Melatonin in Endometriosis: Mechanistic Understanding and Clinical Insight
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Title
Melatonin in Endometriosis: Mechanistic Understanding and Clinical Insight
Authors
Keywords
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Journal
Nutrients
Volume 14, Issue 19, Pages 4087
Publisher
MDPI AG
Online
2022-10-10
DOI
10.3390/nu14194087
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Note: Only part of the references are listed.- Melatonin promotes male reproductive performance and increases testosterone synthesis in mammalian Leydig cells
- (2021) Minghui Yang et al. BIOLOGY OF REPRODUCTION
- Anti-inflammatory effects of melatonin: A systematic review and meta-analysis of clinical trials
- (2021) Joshua H. Cho et al. BRAIN BEHAVIOR AND IMMUNITY
- Pharmaceuticals targeting signaling pathways of endometriosis as potential new medical treatment: A review
- (2021) Sze Wan Hung et al. MEDICINAL RESEARCH REVIEWS
- The crosstalk between melatonin and sex steroid hormones
- (2021) José Cipolla-Neto et al. NEUROENDOCRINOLOGY
- Melatonin and Phytomelatonin: Chemistry, Biosynthesis, Metabolism, Distribution and Bioactivity in Plants and Animals—An Overview
- (2021) Giuseppe Mannino et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Melatonin indirectly decreases gastric cancer cell proliferation and invasion via effects on cancer-associated fibroblasts
- (2021) Dongyang Liu et al. LIFE SCIENCES
- Melatonin suppresses ischemia-induced fibrosis by regulating miR-149
- (2020) Yong-Seok Han et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Melatonin Promotes Uterine and Placental Health: Potential Molecular Mechanisms
- (2020) Luiz Gustavo de Almeida Chuffa et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Estrogen Receptors and Endometriosis
- (2020) Elodie Chantalat et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Endometriosis
- (2020) Krina T. Zondervan et al. NEW ENGLAND JOURNAL OF MEDICINE
- Melatonin stimulates aromatase expression and estradiol production in human granulosa-lutein cells: relevance for high serum estradiol levels in patients with ovarian hyperstimulation syndrome
- (2020) Jung-Chien Cheng et al. EXPERIMENTAL AND MOLECULAR MEDICINE
- Endometriosis
- (2019) Serdar E Bulun et al. ENDOCRINE REVIEWS
- The role of inflammation, oxidative stress, angiogenesis, and apoptosis in the pathophysiology of endometriosis: Basic science and new insights based on gene expression
- (2019) Mansooreh Samimi et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Melatonin activity and receptor expression in endometrial tissue and endometriosis
- (2019) A A Mosher et al. HUMAN REPRODUCTION
- The endometrial immune environment of women with endometriosis
- (2019) Júlia Vallvé-Juanico et al. HUMAN REPRODUCTION UPDATE
- Modulation of apoptosis by melatonin for improving cancer treatment efficiency: An updated review
- (2019) Keywan Mortezaee et al. LIFE SCIENCES
- The usefulness of melatonin in the field of obstetrics and gynecology
- (2019) Rafael Genario et al. PHARMACOLOGICAL RESEARCH
- Therapeutic Opportunities in Colorectal Cancer: Focus on Melatonin Antioncogenic Action
- (2019) Hucong Wu et al. Biomed Research International
- Estrogen-Receptor Expression and Function in Female Reproductive Disease
- (2019) Zi-Run Tang et al. Cells
- Melatonin induces progesterone production in human granulosa-lutein cells through upregulation of StAR expression
- (2019) Lanlan Fang et al. Aging-US
- Impact of Melatonin Supplementation in Women with Unexplained Infertility Undergoing Fertility Treatment
- (2019) Javier Espino et al. Antioxidants
- SnapShot: Endometriosis
- (2019) Andrew W. Horne et al. CELL
- Melatonin suppresses epithelial‑to‑mesenchymal transition in the MG‑63 cell line
- (2019) Yongjun Chen et al. Molecular Medicine Reports
- New perspectives on the role of melatonin in human sleep, circadian rhythms and their regulation
- (2018) Nava Zisapel BRITISH JOURNAL OF PHARMACOLOGY
- Oral supplementation with melatonin reduces oxidative damage and concentrations of inducible nitric oxide synthase, VEGF and matrix metalloproteinase 9 in the retina of rats with streptozotocin/nicotinamide induced pre-diabetes
- (2018) Branka Djordjevic et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Current and emerging treatment options for endometriosis
- (2018) Simone Ferrero et al. EXPERT OPINION ON PHARMACOTHERAPY
- Melatonin inhibits epithelial‑to‑mesenchymal transition in gastric cancer cells via attenuation of IL‑1β/NF‑κB/MMP2/MMP9 signaling
- (2018) Xiaoting Wang et al. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
- Crosstalk between Notch, HIF-1α and GPER in Breast Cancer EMT
- (2018) Ernestina De Francesco et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- The neuroprotective role of melatonin in neurological disorders
- (2018) B. S. Alghamdi JOURNAL OF NEUROSCIENCE RESEARCH
- Melatonin improves endothelial function in vitro and prolongs pregnancy in women with early-onset preeclampsia
- (2018) Sebastian R Hobson et al. JOURNAL OF PINEAL RESEARCH
- Efficacy, safety and recurrence of new progestins and selective progesterone receptor modulator for the treatment of endometriosis: a comparison study in mice
- (2018) Bo Liang et al. Reproductive Biology and Endocrinology
- Melatonin inhibits 17β-estradiol-induced migration, invasion and epithelial-mesenchymal transition in normal and endometriotic endometrial epithelial cells
- (2018) Shasha Qi et al. Reproductive Biology and Endocrinology
- Endometriosis
- (2018) Krina T. Zondervan et al. Nature Reviews Disease Primers
- Melatonin in Assisted Reproductive Technology: A Pilot Double-Blind Randomized Placebo-Controlled Clinical Trial
- (2018) Shavi Fernando et al. Frontiers in Endocrinology
- Progesterone Receptor Status Predicts Response to Progestin Therapy in Endometriosis
- (2018) Valerie A Flores et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Melatonin in type 2 diabetes mellitus and obesity
- (2018) Angeliki Karamitri et al. Nature Reviews Endocrinology
- Complementary actions of melatonin on angiogenic factors, the angiopoietin/Tie2 axis and VEGF, in co‑cultures of human endothelial and breast cancer cells
- (2017) Alicia Gonz�lez-Gonz�lez et al. ONCOLOGY REPORTS
- Oxidative Stress and Endometriosis: A Systematic Review of the Literature
- (2017) Gennaro Scutiero et al. Oxidative Medicine and Cellular Longevity
- Melatonin Treatment May Be Able to Restore Menstrual Cyclicity in Women With PCOS: A Pilot Study
- (2017) Valeria Tagliaferri et al. Reproductive Sciences
- Inhibition of VEGF-Induced VEGFR-2 Activation and HUVEC Migration by Melatonin and Other Bioactive Indolic Compounds
- (2017) Ana Cerezo et al. Nutrients
- The potential therapeutic effect of melatonin on human ovarian cancer by inhibition of invasion and migration of cancer stem cells
- (2017) Maryam Akbarzadeh et al. Scientific Reports
- Melatonin Regulates Angiogenic Factors under Hypoxia in Breast Cancer Cell Lines
- (2016) Bruna Victorasso Jardim-Perassi et al. Anti-Cancer Agents in Medicinal Chemistry
- Decreased concentration of serum melatonin in nighttime compared with daytime female medical technologists in South Korea
- (2016) GiSeon Song et al. CHRONOBIOLOGY INTERNATIONAL
- Melatonin in Pregnancy: Effects on Brain Development and CNS Programming Disorders
- (2016) Lucas Sagrillo-Fagundes et al. CURRENT PHARMACEUTICAL DESIGN
- Oxidative stress in the pelvic cavity and its role in the pathogenesis of endometriosis
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- Melatonin and Human Cardiovascular Disease
- (2016) Seithikurippu R. Pandi-Perumal et al. JOURNAL OF CARDIOVASCULAR PHARMACOLOGY AND THERAPEUTICS
- Melatonin Represses Metastasis in Her2-Postive Human Breast Cancer Cells by Suppressing RSK2 Expression
- (2016) L. Mao et al. MOLECULAR CANCER RESEARCH
- Effect of Melatonin in Epithelial Mesenchymal Transition Markers and Invasive Properties of Breast Cancer Stem Cells of Canine and Human Cell Lines
- (2016) Naiane do Nascimento Gonçalves et al. PLoS One
- Efficacy of Anti-VEGF/VEGFR Agents on Animal Models of Endometriosis: A Systematic Review and Meta-Analysis
- (2016) Shuangge Liu et al. PLoS One
- The Safety of Melatonin in Humans
- (2015) Lars Peter Holst Andersen et al. CLINICAL DRUG INVESTIGATION
- Apoptosis is triggered by melatonin in anin vivomodel of ovarian carcinoma
- (2015) Luiz Gustavo A Chuffa et al. ENDOCRINE-RELATED CANCER
- Clinical pharmacokinetics of melatonin: a systematic review
- (2015) Nathja Groth Harpsøe et al. EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY
- Melatonin inhibits granulocyte adhesion to ICAM via MT3/QR2 and MT2 receptors
- (2015) Vitalij Černyšiov et al. INTERNATIONAL IMMUNOLOGY
- High membrane permeability for melatonin
- (2015) Haijie Yu et al. JOURNAL OF GENERAL PHYSIOLOGY
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- (2015) Sheng-Mao Wu et al. JOURNAL OF PINEAL RESEARCH
- Selective melatonin MT2 receptor ligands relieve neuropathic pain through modulation of brainstem descending antinociceptive pathways
- (2015) Martha Lopez-Canul et al. PAIN
- A role of melatonin in the treatment of low back pain
- (2015) Yu. M. Kurganova et al. Zhurnal Nevrologii I Psikhiatrii imeni S S Korsakova
- Melatonin inhibits AP-2β/hTERT, NF-κB/COX-2 and Akt/ERK and activates caspase/Cyto C signaling to enhance the antitumor activity of berberine in lung cancer cells
- (2015) Jian-Jun Lu et al. Oncotarget
- The effects of different doses of melatonin treatment on endometrial implants in an oophorectomized rat endometriosis model
- (2014) Nilufer Cetinkaya et al. ARCHIVES OF GYNECOLOGY AND OBSTETRICS
- Melatonin causes regression of endometriotic implants in rats by modulating angiogenesis, tissue levels of antioxidants and matrix metalloproteinases
- (2014) Bulent Yilmaz et al. ARCHIVES OF GYNECOLOGY AND OBSTETRICS
- Extrapineal melatonin: sources, regulation, and potential functions
- (2014) Darío Acuña-Castroviejo et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Regulation of EMT by Notch Signaling Pathway in Tumor Progression
- (2014) Yumei Li et al. CURRENT CANCER DRUG TARGETS
- Brain-derived neurotrophic factor as a driving force behind neuroplasticity in neuropathic and central sensitization pain: a new therapeutic target?
- (2014) Jo Nijs et al. EXPERT OPINION ON THERAPEUTIC TARGETS
- Oral melatonin supplementation improves oocyte and embryo quality in women undergoingin vitrofertilization-embryo transfer
- (2014) Takuji Nishihara et al. GYNECOLOGICAL ENDOCRINOLOGY
- ESHRE guideline: management of women with endometriosis
- (2014) G. A. J. Dunselman et al. HUMAN REPRODUCTION
- Peripheral changes in endometriosis-associated pain
- (2014) Matteo Morotti et al. HUMAN REPRODUCTION UPDATE
- The dynamics of nuclear receptors and nuclear receptor coregulators in the pathogenesis of endometriosis
- (2014) Sang Jun Han et al. HUMAN REPRODUCTION UPDATE
- Antenatal antioxidant treatment with melatonin to decrease newborn neurodevelopmental deficits and brain injury caused by fetal growth restriction
- (2014) Suzanne L. Miller et al. JOURNAL OF PINEAL RESEARCH
- Molecular mechanisms of epithelial–mesenchymal transition
- (2014) Samy Lamouille et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Effect of Melatonin on Tumor Growth and Angiogenesis in Xenograft Model of Breast Cancer
- (2014) Bruna Victorasso Jardim-Perassi et al. PLoS One
- A pilot double-blind randomised placebo-controlled dose-response trial assessing the effects of melatonin on infertility treatment (MIART): study protocol
- (2014) S. Fernando et al. BMJ Open
- Vascular endothelial growth factor C is increased in endometrium and promotes endothelial functions, vascular permeability and angiogenesis and growth of endometriosis
- (2013) Hui Xu et al. ANGIOGENESIS
- Melatonin inhibits the proliferation of human osteosarcoma cell line MG-63
- (2013) Lifeng Liu et al. BONE
- Inhibition of matrix metalloproteinase-9 and nuclear factor kappa B contribute to melatonin prevention of motility and invasiveness in HepG2 liver cancer cells
- (2013) Raquel Ordoñez et al. JOURNAL OF PINEAL RESEARCH
- Endometriosis: pathogenesis and treatment
- (2013) Paolo Vercellini et al. Nature Reviews Endocrinology
- Melatonin modulates aromatase activity and expression in endothelial cells
- (2013) VIRGINIA ALVAREZ-GARCÍA et al. ONCOLOGY REPORTS
- Efficacy of melatonin in the treatment of endometriosis: A phase II, randomized, double-blind, placebo-controlled trial
- (2013) André Schwertner et al. PAIN
- Eutopic Endometrium in Women with Endometriosis: Ground Zero for the Study of Implantation Defects
- (2013) Bruce Lessey et al. SEMINARS IN REPRODUCTIVE MEDICINE
- Melatonin augments hypothermic neuroprotection in a perinatal asphyxia model
- (2012) N. J. Robertson et al. BRAIN
- The expression of estrogen receptors as well as GREB1, c-MYC, and cyclin D1, estrogen-regulated genes implicated in proliferation, is increased in peritoneal endometriosis
- (2012) Chiara Pellegrini et al. FERTILITY AND STERILITY
- Pathogenesis and pathophysiology of endometriosis
- (2012) Richard O. Burney et al. FERTILITY AND STERILITY
- Epithelial to mesenchymal transition-like and mesenchymal to epithelial transition-like processes might be involved in the pathogenesis of pelvic endometriosis†
- (2012) Sachiko Matsuzaki et al. HUMAN REPRODUCTION
- Evaluation of a panel of 28 biomarkers for the non-invasive diagnosis of endometriosis
- (2012) A. Vodolazkaia et al. HUMAN REPRODUCTION
- Melatonin reduces lung oxidative stress in patients with chronic obstructive pulmonary disease: a randomized, double-blind, placebo-controlled study
- (2012) Antonio George de Matos Cavalcante et al. JOURNAL OF PINEAL RESEARCH
- Simultaneous modulation of COX-2, p300, Akt, and Apaf-1 signaling by melatonin to inhibit proliferation and induce apoptosis in breast cancer cells
- (2012) Jingshu Wang et al. JOURNAL OF PINEAL RESEARCH
- Circadian Gating of Epithelial-to-Mesenchymal Transition in Breast Cancer Cells Via Melatonin-Regulation of GSK3β
- (2012) Lulu Mao et al. MOLECULAR ENDOCRINOLOGY
- Green tea epigallocatechin-3-gallate inhibits angiogenesis and suppresses vascular endothelial growth factor C/vascular endothelial growth factor receptor 2 expression and signaling in experimental endometriosis in vivo
- (2011) Hui Xu et al. FERTILITY AND STERILITY
- The efficacy of melatonin administration on oocyte quality
- (2011) A. Sertaç Batıoğlu et al. GYNECOLOGICAL ENDOCRINOLOGY
- Melatonin improves the oocyte and the embryo in IVF patients with sleep disturbances, but does not improve the sleeping problems
- (2011) Ozlem Gun Eryilmaz et al. JOURNAL OF ASSISTED REPRODUCTION AND GENETICS
- The use of high-dose melatonin in liver resection is safe: first clinical experience
- (2011) Arash Nickkholgh et al. JOURNAL OF PINEAL RESEARCH
- Protective role of melatonin in progesterone production by human luteal cells
- (2011) Toshiaki Taketani et al. JOURNAL OF PINEAL RESEARCH
- Melatonin reduces LH, 17 beta-estradiol and induces differential regulation of sex steroid receptors in reproductive tissues during rat ovulation
- (2011) Luiz Gustavo A Chuffa et al. Reproductive Biology and Endocrinology
- Effects of pinealectomy and melatonin supplementation on endometrial explants in a rat model
- (2010) Onder Koc et al. European Journal of Obstetrics & Gynecology and Reproductive Biology
- Melatonin improves inflammation processes in liver of senescence-accelerated prone male mice (SAMP8)
- (2010) Sara Cuesta et al. EXPERIMENTAL GERONTOLOGY
- Chronic pelvic pain and endometriosis: translational evidence of the relationship and implications
- (2010) P. Stratton et al. HUMAN REPRODUCTION UPDATE
- Melatonin and vitamin D3 synergistically down-regulate Akt and MDM2 leading to TGFβ-1-dependent growth inhibition of breast cancer cells
- (2010) Sara Proietti et al. JOURNAL OF PINEAL RESEARCH
- Melatonin protects against endometriosis via regulation of matrix metalloproteinase-3 and an apoptotic pathway
- (2010) Sumit Paul et al. JOURNAL OF PINEAL RESEARCH
- Adjuvant use of melatonin for treatment of fibromyalgia
- (2010) Saad Abdul-Rehman Hussain et al. JOURNAL OF PINEAL RESEARCH
- International Union of Basic and Clinical Pharmacology. LXXV. Nomenclature, Classification, and Pharmacology of G Protein-Coupled Melatonin Receptors
- (2010) M. L. Dubocovich et al. PHARMACOLOGICAL REVIEWS
- Melatonin—A pleiotropic, orchestrating regulator molecule
- (2010) Rüdiger Hardeland et al. PROGRESS IN NEUROBIOLOGY
- Melatonin inhibits aromatase promoter expression by regulating cyclooxygenases expression and activity in breast cancer cells
- (2009) C Martínez-Campa et al. BRITISH JOURNAL OF CANCER
- Epithelial-Mesenchymal Transitions in Development and Disease
- (2009) Jean Paul Thiery et al. CELL
- Melatonin and serotonin regulate the release of insulin-like growth factor-I, oxytocin and progesterone by cultured human granulosa cells
- (2009) H.-J. Schaeffer et al. EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES
- The effects of letrozole and melatonin on surgically induced endometriosis in a rat model: a preliminary study
- (2009) Gazi Yildirim et al. FERTILITY AND STERILITY
- Non-invasive diagnosis of endometriosis based on a combined analysis of six plasma biomarkers
- (2009) A. Mihalyi et al. HUMAN REPRODUCTION
- Melatonin improves placental efficiency and birth weight and increases the placental expression of antioxidant enzymes in undernourished pregnancy
- (2009) Hans G. Richter et al. JOURNAL OF PINEAL RESEARCH
- The generation of an array of clonal, immortalized cell models from the rat hypothalamus: analysis of melatonin effects on kisspeptin and gonadotropin-inhibitory hormone neurons
- (2009) S. Gingerich et al. NEUROSCIENCE
- Regulation of breast cancer-associated aromatase promoters
- (2008) Dong Chen et al. CANCER LETTERS
- Shift Work, hCLOCK T3111C Polymorphism, and Endometriosis Risk
- (2008) Jennifer L. Marino et al. EPIDEMIOLOGY
- Matrix metalloproteinases 2 and 9, E-cadherin, and β-catenin expression in endometriosis, low-grade endometrial carcinoma and non-neoplastic eutopic endometrium
- (2008) Ruthy Shaco-Levy et al. European Journal of Obstetrics & Gynecology and Reproductive Biology
- Metalloproteinases, vascular endothelial growth factor, and angiopoietin 1 and 2 in eutopic and ectopic endometrium
- (2008) Costantino Di Carlo et al. FERTILITY AND STERILITY
- Diagnostic experience among 4,334 women reporting surgically diagnosed endometriosis
- (2008) Rebecca Greene et al. FERTILITY AND STERILITY
- NF-κB and epithelial to mesenchymal transition of cancer
- (2008) Chengyin Min et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Low urinary 6-sulphatoxymelatonin concentrations in acute migraine
- (2008) Marcelo Rodrigues Masruha et al. JOURNAL OF HEADACHE AND PAIN
- Role of melatonin in regulating matrix metalloproteinase-9 via tissue inhibitors of metalloproteinase-1 during protection against endometriosis
- (2008) Sumit Paul et al. JOURNAL OF PINEAL RESEARCH
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- (2008) Javier G. Pizarro et al. JOURNAL OF PINEAL RESEARCH
- Melatonin to prevent migraine or tension-type headache in children
- (2008) Silvia Miano et al. NEUROLOGICAL SCIENCES
- Melatonin and pregnancy in the human
- (2008) H TAMURA et al. REPRODUCTIVE TOXICOLOGY
- Melatonin in the skin: synthesis, metabolism and functions
- (2008) Andrzej Slominski et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- Regression of endometrial explants in a rat model of endometriosis treated with melatonin
- (2007) Mehmet Güney et al. FERTILITY AND STERILITY
- Oxidative stress impairs oocyte quality and melatonin protects oocytes from free radical damage and improves fertilization rate
- (2007) Hiroshi Tamura et al. JOURNAL OF PINEAL RESEARCH
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