CA2 inputs in the sequential organization of CA1 time cells supporting memory

(2021) Christopher J. MacDonald et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Immediate Early Gene Arc Is Not Required for Hippocampal Long-Term Potentiation

(2021) Madeleine Kyrke-Smith et al.   JOURNAL OF NEUROSCIENCE

Posterior basolateral amygdala to ventral hippocampal CA1 drives approach behaviour to exert an anxiolytic effect

(2020) Guilin Pi et al.   Nature Communications

Inhibition of Histone Deacetylase Reinstates Hippocampus-Dependent Long-Term Synaptic Plasticity and Associative Memory in Sleep-Deprived Mice

(2020) Lik-Wei Wong et al.   CEREBRAL CORTEX

Two functionally distinct serotonergic projections into hippocampus

(2020) Alessandro Luchetti et al.   JOURNAL OF NEUROSCIENCE

IQGAP1/ERK regulates fear memory formation via histone posttranslational modifications induced by HDAC2

(2020) Xiao-Ya Liu et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Group III metabotropic glutamate receptors gate long-term potentiation and synaptic tagging/capture in rat hippocampal area CA2

(2020) Ananya Dasgupta et al.   eLife

Regulation of aberrant proteasome activity re‐establishes plasticity and long‐term memory in an animal model of Alzheimer's disease

(2020) Kumar Krishna‐K et al.   FASEB JOURNAL

Exposure to Novelty Promotes Long-Term Contextual Fear Memory Formation in Juvenile Mice: Evidence for a Behavioral Tagging

(2020) Ning Chen et al.   MOLECULAR NEUROBIOLOGY

Behavioral tagging underlies memory reconsolidation

(2020) Iván Rabinovich Orlandi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Selective neuromodulation and mutual inhibition within the CA3–CA2 system can prioritize sequences for replay

(2020) Tristan M. Stöber et al.   HIPPOCAMPUS

A hypothalamic novelty signal modulates hippocampal memory

(2020) Shuo Chen et al.   NATURE

Neuronal Activity at Synapse Resolution: Reporters and Effectors for Synaptic Neuroscience

(2020) Francesco Gobbo et al.   Frontiers in Molecular Neuroscience

Long-term population spike-timing-dependent plasticity promotes synaptic tagging but not cross-tagging in rat hippocampal area CA1

(2019) Karen Ka Lam Pang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Epigenetics and memory: Emerging role of histone lysine methyltransferase G9a/GLP complex as bidirectional regulator of synaptic plasticity

(2019) Karen Ka Lam Pang et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

The p75 neurotrophin receptor is an essential mediator of impairments in hippocampal-dependent associative plasticity and memory induced by sleep deprivation

(2019) Lik-Wei Wong et al.   JOURNAL OF NEUROSCIENCE

PKM-ζ Expression Is Important in Consolidation of Memory in Prelimbic Cortex Formed by the Process of Behavioral Tagging

(2019) Mehar Naseem et al.   NEUROSCIENCE

Modulation of CA2 neuronal activity increases behavioral responses to fear conditioning in female mice

(2019) Georgia M. Alexander et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

The MK2 cascade regulates mGluR-dependent synaptic plasticity and reversal learning

(2019) Lucia Privitera et al.   NEUROPHARMACOLOGY

MicroRNA‐134‐5p inhibition rescues long‐term plasticity and synaptic tagging/capture in an Aβ(1–42)‐induced model of Alzheimer’s disease

(2019) Nimmi Baby et al.   AGING CELL

Pharmacological Inhibition of G9a/GLP restores cognition and reduces oxidative stress, neuroinflammation and β-Amyloid plaques in an early-onset Alzheimer’s disease mouse model

(2019) Christian Griñán-Ferré et al.   Aging-US

Complex neuroprotective and neurotoxic effects of histone deacetylases

(2018) Elizabeth A. Thomas et al.   JOURNAL OF NEUROCHEMISTRY

Long-term potentiation in the hippocampus: discovery, mechanisms and function

(2018) Tim V.P. Bliss et al.   Neuroforum

Hippocampal 5-HT Input Regulates Memory Formation and Schaffer Collateral Excitation

(2018) Catia M. Teixeira et al.   NEURON

The role of 19S proteasome associated deubiquitinases in activity-dependent hippocampal synaptic plasticity

(2018) Di Yun et al.   NEUROPHARMACOLOGY

Behavioral Tagging: Plausible involvement of PKMζ, Arc and role of neurotransmitter receptor systems

(2018) Shruti Vishnoi et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Interregional synaptic maps among engram cells underlie memory formation

(2018) Jun-Hyeok Choi et al.   SCIENCE

Synapse-specific representation of the identity of overlapping memory engrams

(2018) Kareem Abdou et al.   SCIENCE

Hippocampal area CA2: an emerging modulatory gateway in the hippocampal circuit

(2018) Amrita Benoy et al.   EXPERIMENTAL BRAIN RESEARCH

Regulation of synaptic plasticity in hippocampal area CA2

(2018) Kelly E Carstens et al.   CURRENT OPINION IN NEUROBIOLOGY

Oxytocin Transforms Firing Mode of CA2 Hippocampal Neurons

(2018) Natasha N. Tirko et al.   NEURON

Novelty and Dopaminergic Modulation of Memory Persistence: A Tale of Two Systems

(2018) Adrian J. Duszkiewicz et al.   TRENDS IN NEUROSCIENCES

A hippocampal circuit linking dorsal CA2 to ventral CA1 critical for social memory dynamics

(2018) Torcato Meira et al.   Nature Communications

CA2 neuronal activity controls hippocampal low gamma and ripple oscillations

(2018) Georgia M Alexander et al.   eLife

Neuromodulation of hippocampal long-term synaptic plasticity

(2018) Jon Palacios-Filardo et al.   CURRENT OPINION IN NEUROBIOLOGY

Hippocampal LTP and contextual learning require surface diffusion of AMPA receptors

(2017) A. C. Penn et al.   NATURE

Differential involvement of Ca2+/calmodulin-dependent protein kinases and mitogen-activated protein kinases in the dopamine D1/D5 receptor-mediated potentiation in hippocampal CA1 pyramidal neurons

(2017) Mahesh Shivarama Shetty et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Activity-dependent synapse to nucleus signaling

(2017) Agnes Fang Yi Lim et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Locus coeruleus input to hippocampal CA3 drives single-trial learning of a novel context

(2017) Akiko Wagatsuma et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Metaplasticity mechanisms restore plasticity and associativity in an animal model of Alzheimer’s disease

(2017) Qin Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Substance P induces plasticity and synaptic tagging/capture in rat hippocampal area CA2

(2017) Ananya Dasgupta et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The genetics of PKMζ and memory maintenance

(2017) Todd Charlton Sacktor et al.   Science Signaling

The genetics of PKMζ and memory maintenance

(2017) Todd Charlton Sacktor et al.   Science Signaling

Chelation of hippocampal zinc enhances long-term potentiation and synaptic tagging/capture in CA1 pyramidal neurons of aged rats: implications to aging and memory

(2016) Mahesh Shivarama Shetty et al.   AGING CELL

Inhibition of Histone Deacetylase 3 Restores Amyloid-β Oligomer-Induced Plasticity Deficit in Hippocampal CA1 Pyramidal Neurons

(2016) Kumar Krishna et al.   JOURNAL OF ALZHEIMERS DISEASE

Targeted activation of the hippocampal CA2 area strongly enhances social memory

(2016) A S Smith et al.   MOLECULAR PSYCHIATRY

A shared neural ensemble links distinct contextual memories encoded close in time

(2016) Denise J. Cai et al.   NATURE

Locus coeruleus and dopaminergic consolidation of everyday memory

(2016) Tomonori Takeuchi et al.   NATURE

Behavioral tagging: A novel model for studying long-term memory

(2016) Shruti Vishnoi et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Dopamine release from the locus coeruleus to the dorsal hippocampus promotes spatial learning and memory

(2016) Kimberly A. Kempadoo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Social and novel contexts modify hippocampal CA2 representations of space

(2016) Georgia M. Alexander et al.   Nature Communications

Forget me not

(2016) Richard GM Morris   eLife

Compensation for PKMζ in long-term potentiation and spatial long-term memory in mutant mice

(2016) Panayiotis Tsokas et al.   eLife

Forgetting of long-term memory requires activation of NMDA receptors, L-type voltage-dependent Ca2+ channels, and calcineurin

(2016) Ricardo Marcelo Sachser et al.   Scientific Reports

Ubiquitin-Proteasome System Inhibition Promotes Long-Term Depression and Synaptic Tagging/Capture

(2015) Qin Li et al.   CEREBRAL CORTEX

Dopamine D1/D5 receptor signaling regulates synaptic cooperation and competition in hippocampal CA1 pyramidal neurons via sustained ERK1/2 activation

(2015) Mahesh Shivarama Shetty et al.   HIPPOCAMPUS

Pronounced differences in signal processing and synaptic plasticity between piriform-hippocampal network stages: a prominent role for adenosine

(2015) Brian H. Trieu et al.   JOURNAL OF PHYSIOLOGY-LONDON

From the neuron doctrine to neural networks

(2015) Rafael Yuste   NATURE REVIEWS NEUROSCIENCE

BDNF pro-peptide actions facilitate hippocampal LTD and are altered by the common BDNF polymorphism Val66Met

(2015) Toshiyuki Mizui et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Histone deacetylase 3 inhibition re-establishes synaptic tagging and capture in aging through the activation of nuclear factor kappa B

(2015) Mahima Sharma et al.   Scientific Reports

Lesions to the CA2 region of the hippocampus impair social memory in mice

(2014) Erica L. Stevenson et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Assessing Spatial Learning and Memory in Rodents

(2014) C. V. Vorhees et al.   ILAR JOURNAL

Long-term potentiation decay and memory loss are mediated by AMPAR endocytosis

(2014) Zhifang Dong et al.   JOURNAL OF CLINICAL INVESTIGATION

NMDA Receptor-Dependent LTD Is Required for Consolidation But Not Acquisition of Fear Memory

(2014) X. Liu et al.   JOURNAL OF NEUROSCIENCE

Role of the vasopressin 1b receptor in rodent aggressive behavior and synaptic plasticity in hippocampal area CA2

(2014) J H Pagani et al.   MOLECULAR PSYCHIATRY

The hippocampal CA2 region is essential for social memory

(2014) Frederick L. Hitti et al.   NATURE

Engineering a memory with LTD and LTP

(2014) Sadegh Nabavi et al.   NATURE

Synaptic tagging during memory allocation

(2014) Thomas Rogerson et al.   NATURE REVIEWS NEUROSCIENCE

Neurons Are Recruited to a Memory Trace Based on Relative Neuronal Excitability Immediately before Training

(2014) Adelaide P. Yiu et al.   NEURON

Competition between recently potentiated synaptic inputs reveals a winner-take-all phase of synaptic tagging and capture

(2014) S. Sajikumar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cognitive flexibility and long-term depression (LTD) are impaired following  -catenin stabilization in vivo

(2014) F. Mills et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

proBDNF Negatively Regulates Neuronal Remodeling, Synaptic Transmission, and Synaptic Plasticity in Hippocampus

(2014) Jianmin Yang et al.   Cell Reports

N-methyl-d-aspartate receptors, learning and memory: chronic intraventricular infusion of the NMDA receptor antagonistd-AP5 interacts directly with the neural mechanisms of spatial learning

(2013) R. G. M. Morris et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

The interplay between Hebbian and homeostatic synaptic plasticity

(2013) Nathalia Vitureira et al.   JOURNAL OF CELL BIOLOGY

Prkcz null mice show normal learning and memory

(2013) Anna M. Lee et al.   NATURE

PKM-ζ is not required for hippocampal synaptic plasticity, learning and memory

(2013) Lenora J. Volk et al.   NATURE

Reactivation enables memory updating, precision-keeping and strengthening: Exploring the possible biological roles of reconsolidation

(2013) L. De Oliveira Alvares et al.   NEUROSCIENCE

The Histone Deacetylase HDAC4 Regulates Long-Term Memory in Drosophila

(2013) Helen L. Fitzsimons et al.   PLoS One

Behavioral tagging of extinction learning

(2013) J. de Carvalho Myskiw et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

HDAC4 Governs a Transcriptional Program Essential for Synaptic Plasticity and Memory

(2012) Richard Sando et al.   CELL

Activity-Dependent Transport of the Transcriptional Coactivator CRTC1 from Synapse to Nucleus

(2012) Toh Hean Ch'ng et al.   CELL

Making Synapses Strong: Metaplasticity Prolongs Associativity of Long-Term Memory by Switching Synaptic Tag Mechanisms

(2012) Qin Li et al.   CEREBRAL CORTEX

Dopamine D1/D5 Receptors Mediate Informational Saliency that Promotes Persistent Hippocampal Long-Term Plasticity

(2012) N. Hansen et al.   CEREBRAL CORTEX

Activity-dependent actin dynamics are required for the maintenance of long-term plasticity and for synaptic capture

(2012) Rosalina Fonseca   EUROPEAN JOURNAL OF NEUROSCIENCE

Endogenous hippocampal LTD that is enabled by spatial object recognition requires activation of NMDA receptors and the metabotropic glutamate receptor, mGlu5

(2012) Jinzhong Jeremy Goh et al.   HIPPOCAMPUS

G9a/GLP Histone Lysine Dimethyltransferase Complex Activity in the Hippocampus and the Entorhinal Cortex Is Required for Gene Activation and Silencing during Memory Consolidation

(2012) S. Gupta-Agarwal et al.   JOURNAL OF NEUROSCIENCE

Dopamine induces LTP differentially in apical and basal dendrites through BDNF and voltage-dependent calcium channels

(2012) S. Navakkode et al.   LEARNING & MEMORY

Mechanisms of CaMKII action in long-term potentiation

(2012) John Lisman et al.   NATURE REVIEWS NEUROSCIENCE

Role of metabotropic glutamate receptors in persistent forms of hippocampal plasticity and learning

(2012) Sreedeep Mukherjee et al.   NEUROPHARMACOLOGY

Novelty exposure overcomes foot shock-induced spatial-memory impairment by processes of synaptic-tagging in rats

(2012) W. Almaguer-Melian et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

NMDA Receptor-Dependent Long-Term Potentiation and Long-Term Depression (LTP/LTD)

(2012) C. Luscher et al.   Cold Spring Harbor Perspectives in Biology

Synaptic tagging and capture in the living rat

(2012) K.L. Shires et al.   Nature Communications

Catching the engram: strategies to examine the memory trace

(2012) Masanori Sakaguchi et al.   Molecular Brain

Molecular Constraints on Synaptic Tagging and Maintenance of Long-Term Potentiation: A Predictive Model

(2012) Paul Smolen et al.   PLoS Computational Biology

Posttranslational regulation of AMPA receptor trafficking and function

(2011) Wei Lu et al.   CURRENT OPINION IN NEUROBIOLOGY

MicroRNA regulation of neural plasticity and memory

(2011) Timothy W. Bredy et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Nonapoptotic Function of BAD and BAX in Long-Term Depression of Synaptic Transmission

(2011) Song Jiao et al.   NEURON

The Dendritic Branch Is the Preferred Integrative Unit for Protein Synthesis-Dependent LTP

(2011) Arvind Govindarajan et al.   NEURON

Activity Dependent Protein Degradation Is Critical for the Formation and Stability of Fear Memory in the Amygdala

(2011) Timothy J. Jarome et al.   PLoS One

Metaplasticity governs compartmentalization of synaptic tagging and capture through brain-derived neurotrophic factor (BDNF) and protein kinase M  (PKM )

(2011) S. Sajikumar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of transmitter systems and learning tag molecules involved in behavioral tagging during memory formation

(2011) D. Moncada et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Memory Reconsolidation Mediates the Updating of Hippocampal Memory Content

(2011) Jonathan L. C. Lee   Frontiers in Behavioral Neuroscience

Caspase-3 Activation via Mitochondria Is Required for Long-Term Depression and AMPA Receptor Internalization

(2010) Zheng Li et al.   CELL

Autophosphorylated CaMKIIα Acts as a Scaffold to Recruit Proteasomes to Dendritic Spines

(2010) Baris Bingol et al.   CELL

Synaptic Tagging and Capture: Differential Role of Distinct Calcium/Calmodulin Kinases in Protein Synthesis-Dependent Long-Term Potentiation

(2010) R. L. Redondo et al.   JOURNAL OF NEUROSCIENCE

Protein kinase M  is essential for the induction and maintenance of dopamine-induced long-term potentiation in apical CA1 dendrites

(2010) S. Navakkode et al.   LEARNING & MEMORY

In situ visualization and dynamics of newly synthesized proteins in rat hippocampal neurons

(2010) Daniela C Dieterich et al.   NATURE NEUROSCIENCE

Long-term depression in the CNS

(2010) Graham L. Collingridge et al.   NATURE REVIEWS NEUROSCIENCE

Making memories last: the synaptic tagging and capture hypothesis

(2010) Roger L. Redondo et al.   NATURE REVIEWS NEUROSCIENCE

Group 1 mGluR-Dependent Synaptic Long-Term Depression: Mechanisms and Implications for Circuitry and Disease

(2010) Christian Lüscher et al.   NEURON

Strong CA2 Pyramidal Neuron Synapses Define a Powerful Disynaptic Cortico-Hippocampal Loop

(2010) Vivien Chevaleyre et al.   NEURON

Arc regulates spine morphology and maintains network stability in vivo

(2010) C. L. Peebles et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Relevance of synaptic tagging and capture to the persistence of long-term potentiation and everyday spatial memory

(2010) S.-H. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Spatially restricting gene expression by local translation at synapses

(2010) Dan Ohtan Wang et al.   TRENDS IN NEUROSCIENCES

Locus Coeruleus Activation Facilitates Memory Encoding and Induces Hippocampal LTD that Depends on  -Adrenergic Receptor Activation

(2009) N. Lemon et al.   CEREBRAL CORTEX

Regulation of the Proteasome by Neuronal Activity and Calcium/Calmodulin-dependent Protein Kinase II

(2009) Stevan N. Djakovic et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Roles of CaMKII and F-Actin in the Structural Plasticity of Dendritic Spines: A Potential Molecular Identity of a Synaptic Tag?

(2009) Kenichi Okamoto et al.   PHYSIOLOGY

Behavioral tagging is a general mechanism of long-term memory formation

(2009) F. Ballarini et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Input-Specific Spine Entry of Soma-Derived Vesl-1S Protein Conforms to Synaptic Tagging

(2009) D. Okada et al.   SCIENCE

Dopamine Controls Persistence of Long-Term Memory Storage

(2009) J. I. Rossato et al.   SCIENCE

PKM  Maintains Late Long-Term Potentiation by N-Ethylmaleimide-Sensitive Factor/GluR2-Dependent Trafficking of Postsynaptic AMPA Receptors

(2008) Y. Yao et al.   JOURNAL OF NEUROSCIENCE

The Tyrosine Phosphatase STEP Mediates AMPA Receptor Endocytosis after Metabotropic Glutamate Receptor Stimulation

(2008) Y. Zhang et al.   JOURNAL OF NEUROSCIENCE

Transgenic Mice Lacking NMDAR-Dependent LTD Exhibit Deficits in Behavioral Flexibility

(2008) Russell E. Nicholls et al.   NEURON

Understanding Synapses: Past, Present, and Future

(2008) Thomas C. Südhof et al.   NEURON

Elongation Factor 2 and Fragile X Mental Retardation Protein Control the Dynamic Translation of Arc/Arg3.1 Essential for mGluR-LTD

(2008) Sungjin Park et al.   NEURON

Rapid Translation of Arc/Arg3.1 Selectively Mediates mGluR-Dependent LTD through Persistent Increases in AMPAR Endocytosis Rate

(2008) Maggie W. Waung et al.   NEURON

Synaptic Protein Degradation Underlies Destabilization of Retrieved Fear Memory

(2008) S.-H. Lee et al.   SCIENCE

Protein Synthesis and Neurotrophin-Dependent Structural Plasticity of Single Dendritic Spines

(2008) J.-i. Tanaka et al.   SCIENCE

PKMζ Maintains Spatial, Instrumental, and Classically Conditioned Long-Term Memories

(2008) Peter Serrano et al.   PLOS BIOLOGY

Tag-Trigger-Consolidation: A Model of Early and Late Long-Term-Potentiation and Depression

(2008) Claudia Clopath et al.   PLoS Computational Biology

LTP maintenance and its protein synthesis-dependence

(2007) Wickliffe C. Abraham et al.   NEUROBIOLOGY OF LEARNING AND MEMORY