Assembly factors chaperone ribosomal RNA folding by isolating helical junctions that are prone to misfolding

Loss of m1acp3Ψ Ribosomal RNA Modification Is a Major Feature of Cancer

(2020) Artem Babaian et al.   Cell Reports

Quality control of 40S ribosome head assembly ensures scanning competence

(2020) Haina Huang et al.   JOURNAL OF CELL BIOLOGY

Alternative Conformations and Motions Adopted by 30S Ribosomal Subunits Visualized by Cryo-Electron Microscopy.

(2020) Dushyant Jahagirdar et al.   RNA

90S pre-ribosome transformation into the primordial 40S subunit

(2020) Jingdong Cheng et al.   SCIENCE

Cryo-EM structure of 90S small ribosomal subunit precursors in transition states

(2020) Yifei Du et al.   SCIENCE

An open interface in the pre-80S ribosome coordinated by ribosome assembly factors Tsr1 and Dim1 enables temporal regulation of Fap7

(2020) Jay Rai et al.   RNA

Uncovering the assembly pathway of human ribosomes and its emerging links to disease

(2019) Katherine E Bohnsack et al.   EMBO JOURNAL

The roles of structural dynamics in the cellular functions of RNAs

(2019) Laura R. Ganser et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Conformational switches control early maturation of the eukaryotic small ribosomal subunit

(2019) Mirjam Hunziker et al.   eLife

Transcription Increases the Cooperativity of Ribonucleoprotein Assembly

(2019) Margaret L. Rodgers et al.   CELL

Transient Protein-RNA Interactions Guide Nascent Ribosomal RNA Folding

(2019) Olivier Duss et al.   CELL

Structure of a eukaryotic cytoplasmic pre‐40S ribosomal subunit

(2018) Alain Scaiola et al.   EMBO JOURNAL

Translation Elongation and Recoding in Eukaryotes

(2018) Thomas E. Dever et al.   Cold Spring Harbor Perspectives in Biology

Hidden Structural Modules in a Cooperative RNA Folding Transition

(2018) Brant Gracia et al.   Cell Reports

Eurokaryotic Ribosome Assembly

(2018) Jochen Baßler et al.   Annual Review of Biochemistry

Ribosome biogenesis factor Ltv1 chaperones the assembly of the small subunit head

(2018) Jason C. Collins et al.   JOURNAL OF CELL BIOLOGY

The Story of RNA Folding, as Told in Epochs

(2018) Daniel Herschlag et al.   Cold Spring Harbor Perspectives in Biology

Transcriptome-wide measurement of translation by ribosome profiling

(2017) Nicholas J. McGlincy et al.   METHODS

The ATPase Fap7 Tests the Ability to Carry Out Translocation-like Conformational Changes and Releases Dim1 during 40S Ribosome Maturation

(2017) Homa Ghalei et al.   MOLECULAR CELL

3.2-Å-resolution structure of the 90S preribosome before A1 pre-rRNA cleavage

(2017) Jingdong Cheng et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The complete structure of the small-subunit processome

(2017) Jonas Barandun et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Accurate detection of chemical modifications in RNA by mutational profiling (MaP) with ShapeMapper 2

(2017) Steven Busan et al.   RNA

Structural Heterogeneity in Pre-40S Ribosomes

(2017) Matthew C. Johnson et al.   STRUCTURE

Structural Insights into the Mechanism of Scanning and Start Codon Recognition in Eukaryotic Translation Initiation

(2017) Alan G. Hinnebusch   TRENDS IN BIOCHEMICAL SCIENCES

3.2-Å-resolution structure of the 90S preribosome before A1 pre-rRNA cleavage

(2017) Jingdong Cheng et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The complete structure of the small-subunit processome

(2017) Jonas Barandun et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Molecular architecture of the 90S small subunit pre-ribosome

(2017) Qi Sun et al.   eLife

Cryo-EM structure of a late pre-40S ribosomal subunit from Saccharomyces cerevisiae

(2017) André Heuer et al.   eLife

Mapping of Complete Set of Ribose and Base Modifications of Yeast rRNA by RP-HPLC and Mung Bean Nuclease Assay

(2017) Jun Yang et al.   PLoS One

DMS-MaPseq for genome-wide or targeted RNA structure probing in vivo

(2016) Meghan Zubradt et al.   NATURE METHODS

Ribosome biogenesis factor Tsr3 is the aminocarboxypropyl transferase responsible for 18S rRNA hypermodification in yeast and humans

(2016) Britta Meyer et al.   NUCLEIC ACIDS RESEARCH

Architecture of the yeast small subunit processome

(2016) Malik Chaker-Margot et al.   SCIENCE

Visualizing the formation of an RNA folding intermediate through a fast highly modular secondary structure switch

(2016) Yi Xue et al.   Nature Communications

Hrr25/CK1δ-directed release of Ltv1 from pre-40S ribosomes is necessary for ribosome assembly and cell growth

(2015) Homa Ghalei et al.   JOURNAL OF CELL BIOLOGY

Formation of Tertiary Interactions during rRNA GTPase Center Folding

(2015) Michael J. Rau et al.   JOURNAL OF MOLECULAR BIOLOGY

Skewer: a fast and accurate adapter trimmer for next-generation sequencing paired-end reads

(2014) Hongshan Jiang et al.   BMC BIOINFORMATICS

Snapshots of pre-rRNA structural flexibility reveal eukaryotic 40S assembly dynamics at nucleotide resolution

(2014) Ralph D. Hector et al.   NUCLEIC ACIDS RESEARCH

Ribosome Biogenesis in the Yeast Saccharomyces cerevisiae

(2013) John L. Woolford et al.   GENETICS

A Translation-Like Cycle Is a Quality Control Checkpoint for Maturing 40S Ribosome Subunits

(2012) Bethany S. Strunk et al.   CELL

ATPase-dependent role of the atypical kinase Rio2 on the evolving pre-40S ribosomal subunit

(2012) Sébastien Ferreira-Cerca et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The structural stabilization of the κ three-way junction by Mg(II) represents the first step in the folding of a group II intron

(2012) Daniela Donghi et al.   NUCLEIC ACIDS RESEARCH

ATP-Dependent Roles of the DEAD-Box Protein Mss116p in Group II Intron Splicing In Vitro and In Vivo

(2011) Jeffrey P. Potratz et al.   JOURNAL OF MOLECULAR BIOLOGY

Ribosome Assembly Factors Prevent Premature Translation Initiation by 40S Assembly Intermediates

(2011) B. S. Strunk et al.   SCIENCE

The Structure of the Eukaryotic Ribosome at 3.0 A Resolution

(2011) A. Ben-Shem et al.   SCIENCE

An RNA Conformational Switch Regulates Pre-18S rRNA Cleavage

(2010) Allison C. Lamanna et al.   JOURNAL OF MOLECULAR BIOLOGY

The DEAH Box ATPases Prp16 and Prp43 Cooperate to Proofread 5′ Splice Site Cleavage during Pre-mRNA Splicing

(2010) Prakash Koodathingal et al.   MOLECULAR CELL

The Bowen–Conradi syndrome protein Nep1 (Emg1) has a dual role in eukaryotic ribosome biogenesis, as an essential assembly factor and in the methylation of Ψ1191 in yeast 18S rRNA

(2010) Britta Meyer et al.   NUCLEIC ACIDS RESEARCH

S16 throws a conformational switch during assembly of 30S 5′ domain

(2009) Priya Ramaswamy et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Loss of rRNA modifications in the decoding center of the ribosome impairs translation and strongly delays pre-rRNA processing

(2009) X.-h. Liang et al.   RNA

Navigating the ribosome's metastable energy landscape

(2009) James B. Munro et al.   TRENDS IN BIOCHEMICAL SCIENCES

Concurrent nucleation of 16S folding and induced fit in 30S ribosome assembly

(2008) Tadepalli Adilakshmi et al.   NATURE