Exogenous melatonin ameliorates steroid-induced osteonecrosis of the femoral head by modulating ferroptosis through GDF15-mediated signaling

Melatonin protects against cadmium-induced oxidative stress via mitochondrial STAT3 signaling in human prostate stromal cells

(2023) Moonjung Hyun et al.   Communications Biology

Activation of the transcription factor NRF2 mediates the anti-inflammatory properties of a subset of over-the-counter and prescription NSAIDs

(2022) Anna Eisenstein et al.   IMMUNITY

Decreased Ankyrin Expression Is Associated with Repressed eNOS Signaling, Cell Proliferation, and Osteogenic Differentiation in Osteonecrosis of the Femoral Head

(2022) Rio L.C. Lin et al.   JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME

C/EBPα regulates the fate of bone marrow mesenchymal stem cells and steroid-induced avascular necrosis of the femoral head by targeting the PPARγ signalling pathway

(2022) Ping Duan et al.   Stem Cell Research & Therapy

Melatonin: Potential avenue for treating iron overload disorders

(2022) Jiancheng Yang et al.   AGEING RESEARCH REVIEWS

mTORC1 beyond anabolic metabolism: Regulation of cell death

(2022) Jiajun Zhu et al.   JOURNAL OF CELL BIOLOGY

SIRT6 Prevents Glucocorticoid-Induced Osteonecrosis of the Femoral Head in Rats

(2022) Lun Fang et al.   Oxidative Medicine and Cellular Longevity

Melatonin in Endometriosis: Mechanistic Understanding and Clinical Insight

(2022) Yiran Li et al.   Nutrients

Is Melatonin the “Next Vitamin D”?: A Review of Emerging Science, Clinical Uses, Safety, and Dietary Supplements

(2022) Deanna M. Minich et al.   Nutrients

The role of melatonin in the development of postmenopausal osteoporosis

(2022) Keda Yang et al.   Frontiers in Pharmacology

System Xc−/GSH/GPX4 axis: An important antioxidant system for the ferroptosis in drug-resistant solid tumor therapy

(2022) Feng-Jiao Li et al.   Frontiers in Pharmacology

Partial prevention of glucocorticoid-induced osteocyte deterioration in young male mice with osteocrin gene therapy

(2022) Courtney M. Mazur et al.   iScience

Oxidative Stress Management in Cardiorenal Diseases: Focus on Novel Antidiabetic Agents, Finerenone, and Melatonin

(2022) Panagiotis Theofilis et al.   Life-Basel

Adverse effects of oxidative stress on bone and vasculature in corticosteroid-associated osteonecrosis: potential role of Nrf2 in cytoprotection

(2021) Yusuke Kubo et al.   ANTIOXIDANTS & REDOX SIGNALING

Broadening horizons: the role of ferroptosis in cancer

(2021) Xin Chen et al.   Nature Reviews Clinical Oncology

GDF15: emerging biology and therapeutic applications for obesity and cardiometabolic disease

(2021) Dongdong Wang et al.   Nature Reviews Endocrinology

Artemisinin Reverses Glucocorticoid-Induced Injury in Bone Marrow-Derived Mesenchymal Stem Cells through Regulation of ERK1/2-CREB Signaling Pathway

(2021) Jiankang Fang et al.   Oxidative Medicine and Cellular Longevity

Pathophysiological role of growth differentiation factor 15 (GDF15) in obesity, cancer, and cachexia

(2021) Jawed Akhtar Siddiqui et al.   CYTOKINE & GROWTH FACTOR REVIEWS

PARK7 promotes repair in early steroid-induced osteonecrosis of the femoral head by enhancing resistance to stress-induced apoptosis in bone marrow mesenchymal stem cells via regulation of the Nrf2 signaling pathway

(2021) Fei Zhang et al.   Cell Death & Disease

Melatonin up‐regulates bone marrow mesenchymal stem cells osteogenic action but suppresses their mediated osteoclastogenesis via MT 2 ‐inactivated NF‐κB pathway

(2020) Yi Zhou et al.   BRITISH JOURNAL OF PHARMACOLOGY

Guidelines for clinical diagnosis and treatment of osteonecrosis of the femoral head in adults (2019 version)

(2020) Dewei Zhao et al.   Journal of Orthopaedic Translation

Sustained Release of Melatonin from GelMA Liposomes Reduced Osteoblast Apoptosis and Improved Implant Osseointegration in Osteoporosis

(2020) Long Xiao et al.   Oxidative Medicine and Cellular Longevity

Mechanisms of bone development and repair

(2020) Ankit Salhotra et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Oxidative Damage and Antioxidant Defense in Ferroptosis

(2020) Feimei Kuang et al.   Frontiers in Cell and Developmental Biology

Epidemiological Study Based on China Osteonecrosis of the Femoral Head Database

(2020) Biao Tan et al.   Orthopaedic Surgery

Melatonin: Another avenue for treating osteoporosis?

(2019) Tian Li et al.   JOURNAL OF PINEAL RESEARCH

Melatonin Increases Bone Mass around the Prostheses of OVX Rats by Ameliorating Mitochondrial Oxidative Stress via the SIRT3/SOD2 Signaling Pathway

(2019) Wei Zhou et al.   Oxidative Medicine and Cellular Longevity

New strategy of bone marrow mesenchymal stem cells against oxidative stress injury via Nrf2 pathway: oxidative stress preconditioning

(2019) Fei Zhang et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Melatonin receptor structures shed new light on melatonin research

(2019) Erika Cecon et al.   JOURNAL OF PINEAL RESEARCH

Biological effects of melatonin on osteoblast/osteoclast cocultures, bone, and quality of life: Implications of a role for MT2 melatonin receptors, MEK1/2, and MEK5 in melatonin-mediated osteoblastogenesis

(2018) Sifat Maria et al.   JOURNAL OF PINEAL RESEARCH

MELATONIN AS A HORMONE: NEW PHYSIOLOGICAL AND CLINICAL INSIGHTS

(2018) José Cipolla-Neto et al.   ENDOCRINE REVIEWS

Molecular mechanisms of glucocorticoid resistance in systemic lupus erythematosus: A review

(2018) Hongyan Gao et al.   LIFE SCIENCES

Effects of melatonin on oocyte developmental competence and the role of melatonin receptor 1 in juvenile goats

(2018) Sandra Soto-Heras et al.   REPRODUCTION IN DOMESTIC ANIMALS

Melatonin potentiates the antitumor effect of curcumin by inhibiting IKKβ/NF-κB/COX-2 signaling pathway

(2017) Sandeep Shrestha et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

The physiopathology of avascular necrosis of the femoral head: an update

(2016) Enrique Guerado et al.   INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED

Melatonin as an antioxidant: under promises but over delivers

(2016) Russel J. Reiter et al.   JOURNAL OF PINEAL RESEARCH

Ferroptosis: Death by Lipid Peroxidation

(2016) Wan Seok Yang et al.   TRENDS IN CELL BIOLOGY

Skeletal (stromal) stem cells: An update on intracellular signaling pathways controlling osteoblast differentiation

(2015) Basem M. Abdallah et al.   BONE

Melatonin prevents lung injury induced by hepatic ischemia–reperfusion through anti-inflammatory and anti-apoptosis effects

(2015) Li Zhou et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Beneficial effect of grape seed proanthocyanidin extract in rabbits with steroid-induced osteonecrosis via protecting against oxidative stress and apoptosis

(2015) Qichun Song et al.   JOURNAL OF ORTHOPAEDIC SCIENCE

Hydrogen-rich saline attenuates steroid-associated femoral head necrosis through inhibition of oxidative stress in a rabbit model

(2015) SHENG-LI HUANG et al.   Experimental and Therapeutic Medicine

Preventive effects of coenzyme Q10 (CoQ10) on steroid-induced osteonecrosis in rats

(2014) Erkam KOMURCU   Acta Orthopaedica et Traumatologica Turcica

Influence of glucocorticoids on the osteogenic differentiation of rat bone marrow-derived mesenchymal stem cells

(2014) Da-An Zhou et al.   BMC MUSCULOSKELETAL DISORDERS

A Review of Osteocyte Function and the Emerging Importance of Sclerostin

(2014) Jocelyn T Compton et al.   JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME

N-cadherin in osteolineage cells is not required for maintenance of hematopoietic stem cells

(2012) A. M. Greenbaum et al.   BLOOD

Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death

(2012) Scott J. Dixon et al.   CELL

Edaravone, a novel free radical scavenger, prevents steroid-induced osteonecrosis in rabbits

(2012) G.-Y. Li et al.   RHEUMATOLOGY

Osteonecrosis development in a novel rat model characterized by a single application of oxidative stress

(2011) Toru Ichiseki et al.   ARTHRITIS AND RHEUMATISM

Glucocorticoids in osteonecrosis of the femoral head: A new understanding of the mechanisms of action

(2009) Mohammad Amin Kerachian et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY