SIRT6 Prevents Glucocorticoid-Induced Osteonecrosis of the Femoral Head in Rats

SIRT6 promotes angiogenesis and hemorrhage of carotid plaque via regulating HIF-1α and reactive oxygen species

(2021) Zhou Yang et al.   Cell Death & Disease

The EMT transcription factor ZEB1 blocks osteoblastic differentiation in bone development and osteosarcoma

(2021) Manuel Ruh et al.   JOURNAL OF PATHOLOGY

Sirtuin 6 (SIRT6) regulates redox homeostasis and signaling events in human articular chondrocytes

(2021) John A. Collins et al.   FREE RADICAL BIOLOGY AND MEDICINE

Therapeutic effect of SIRT3 on glucocorticoid-induced osteonecrosis of femoral head via intracellular oxidative suppression

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Hydrogen sulfide alleviates the anxiety-like and depressive-like behaviors of type 1 diabetic mice via inhibiting inflammation and ferroptosis

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Nontraumatic Osteonecrosis of the Femoral Head

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Immunohistochemical Studies of Age-Related Changes in Cell Proliferation and Angiogenesis during the Healing of Acetic Acid-Induced Gastric Ulcers in Rats

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The Proosteogenic and Proangiogenic Effects of Small Extracellular Vesicles Derived from Bone Marrow Mesenchymal Stem Cells Are Attenuated in Steroid-Induced Osteonecrosis of the Femoral Head

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Cystine‐glutamate antiporter xCT as a therapeutic target for cancer

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Osteogenic differentiation of rat bone mesenchymal stem cells modulated by MiR-186 via SIRT6

(2020) Jijie Xiao et al.   LIFE SCIENCES

Sirtuin 6: A potential therapeutic target for cardiovascular diseases

(2020) Xie Saiyang et al.   PHARMACOLOGICAL RESEARCH

Osteoblasts/Osteocytes sirtuin6 Is Vital to Preventing Ischemic Osteonecrosis Through Targeting VDR‐RANKL Signaling

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Melatonin Suppresses Ferroptosis Induced by High Glucose via Activation of the Nrf2/HO-1 Signaling Pathway in Type 2 Diabetic Osteoporosis

(2020) Hongdong Ma et al.   Oxidative Medicine and Cellular Longevity

Endothelial SIRT6 Is Vital to Prevent Hypertension and Associated Cardiorenal Injury Through Targeting Nkx3.2-GATA5 Signaling

(2019) Jian Guo et al.   CIRCULATION RESEARCH

Sirtuin 6 in preosteoclasts suppresses age- and estrogen deficiency-related bone loss by stabilizing estrogen receptor α

(2019) Young Jae Moon et al.   CELL DEATH AND DIFFERENTIATION

Osteonecrosis of the Femoral Head

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SIRT6 protects vascular endothelial cells from angiotensin II-induced apoptosis and oxidative stress by promoting the activation of Nrf2/ARE signaling

(2019) Yujuan Yang et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Extracellular vesicles from endothelial progenitor cells prevent steroid-induced osteoporosis by suppressing the ferroptotic pathway in mouse osteoblasts based on bioinformatics evidence

(2019) Jinsen Lu et al.   Scientific Reports

Exosomes derived from human CD34+ stem cells transfected with miR-26a prevent glucocorticoid-induced osteonecrosis of the femoral head by promoting angiogenesis and osteogenesis

(2019) Rongtai Zuo et al.   Stem Cell Research & Therapy

Inhibitory Effect of Sirtuin6 (SIRT6) on Osteogenic Differentiation of Bone Marrow Mesenchymal Stem Cells

(2019) Fei Xiao et al.   MEDICAL SCIENCE MONITOR

The pathogenesis of steroid-induced osteonecrosis of the femoral head: A systematic review of the literature

(2018) Ao Wang et al.   GENE

Animal models of steroid-induced osteonecrosis of the femoral head—a comprehensive research review up to 2018

(2018) Jianzhong Xu et al.   INTERNATIONAL ORTHOPAEDICS

Mechanisms of ferroptosis

(2016) Jennifer Yinuo Cao et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

COMP-Angiopoietin1 Potentiates the Effects of Bone Morphogenic Protein-2 on Ischemic Necrosis of the Femoral Head in Rats

(2014) Lu Zhou et al.   PLoS One

Mammalian Sirtuins: Biological Insights and Disease Relevance

(2010) Marcia C. Haigis et al.   Annual Review of Pathology-Mechanisms of Disease