The nucleoplasmic phase of pre-40S formation prior to nuclear export

The final step of 40S ribosomal subunit maturation is controlled by a dual key lock

(2021) Laura Plassart et al.   eLife

Structural basis of successive adenosine modifications by the conserved ribosomal methyltransferase KsgA

(2021) Niklas C Stephan et al.   NUCLEIC ACIDS RESEARCH

Nucleolar maturation of the human small subunit processome

(2021) Sameer Singh et al.   SCIENCE

A conserved rRNA switch is central to decoding site maturation on the small ribosomal subunit

(2021) Andreas Schedlbauer et al.   Science Advances

Structural basis for translational shutdown and immune evasion by the Nsp1 protein of SARS-CoV-2

(2020) Matthias Thoms et al.   SCIENCE

90S pre-ribosome transformation into the primordial 40S subunit

(2020) Jingdong Cheng et al.   SCIENCE

Cryo-EM structure of 90S small ribosomal subunit precursors in transition states

(2020) Yifei Du et al.   SCIENCE

A structural inventory of native ribosomal ABCE1‐43S pre‐initiation complexes

(2020) Hanna Kratzat et al.   EMBO JOURNAL

Structure of the Maturing 90S Pre-ribosome in Association with the RNA Exosome

(2020) Benjamin Lau et al.   MOLECULAR CELL

Structural basis for the final steps of human 40S ribosome maturation

(2020) Michael Ameismeier et al.   NATURE

An open interface in the pre-80S ribosome coordinated by ribosome assembly factors Tsr1 and Dim1 enables temporal regulation of Fap7

(2020) Jay Rai et al.   RNA

Bud23 promotes the final disassembly of the small subunit Processome in Saccharomyces cerevisiae

(2020) Joshua J. Black et al.   PLoS Genetics

Molecular mechanism of the RNA helicase DHX37 and its activation by UTP14 in ribosome biogenesis

(2019) Franziska Boneberg et al.   RNA

Crystal structures of Rea1-MIDAS bound to its ribosome assembly factor ligands resembling integrin–ligand-type complexes

(2019) Yasar Luqman Ahmed et al.   Nature Communications

Thermophile 90S Pre-ribosome Structures Reveal the Reverse Order of Co-transcriptional 18S rRNA Subdomain Integration

(2019) Jingdong Cheng et al.   MOLECULAR CELL

A kinase-dependent checkpoint prevents escape of immature ribosomes into the translating pool

(2019) Melissa D. Parker et al.   PLOS BIOLOGY

Structure of a eukaryotic cytoplasmic pre‐40S ribosomal subunit

(2018) Alain Scaiola et al.   EMBO JOURNAL

Modular assembly of the nucleolar pre-60S ribosomal subunit

(2018) Zahra Assur Sanghai et al.   NATURE

Utp14 interaction with the Small Subunit Processome

(2018) Joshua J Black et al.   RNA

Cryo-EM structure of an early precursor of large ribosomal subunit reveals a half-assembled intermediate

(2018) Dejian Zhou et al.   Protein & Cell

Small Molecules Co-targeting CKIα and the Transcriptional Kinases CDK7/9 Control AML in Preclinical Models

(2018) Waleed Minzel et al.   CELL

Visualizing late states of human 40S ribosomal subunit maturation

(2018) Michael Ameismeier et al.   NATURE

Eurokaryotic Ribosome Assembly

(2018) Jochen Baßler et al.   Annual Review of Biochemistry

Ribosome assembly coming into focus

(2018) Sebastian Klinge et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

New tools for automated high-resolution cryo-EM structure determination in RELION-3

(2018) Jasenko Zivanov et al.   eLife

MotionCor2: anisotropic correction of beam-induced motion for improved cryo-electron microscopy

(2017) Shawn Q Zheng et al.   NATURE METHODS

Eukaryotic ribosome assembly, transport and quality control

(2017) Cohue Peña et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Interaction network of the ribosome assembly machinery from a eukaryotic thermophile

(2017) Jochen Baßler et al.   PROTEIN SCIENCE

UCSF ChimeraX: Meeting modern challenges in visualization and analysis

(2017) Thomas D. Goddard et al.   PROTEIN SCIENCE

Structural Heterogeneity in Pre-40S Ribosomes

(2017) Matthew C. Johnson et al.   STRUCTURE

Eukaryotic ribosome assembly, transport and quality control

(2017) Cohue Peña et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Molecular architecture of the 90S small subunit pre-ribosome

(2017) Qi Sun et al.   eLife

Cryo-EM structure of a late pre-40S ribosomal subunit from Saccharomyces cerevisiae

(2017) André Heuer et al.   eLife

Architecture of the 90S Pre-ribosome: A Structural View on the Birth of the Eukaryotic Ribosome

(2016) Markus Kornprobst et al.   CELL

Gctf: Real-time CTF determination and correction

(2016) Kai Zhang   JOURNAL OF STRUCTURAL BIOLOGY

Utp14 Recruits and Activates the RNA Helicase Dhr1 To Undock U3 snoRNA from the Preribosome

(2016) Jieyi Zhu et al.   MOLECULAR AND CELLULAR BIOLOGY

Architecture of the yeast small subunit processome

(2016) Malik Chaker-Margot et al.   SCIENCE

Pre-40S ribosome biogenesis factor Tsr1 is an inactive structural mimic of translational GTPases

(2016) Urszula M. McCaughan et al.   Nature Communications

Hrr25/CK1δ-directed release of Ltv1 from pre-40S ribosomes is necessary for ribosome assembly and cell growth

(2015) Homa Ghalei et al.   JOURNAL OF CELL BIOLOGY

CTFFIND4: Fast and accurate defocus estimation from electron micrographs

(2015) Alexis Rohou et al.   JOURNAL OF STRUCTURAL BIOLOGY

The human 18S rRNA base methyltransferases DIMT1L and WBSCR22-TRMT112 but not rRNA modification are required for ribosome biogenesis

(2015) Christiane Zorbas et al.   MOLECULAR BIOLOGY OF THE CELL

Architecture of the Rix1–Rea1 checkpoint machinery during pre-60S-ribosome remodeling

(2015) Clara Barrio-Garcia et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Architecture of the Rix1–Rea1 checkpoint machinery during pre-60S-ribosome remodeling

(2015) Clara Barrio-Garcia et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The DEAH-box Helicase Dhr1 Dissociates U3 from the Pre-rRNA to Promote Formation of the Central Pseudoknot

(2015) Richa Sardana et al.   PLOS BIOLOGY

A non-canonical mechanism for Crm1-export cargo complex assembly

(2015) Ute Fischer et al.   eLife

Genetic Analysis of the Ribosome Biogenesis Factor Ltv1 of Saccharomyces cerevisiae

(2014) J. R. Merwin et al.   GENETICS

SWISS-MODEL: modelling protein tertiary and quaternary structure using evolutionary information

(2014) Marco Biasini et al.   NUCLEIC ACIDS RESEARCH

Structural and functional studies of Bud23–Trm112 reveal 18S rRNAN7-G1575 methylation occurs on late 40S precursor ribosomes

(2014) Juliette Létoquart et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rrp12 and the Exportin Crm1 Participate in Late Assembly Events in the Nucleolus during 40S Ribosomal Subunit Biogenesis

(2014) Giulia Moriggi et al.   PLoS Genetics

Ribosome Biogenesis in the Yeast Saccharomyces cerevisiae

(2013) John L. Woolford et al.   GENETICS

Coupled GTPase and remodelling ATPase activities form a checkpoint for ribosome export

(2013) Yoshitaka Matsuo et al.   NATURE

Structural Insights into Methyltransferase KsgA Function in 30S Ribosomal Subunit Biogenesis

(2012) Daniel Boehringer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Role of Mex67-Mtr2 in the Nuclear Export of 40S Pre-Ribosomes

(2012) Marius B. Faza et al.   PLoS Genetics

Ribosome Assembly Factors Prevent Premature Translation Initiation by 40S Assembly Intermediates

(2011) B. S. Strunk et al.   SCIENCE

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Functional dichotomy of ribosomal proteins during the synthesis of mammalian 40S ribosomal subunits

(2010) Marie-Françoise O’Donohue et al.   JOURNAL OF CELL BIOLOGY

MolProbity: all-atom structure validation for macromolecular crystallography

(2009) Vincent B. Chen et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Distinct cytoplasmic maturation steps of 40S ribosomal subunit precursors require hRio2

(2009) Ivo Zemp et al.   JOURNAL OF CELL BIOLOGY

Bud23 Methylates G1575 of 18S rRNA and Is Required for Efficient Nuclear Export of Pre-40S Subunits

(2008) J. White et al.   MOLECULAR AND CELLULAR BIOLOGY