Pinitol Prevents Lipopolysaccharide (LPS)-Induced Inflammatory Responses in BV2 Microglia Mediated by TREM2

Cellular Specificity of NF-κB Function in the Nervous System

(2019) Erica C. Dresselhaus et al.   Frontiers in Immunology

The endotoxin hypothesis of neurodegeneration

(2019) Guy C. Brown   Journal of Neuroinflammation

TREM2 — a key player in microglial biology and Alzheimer disease

(2018) Tyler K. Ulland et al.   Nature Reviews Neurology

Microglial TREM2/DAP12 Signaling: A Double-Edged Sword in Neural Diseases

(2018) Hiroyuki Konishi et al.   Frontiers in Cellular Neuroscience

NRF2 and NF-қB interplay in cerebrovascular and neurodegenerative disorders: Molecular mechanisms and possible therapeutic approaches

(2018) Farzane Sivandzade et al.   Redox Biology

Sirt3 protects dopaminergic neurons from mitochondrial oxidative stress

(2017) Han Shi et al.   HUMAN MOLECULAR GENETICS

Microglia in the TBI brain: The good, the bad, and the dysregulated

(2016) David J. Loane et al.   EXPERIMENTAL NEUROLOGY

DAP12 Stabilizes the C-terminal Fragment of the Triggering Receptor Expressed on Myeloid Cells-2 (TREM2) and Protects against LPS-induced Pro-inflammatory Response

(2015) Li Zhong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Central nervous system myeloid cells as drug targets: current status and translational challenges

(2015) Knut Biber et al.   NATURE REVIEWS DRUG DISCOVERY

Cellular and Molecular Mediators of Neuroinflammation in the Pathogenesis of Parkinson’s Disease

(2013) Sandeep Vasant More et al.   MEDIATORS OF INFLAMMATION

OA03.04. An assessment of the effectiveness of acupuncture for the Trauma Spectrum Response: results of a rapid evidence assessment of the literature (REAL)

(2012) C Lee et al.   BMC Complementary and Alternative Medicine

Impact of d-pinitol on the attenuation of proinflammatory cytokines, hyperglycemia-mediated oxidative stress and protection of kidney tissue ultrastructure in streptozotocin-induced diabetic rats

(2010) Selvaraj Sivakumar et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Inflammation in neurodegenerative diseases

(2010) Sandra Amor et al.   IMMUNOLOGY

Pancreatic tissue protective nature of D-Pinitol studied in streptozotocin-mediated oxidative stress in experimental diabetic rats

(2009) Selvaraj Sivakumar et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Molecular Targets of Nutraceuticals Derived from Dietary Spices: Potential Role in Suppression of Inflammation and Tumorigenesis

(2009) Bharat B. Aggarwal et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Relationship between microglial activation and dopaminergic neuronal loss in the substantia nigra: a time course study in a 6-hydroxydopamine model of Parkinson’s disease

(2009) Lilia Marinova-Mutafchieva et al.   JOURNAL OF NEUROCHEMISTRY

NF- B in the Nervous System

(2009) B. Kaltschmidt et al.   Cold Spring Harbor Perspectives in Biology

Pinitol targets nuclear factor-κB activation pathway leading to inhibition of gene products associated with proliferation, apoptosis, invasion, and angiogenesis

(2008) Gautam Sethi et al.   MOLECULAR CANCER THERAPEUTICS

Systemic infection and inflammation in acute CNS injury and chronic neurodegeneration: Underlying mechanisms

(2008) J.L. Teeling et al.   NEUROSCIENCE