A disease associated mutant reveals how Ltv1 orchestrates RP assembly and rRNA folding of the small ribosomal subunit head

Evolutionarily conserved inhibitory uORFs sensitize Hox mRNA translation to start codon selection stringency

(2022) Ivaylo P. Ivanov et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Using DMS-MaPseq to uncover the roles of DEAD-box proteins in ribosome assembly

(2022) Xin Liu et al.   METHODS

The nucleoplasmic phase of pre-40S formation prior to nuclear export

(2022) Jingdong Cheng et al.   NUCLEIC ACIDS RESEARCH

Assembly factors chaperone ribosomal RNA folding by isolating helical junctions that are prone to misfolding

(2021) Haina Huang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nucleolar maturation of the human small subunit processome

(2021) Sameer Singh et al.   SCIENCE

A roadmap for rRNA folding and assembly during transcription

(2021) Margaret L. Rodgers et al.   TRENDS IN BIOCHEMICAL SCIENCES

Mutations in the ribosome biogenesis factor gene LTV1 are linked to LIPHAK syndrome, a novel poikiloderma-like disorder

(2021) Ji Hoon Han et al.   HUMAN MOLECULAR GENETICS

Role of the 40S beak ribosomal protein eS12 in ribosome biogenesis and function in Saccharomyces cerevisiae

(2020) Sara Martín-Villanueva et al.   RNA Biology

Quality control of 40S ribosome head assembly ensures scanning competence

(2020) Haina Huang et al.   JOURNAL OF CELL BIOLOGY

90S pre-ribosome transformation into the primordial 40S subunit

(2020) Jingdong Cheng et al.   SCIENCE

Cryo-EM structure of 90S small ribosomal subunit precursors in transition states

(2020) Yifei Du et al.   SCIENCE

An open interface in the pre-80S ribosome coordinated by ribosome assembly factors Tsr1 and Dim1 enables temporal regulation of Fap7

(2020) Jay Rai et al.   RNA

Conformational proofreading of distant 40S ribosomal subunit maturation events by a long-range communication mechanism

(2019) Valentin Mitterer et al.   Nature Communications

Structure of a eukaryotic cytoplasmic pre‐40S ribosomal subunit

(2018) Alain Scaiola et al.   EMBO JOURNAL

Ribosome biogenesis factor Ltv1 chaperones the assembly of the small subunit head

(2018) Jason C. Collins et al.   JOURNAL OF CELL BIOLOGY

Transcriptome-wide measurement of translation by ribosome profiling

(2017) Nicholas J. McGlincy et al.   METHODS

The ATPase Fap7 Tests the Ability to Carry Out Translocation-like Conformational Changes and Releases Dim1 during 40S Ribosome Maturation

(2017) Homa Ghalei et al.   MOLECULAR CELL

Ribosome Collision Is Critical for Quality Control during No-Go Decay

(2017) Carrie L. Simms et al.   MOLECULAR CELL

Ribosomopathy-like properties of murine and human cancers

(2017) Sucheta Kulkarni et al.   PLoS One

Ribosomopathies: There’s strength in numbers

(2017) Eric W. Mills et al.   SCIENCE

Structural Heterogeneity in Pre-40S Ribosomes

(2017) Matthew C. Johnson et al.   STRUCTURE

Cryo-EM structure of a late pre-40S ribosomal subunit from Saccharomyces cerevisiae

(2017) André Heuer et al.   eLife

Architecture of the 90S Pre-ribosome: A Structural View on the Birth of the Eukaryotic Ribosome

(2016) Markus Kornprobst et al.   CELL

The eukaryote-specific N-terminal extension of ribosomal protein S31 contributes to the assembly and function of 40S ribosomal subunits

(2016) Antonio Fernández-Pevida et al.   NUCLEIC ACIDS RESEARCH

Sequential domain assembly of ribosomal protein S3 drives 40S subunit maturation

(2016) Valentin Mitterer et al.   Nature Communications

Nuclear import of dimerized ribosomal protein Rps3 in complex with its chaperone Yar1

(2016) Valentin Mitterer et al.   Scientific Reports

Hrr25/CK1δ-directed release of Ltv1 from pre-40S ribosomes is necessary for ribosome assembly and cell growth

(2015) Homa Ghalei et al.   JOURNAL OF CELL BIOLOGY

Skewer: a fast and accurate adapter trimmer for next-generation sequencing paired-end reads

(2014) Hongshan Jiang et al.   BMC BIOINFORMATICS

Snapshots of pre-rRNA structural flexibility reveal eukaryotic 40S assembly dynamics at nucleotide resolution

(2014) Ralph D. Hector et al.   NUCLEIC ACIDS RESEARCH

A Translation-Like Cycle Is a Quality Control Checkpoint for Maturing 40S Ribosome Subunits

(2012) Bethany S. Strunk et al.   CELL

Proofreading of pre-40S ribosome maturation by a translation initiation factor and 60S subunits

(2012) Simon Lebaron et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Protein-Protein Interactions within Late Pre-40S Ribosomes

(2011) Melody G. Campbell et al.   PLoS One

Ribosome Assembly Factors Prevent Premature Translation Initiation by 40S Assembly Intermediates

(2011) B. S. Strunk et al.   SCIENCE

Linear ubiquitin fusion to Rps31 and its subsequent cleavage are required for the efficient production and functional integrity of 40S ribosomal subunits

(2009) Thierry Lacombe et al.   MOLECULAR MICROBIOLOGY