90S pre-ribosome transformation into the primordial 40S subunit

Molecular mechanism of the RNA helicase DHX37 and its activation by UTP14 in ribosome biogenesis

(2019) Franziska Boneberg et al.   RNA

The DEAH-box RNA helicase Dhr1 contains a remarkable carboxyl terminal domain essential for small ribosomal subunit biogenesis

(2019) Amlan Roychowdhury et al.   NUCLEIC ACIDS RESEARCH

Conformational proofreading of distant 40S ribosomal subunit maturation events by a long-range communication mechanism

(2019) Valentin Mitterer et al.   Nature Communications

Conformational switches control early maturation of the eukaryotic small ribosomal subunit

(2019) Mirjam Hunziker et al.   eLife

At least two molecules of the RNA helicase Has1 are simultaneously present in pre-ribosomes during ribosome biogenesis

(2019) Sivakumar Vadivel Gnanasundram et al.   NUCLEIC ACIDS RESEARCH

Structure of a eukaryotic cytoplasmic pre‐40S ribosomal subunit

(2018) Alain Scaiola et al.   EMBO JOURNAL

Turnover of aberrant pre-40S pre-ribosomal particles is initiated by a novel endonucleolytic decay pathway

(2018) Elodie Choque et al.   NUCLEIC ACIDS RESEARCH

Structural and functional analysis of Utp24, an endonuclease for processing 18S ribosomal RNA

(2018) Weidong An et al.   PLoS One

Utp14 interaction with the Small Subunit Processome

(2018) Joshua J Black et al.   RNA

Visualizing late states of human 40S ribosomal subunit maturation

(2018) Michael Ameismeier et al.   NATURE

Eurokaryotic Ribosome Assembly

(2018) Jochen Baßler et al.   Annual Review of Biochemistry

Ribosome assembly coming into focus

(2018) Sebastian Klinge et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

New tools for automated high-resolution cryo-EM structure determination in RELION-3

(2018) Jasenko Zivanov et al.   eLife

MotionCor2: anisotropic correction of beam-induced motion for improved cryo-electron microscopy

(2017) Shawn Q Zheng et al.   NATURE METHODS

3.2-Å-resolution structure of the 90S preribosome before A1 pre-rRNA cleavage

(2017) Jingdong Cheng et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The complete structure of the small-subunit processome

(2017) Jonas Barandun et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Aminoglycoside interactions and impacts on the eukaryotic ribosome

(2017) Irina Prokhorova et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural conservation of the PIN domain active site across all domains of life

(2017) M. Senissar et al.   PROTEIN SCIENCE

UCSF ChimeraX: Meeting modern challenges in visualization and analysis

(2017) Thomas D. Goddard et al.   PROTEIN SCIENCE

Structural Heterogeneity in Pre-40S Ribosomes

(2017) Matthew C. Johnson et al.   STRUCTURE

Interdependent action of KH domain proteins Krr1 and Dim2 drive the 40S platform assembly

(2017) Miriam Sturm et al.   Nature Communications

3.2-Å-resolution structure of the 90S preribosome before A1 pre-rRNA cleavage

(2017) Jingdong Cheng et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The complete structure of the small-subunit processome

(2017) Jonas Barandun et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Cryo-EM structure of a late pre-40S ribosomal subunit from Saccharomyces cerevisiae

(2017) André Heuer et al.   eLife

Architecture of the 90S Pre-ribosome: A Structural View on the Birth of the Eukaryotic Ribosome

(2016) Markus Kornprobst et al.   CELL

Stepwise and dynamic assembly of the earliest precursors of small ribosomal subunits in yeast

(2016) Liman Zhang et al.   GENES & DEVELOPMENT

Gctf: Real-time CTF determination and correction

(2016) Kai Zhang   JOURNAL OF STRUCTURAL BIOLOGY

Utp14 Recruits and Activates the RNA Helicase Dhr1 To Undock U3 snoRNA from the Preribosome

(2016) Jieyi Zhu et al.   MOLECULAR AND CELLULAR BIOLOGY

The PIN domain endonuclease Utp24 cleaves pre-ribosomal RNA at two coupled sites in yeast and humans

(2016) Graeme R. Wells et al.   NUCLEIC ACIDS RESEARCH

Structure of a human pre-40S particle points to a role for RACK1 in the final steps of 18S rRNA processing

(2016) Natacha Larburu et al.   NUCLEIC ACIDS RESEARCH

Architecture of the yeast small subunit processome

(2016) Malik Chaker-Margot et al.   SCIENCE

Structural and functional analysis of the RNA helicase Prp43 from the thermophilic eukaryoteChaetomium thermophilum

(2016) Marcel J. Tauchert et al.   Acta Crystallographica Section F-Structural Biology Communications

The Exosome Is Recruited to RNA Substrates through Specific Adaptor Proteins

(2015) Matthias Thoms et al.   CELL

CTFFIND4: Fast and accurate defocus estimation from electron micrographs

(2015) Alexis Rohou et al.   JOURNAL OF STRUCTURAL BIOLOGY

The human 18S rRNA base methyltransferases DIMT1L and WBSCR22-TRMT112 but not rRNA modification are required for ribosome biogenesis

(2015) Christiane Zorbas et al.   MOLECULAR BIOLOGY OF THE CELL

Stage-specific assembly events of the 6-MDa small-subunit processome initiate eukaryotic ribosome biogenesis

(2015) Malik Chaker-Margot et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

hUTP24 is essential for processing of the human rRNA precursor at site A1, but not at site A0

(2015) Rafal Tomecki et al.   RNA Biology

Stage-specific assembly events of the 6-MDa small-subunit processome initiate eukaryotic ribosome biogenesis

(2015) Malik Chaker-Margot et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The DEAH-box Helicase Dhr1 Dissociates U3 from the Pre-rRNA to Promote Formation of the Central Pseudoknot

(2015) Richa Sardana et al.   PLOS BIOLOGY

Physical and Functional Interaction between the Methyltransferase Bud23 and the Essential DEAH-Box RNA Helicase Ecm16

(2014) R. Sardana et al.   MOLECULAR AND CELLULAR BIOLOGY

SWISS-MODEL: modelling protein tertiary and quaternary structure using evolutionary information

(2014) Marco Biasini et al.   NUCLEIC ACIDS RESEARCH

Ribosome Biogenesis in the Yeast Saccharomyces cerevisiae

(2013) John L. Woolford et al.   GENETICS

Automated 3D structure composition for large RNAs

(2012) Mariusz Popenda et al.   NUCLEIC ACIDS RESEARCH

Elucidation of the assembly events required for the recruitment of Utp20, Imp4 and Bms1 onto nascent pre-ribosomes

(2011) Jorge Pérez-Fernández et al.   NUCLEIC ACIDS RESEARCH

Ribosome Assembly Factors Prevent Premature Translation Initiation by 40S Assembly Intermediates

(2011) B. S. Strunk et al.   SCIENCE

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Ribosomopathies: human disorders of ribosome dysfunction

(2010) A. Narla et al.   BLOOD

Tandem affinity purification combined with inducible shRNA expression as a tool to study the maturation of macromolecular assemblies

(2010) E. Wyler et al.   RNA

MolProbity: all-atom structure validation for macromolecular crystallography

(2009) Vincent B. Chen et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification

(2008) Jürgen Cox et al.   NATURE BIOTECHNOLOGY