TET1 is a beige adipocyte-selective epigenetic suppressor of thermogenesis

Loss of TLE3 promotes the mitochondrial program in beige adipocytes and improves glucose metabolism

(2019) Stephanie Pearson et al.   GENES & DEVELOPMENT

Sex-specific metabolic functions of adipose Lipocalin-2

(2019) Karthickeyan Chella Krishnan et al.   Molecular Metabolism

Warming Induces Significant Reprogramming of Beige, but Not Brown, Adipocyte Cellular Identity

(2018) Hyun Cheol Roh et al.   Cell Metabolism

The Common and Distinct Features of Brown and Beige Adipocytes

(2018) Kenji Ikeda et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Sin3A recruits Tet1 to the PAH1 domain via a highly conserved Sin3-Interaction Domain

(2018) Aditya Chandru et al.   Scientific Reports

EBF2 transcriptionally regulates brown adipogenesis via the histone reader DPF3 and the BAF chromatin remodeling complex

(2017) Suzanne N. Shapira et al.   GENES & DEVELOPMENT

OPA1 in Lipid Metabolism: Function of OPA1 in Lipolysis and Thermogenesis of Adipocytes

(2017) Dinh-Toi Chu et al.   HORMONE AND METABOLIC RESEARCH

TET-mediated hydroxymethylcytosine at the Pparγ locus is required for initiation of adipogenic differentiation

(2017) Y Yoo et al.   INTERNATIONAL JOURNAL OF OBESITY

Histone deacetylase 3 prepares brown adipose tissue for acute thermogenic challenge

(2017) Matthew J. Emmett et al.   NATURE

UCP1-independent signaling involving SERCA2b-mediated calcium cycling regulates beige fat thermogenesis and systemic glucose homeostasis

(2017) Kenji Ikeda et al.   NATURE MEDICINE

Zfp423 Maintains White Adipocyte Identity through Suppression of the Beige Cell Thermogenic Gene Program

(2016) Mengle Shao et al.   Cell Metabolism

Beige Adipocyte Maintenance Is Regulated by Autophagy-Induced Mitochondrial Clearance

(2016) Svetlana Altshuler-Keylin et al.   Cell Metabolism

AMPK/α-Ketoglutarate Axis Dynamically Mediates DNA Demethylation in the Prdm16 Promoter and Brown Adipogenesis

(2016) Qiyuan Yang et al.   Cell Metabolism

PdgfraandPdgfrbgenetically interact during craniofacial development

(2016) Neil McCarthy et al.   DEVELOPMENTAL DYNAMICS

Lysine-specific demethylase 1 promotes brown adipose tissue thermogenesis via repressing glucocorticoid activation

(2016) Xing Zeng et al.   GENES & DEVELOPMENT

Histone Deacetylase 1 (HDAC1) Negatively Regulates Thermogenic Program in Brown Adipocytes via Coordinated Regulation of Histone H3 Lysine 27 (H3K27) Deacetylation and Methylation

(2016) Fenfen Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Human thermogenic adipocytes: a reflection on types of adipocyte, developmental origin, and potential application

(2016) Dinh-Toi Chu et al.   JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY

Isoform Switch of TET1 Regulates DNA Demethylation and Mouse Development

(2016) Wenhao Zhang et al.   MOLECULAR CELL

Transcriptional and epigenetic control of brown and beige adipose cell fate and function

(2016) Takeshi Inagaki et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

LSD1 Interacts with Zfp516 to Promote UCP1 Transcription and Brown Fat Program

(2016) Audrey Sambeat et al.   Cell Reports

Non-catalytic roles for TET1 protein negatively regulating neuronal differentiation through srGAP3 in neuroblastoma cells

(2016) Jie Gao et al.   Protein & Cell

Dynamic DNA methylation landscape defines brown and white cell specificity during adipogenesis

(2016) Yen Ching Lim et al.   Molecular Metabolism

A Creatine-Driven Substrate Cycle Enhances Energy Expenditure and Thermogenesis in Beige Fat

(2015) Lawrence Kazak et al.   CELL

Brown and Beige Fat: Physiological Roles beyond Heat Generation

(2015) Shingo Kajimura et al.   Cell Metabolism

Tet2 is required to resolve inflammation by recruiting Hdac2 to specifically repress IL-6

(2015) Qian Zhang et al.   NATURE

Short-term cold acclimation improves insulin sensitivity in patients with type 2 diabetes mellitus

(2015) Mark J W Hanssen et al.   NATURE MEDICINE

An HDAC2-TET1 switch at distinct chromatin regions significantly promotes the maturation of pre-iPS to iPS cells

(2015) T. Wei et al.   NUCLEIC ACIDS RESEARCH

TET-catalyzed 5-methylcytosine hydroxylation is dynamically regulated by metabolites

(2014) Hui Yang et al.   CELL RESEARCH

Targeting adipose tissue via systemic gene therapy

(2014) S M O'Neill et al.   GENE THERAPY

Long-term parental methamphetamine exposure of mice influences behavior and hippocampal DNA methylation of the offspring

(2014) Y Itzhak et al.   MOLECULAR PSYCHIATRY

Characterization of Cre recombinase models for the study of adipose tissue

(2014) Elise Jeffery et al.   Adipocyte

UCP1 mRNA does not produce heat

(2013) Jan Nedergaard et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Improving Insulin Sensitivity With HDAC Inhibitor

(2013) J. Ye   DIABETES

EHMT1 controls brown adipose cell fate and thermogenesis through the PRDM16 complex

(2013) Haruya Ohno et al.   NATURE

TETonic shift: biological roles of TET proteins in DNA demethylation and transcription

(2013) William A. Pastor et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Progenitor Cells Identified by PDGFR-Alpha Expression in the Developing and Diseased Human Heart

(2013) James J.H. Chong et al.   STEM CELLS AND DEVELOPMENT

Genome-wide analysis identifies a functional association of Tet1 and Polycomb repressive complex 2 in mouse embryonic stem cells

(2013) Francesco Neri et al.   GENOME BIOLOGY

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

Beige Adipocytes Are a Distinct Type of Thermogenic Fat Cell in Mouse and Human

(2012) Jun Wu et al.   CELL

PTEN Loss in the Myf5 Lineage Redistributes Body Fat and Reveals Subsets of White Adipocytes that Arise from Myf5 Precursors

(2012) Joan Sanchez-Gurmaches et al.   Cell Metabolism

Inhibition of Class I Histone Deacetylases Unveils a Mitochondrial Signature and Enhances Oxidative Metabolism in Skeletal Muscle and Adipose Tissue

(2012) A. Galmozzi et al.   DIABETES

A Novel Adipose-Specific Gene Deletion Model Demonstrates Potential Pitfalls of Existing Methods

(2012) Shannon E. Mullican et al.   MOLECULAR ENDOCRINOLOGY

TET2 promotes histone O-GlcNAcylation during gene transcription

(2012) Qiang Chen et al.   NATURE

Human BAT Possesses Molecular Signatures That Resemble Beige/Brite Cells

(2012) Louis Z. Sharp et al.   PLoS One

TLE3 Is a Dual-Function Transcriptional Coregulator of Adipogenesis

(2011) Claudio J. Villanueva et al.   Cell Metabolism

Transcriptional Control of Adipose Lipid Handling by IRF4

(2011) Jun Eguchi et al.   Cell Metabolism

Desnutrin/ATGL Is Regulated by AMPK and Is Required for a Brown Adipose Phenotype

(2011) Maryam Ahmadian et al.   Cell Metabolism

Alternatively activated macrophages produce catecholamines to sustain adaptive thermogenesis

(2011) Khoa D. Nguyen et al.   NATURE

TET1 and hydroxymethylcytosine in transcription and DNA methylation fidelity

(2011) Kristine Williams et al.   NATURE

Tet Proteins Can Convert 5-Methylcytosine to 5-Formylcytosine and 5-Carboxylcytosine

(2011) S. Ito et al.   SCIENCE

Transcriptional control of preadipocyte determination by Zfp423

(2010) Rana K. Gupta et al.   NATURE

High Incidence of Metabolically Active Brown Adipose Tissue in Healthy Adult Humans: Effects of Cold Exposure and Adiposity

(2009) M. Saito et al.   DIABETES

Role of Jhdm2a in regulating metabolic gene expression and obesity resistance

(2009) Keisuke Tateishi et al.   NATURE

Identification and Importance of Brown Adipose Tissue in Adult Humans

(2009) Aaron M. Cypess et al.   NEW ENGLAND JOURNAL OF MEDICINE

Conversion of 5-Methylcytosine to 5-Hydroxymethylcytosine in Mammalian DNA by MLL Partner TET1

(2009) M. Tahiliani et al.   SCIENCE

PRDM16 controls a brown fat/skeletal muscle switch

(2008) Patrick Seale et al.   NATURE