TRPV4 in adipose tissue ameliorates diet-induced obesity by promoting white adipocyte browning

Loss of TRPV4 Cation Channel Inhibition of Macrophage Infiltration and Neovascularization in a Mouse Cornea

(2023) Takayoshi Sumioka et al.   LABORATORY INVESTIGATION

Adipose-tissue plasticity in health and disease

(2022) Alexander Sakers et al.   CELL

Inflammation in obesity, diabetes, and related disorders

(2022) Theresa V. Rohm et al.   IMMUNITY

PI3K/AKT Signaling Tips the Balance of Cytoskeletal Forces for Cancer Progression

(2022) Shuo Deng et al.   Cancers

Dysfunction of insulin-AKT-UCP1 signalling inhibits transdifferentiation of human and mouse white preadipocytes into brown-like adipocytes

(2022) Jie Pan et al.   Adipocyte

The inhibitor of κB kinase β (IKKβ) phosphorylates IκBα twice in a single binding event through a sequential mechanism

(2022) Anthony A. Stephenson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

TRPing to the Point of Clarity: Understanding the Function of the Complex TRPV4 Ion Channel

(2021) Trine L. Toft-Bertelsen et al.   Cells

Mice with Fabp4-Cre ablation of Arid5b are resistant to diet-induced obesity and hepatic steatosis

(2021) Robert H. Whitson et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

ADGRA1 negatively regulates energy expenditure and thermogenesis through both sympathetic nervous system and hypothalamus–pituitary–thyroid axis in male mice

(2021) Xiao-Hong Zhang et al.   Cell Death & Disease

Brown and beige adipose tissue regulate systemic metabolism through a metabolite interorgan signaling axis

(2021) Anna Whitehead et al.   Nature Communications

Gastric Sensory and Motor Functions and Energy Intake in Health and Obesity—Therapeutic Implications

(2021) Lizeth Cifuentes et al.   Nutrients

TRP Channels in Brain Tumors

(2021) Giorgia Chinigò et al.   Frontiers in Cell and Developmental Biology

The Transient Receptor Potential Vanilloid 4 Channel and Cardiovascular Disease Risk Factors

(2021) Kenichi Goto et al.   Frontiers in Physiology

Role of the TRPV Channels in the Endoplasmic Reticulum Calcium Homeostasis

(2020) Aurélien Haustrate et al.   Cells

TRPV4: A Physio and Pathophysiologically Significant Ion Channel

(2020) Tamara Rosenbaum et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

TET1 is a beige adipocyte-selective epigenetic suppressor of thermogenesis

(2020) Sneha Damal Villivalam et al.   Nature Communications

A Transcriptomic Analysis Reveals Novel Patterns of Gene Expression During 3T3-L1 Adipocyte Differentiation

(2020) Wuping Sun et al.   Frontiers in Molecular Biosciences

MiR-27b-3p Inhibition Enhances Browning of Epididymal Fat in High-Fat Diet Induced Obese Mice

(2019) Jing Yu et al.   Frontiers in Endocrinology

The Global Syndemic of Obesity, Undernutrition, and Climate Change: The Lancet Commission report

(2019) Boyd A Swinburn et al.   LANCET

Akt in cancer: Mediator and more

(2019) Sundaramoorthy Revathidevi et al.   SEMINARS IN CANCER BIOLOGY

Visceral and ectopic fat, atherosclerosis, and cardiometabolic disease: a position statement

(2019) Ian J Neeland et al.   Lancet Diabetes & Endocrinology

Downregulation of osteopontin inhibits browning of white adipose tissues through PI3K-AKT pathway in C57BL / 6 mice

(2019) Yi Lu et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Small molecules for fat combustion: targeting obesity

(2018) Jingxin Liu et al.   Acta Pharmaceutica Sinica B

Fabp4-Cre-mediated Sirt6 deletion impairs adipose tissue function and metabolic homeostasis in mice

(2017) Xiwen Xiong et al.   JOURNAL OF ENDOCRINOLOGY

ROS signaling under metabolic stress: cross-talk between AMPK and AKT pathway

(2017) Yang Zhao et al.   Molecular Cancer

Traveling from the hypothalamus to the adipose tissue: The thermogenic pathway

(2017) Cristina Contreras et al.   Redox Biology

FABP4-Cre Mediated Expression of Constitutively Active ChREBP Protects Against Obesity, Fatty Liver, and Insulin Resistance

(2015) Alli M. Nuotio-Antar et al.   ENDOCRINOLOGY

Apelin Enhances Brown Adipogenesis and Browning of White Adipocytes

(2015) Aung Than et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

PI3K/Akt is involved in brown adipogenesis mediated by growth differentiation factor-5 in association with activation of the Smad pathway

(2014) Eiichi Hinoi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Characterization of Cre recombinase models for the study of adipose tissue

(2014) Elise Jeffery et al.   Adipocyte

Increased susceptibility ofTrpv4-deficient mice to obesity and obesity-induced osteoarthritis with very high-fat diet

(2012) Christopher J O'Conor et al.   ANNALS OF THE RHEUMATIC DISEASES

TRPV4 Is a Regulator of Adipose Oxidative Metabolism, Inflammation, and Energy Homeostasis

(2012) Li Ye et al.   CELL

TRPV4 deficiency increases skeletal muscle metabolic capacity and resistance against diet-induced obesity

(2011) Tatsuya Kusudo et al.   JOURNAL OF APPLIED PHYSIOLOGY

Ectopic recombination in the central and peripheral nervous system byaP2/FABP4-Cremice: Implications for metabolism research

(2010) Katrin Martens et al.   FEBS LETTERS

Nuclear IKKβ Is an Adaptor Protein for IκBα Ubiquitination and Degradation in UV-Induced NF-κB Activation

(2010) Yoshihiro Tsuchiya et al.   MOLECULAR CELL

Transplantation of adipose tissue and stem cells: role in metabolism and disease

(2010) Thien T. Tran et al.   Nature Reviews Endocrinology

Chronic Peroxisome Proliferator-activated Receptor γ (PPARγ) Activation of Epididymally Derived White Adipocyte Cultures Reveals a Population of Thermogenically Competent, UCP1-containing Adipocytes Molecularly Distinct from Classic Brown Adipocytes

(2009) Natasa Petrovic et al.   JOURNAL OF BIOLOGICAL CHEMISTRY