Exploring Flow Procedures for Diazonium Formation

Continuous-Flow Process for the Synthesis of m-Nitrothioanisole

(2016) Zhiqun Yu et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

A multistep continuous flow synthesis machine for the preparation of pyrazoles via a metal-free amine-redox process

(2016) Jian-Siang Poh et al.   Reaction Chemistry & Engineering

Online quantitative mass spectrometry for the rapid adaptive optimisation of automated flow reactors

(2016) Nicholas Holmes et al.   Reaction Chemistry & Engineering

Continuous-Flow Technology-A Tool for the Safe Manufacturing of Active Pharmaceutical Ingredients

(2015) Bernhard Gutmann et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The synthesis of active pharmaceutical ingredients (APIs) using continuous flow chemistry

(2015) Marcus Baumann et al.   Beilstein Journal of Organic Chemistry

2- and 3-Stage temperature ramping for the direct synthesis of adipic acid in micro-flow packed-bed reactors

(2015) Minjing Shang et al.   CHEMICAL ENGINEERING JOURNAL

Amine-Terminated Monolayers on Carbon: Preparation, Characterization, and Coupling Reactions

(2015) Lita Lee et al.   LANGMUIR

Continuous-Flow Process for the Synthesis of 2-Ethylphenylhydrazine Hydrochloride

(2015) Zhiqun Yu et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

The Use of Gases in Flow Synthesis

(2015) Carl J. Mallia et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Flow Chemistry: Recent Developments in the Synthesis of Pharmaceutical Products

(2015) Riccardo Porta et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Flow chemistry as a discovery tool to access sp2–sp3 cross-coupling reactions via diazo compounds

(2015) Duc N. Tran et al.   Chemical Science

Handling diazonium salts in flow for organic and material chemistry

(2015) Nicolas Oger et al.   Organic Chemistry Frontiers

A Three-Minute Synthesis and Purification of Ibuprofen: Pushing the Limits of Continuous-Flow Processing

(2014) David R. Snead et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Multicomponent, Flow Diazotization/Mizoroki-Heck Coupling Protocol: Dispelling Myths about Working with Diazonium Salts

(2014) Kumara S. Nalivela et al.   CHEMISTRY-A EUROPEAN JOURNAL

Taming Hazardous Chemistry in Flow: The Continuous Processing of Diazo and Diazonium Compounds

(2014) Benjamin J. Deadman et al.   CHEMISTRY-A EUROPEAN JOURNAL

Continuous-Flow Heck–Matsuda Reaction: Homogeneous versus Heterogeneous Palladium Catalysts

(2014) Nicolas Oger et al.   JOURNAL OF ORGANIC CHEMISTRY

Eco-efficiency Analysis for Intensified Production of an Active Pharmaceutical Ingredient: A Case Study

(2014) Ivana Denčić et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Using Aryl Diazonium Salts in Palladium-Catalyzed Reactions under Safer Conditions

(2014) Nicolas Oger et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Continuous-Flow Synthesis of 1-Substituted Benzotriazoles from Chloronitrobenzenes and Amines in a CN Bond Formation/Hydrogenation/Diazotization/Cyclization Sequence

(2013) Mao Chen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Ethyl diazoacetate synthesis in flow

(2013) Mariëlle M E Delville et al.   Beilstein Journal of Organic Chemistry

Genetic Incorporation of a 2-Naphthol Group into Proteins for Site-Specific Azo Coupling

(2013) Shuo Chen et al.   BIOCONJUGATE CHEMISTRY

Flash chemistry: flow chemistry that cannot be done in batch

(2013) Jun-ichi Yoshida et al.   CHEMICAL COMMUNICATIONS

The role of flow in green chemistry and engineering

(2013) Stephen G. Newman et al.   GREEN CHEMISTRY

Continuous flow reactor for Balz–Schiemann reaction: a new procedure for the preparation of aromatic fluorides

(2013) Zhi-qun Yu et al.   TETRAHEDRON LETTERS

Flow chemistry approaches directed at improving chemical synthesis

(2013) Ian R. Baxendale et al.   Green Processing and Synthesis

The integration of flow reactors into synthetic organic chemistry

(2012) Ian R. Baxendale   JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY

Continuous Flow Synthesis. A Pharma Perspective

(2012) Laia Malet-Sanz et al.   JOURNAL OF MEDICINAL CHEMISTRY

CyclicSide-Chain Phenylazo Naphthalene Polymers: Enhanced Fluorescence Emission and Surface Relief Grating Formation

(2012) Hao Zhang et al.   MACROMOLECULAR RAPID COMMUNICATIONS

Continuous Multiple Liquid–Liquid Separation: Diazotization of Amino Acids in Flow

(2012) Dennis X. Hu et al.   ORGANIC LETTERS

Continuous Flow Production of Thermally Unstable Intermediates in a Microreactor with Inline IR-Analysis: Controlled Vilsmeier–Haack Formylation of Electron-Rich Arenes

(2012) Sebastiaan (Bas) A. M. W. van den Broek et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Telescoped Flow Process for the Syntheses of N-Aryl Pyrazoles

(2012) Bryan Li et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

A Continuous Kilogram-Scale Process for the Manufacture of o-Difluorobenzene

(2012) Zhiqun Yu et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Continuous flow reaction monitoring using an on-line miniature mass spectrometer

(2012) Duncan L. Browne et al.   RAPID COMMUNICATIONS IN MASS SPECTROMETRY

Nanoparticles of organosilane-based nitrite ionic liquid immobilized on silica for the diazotization of aniline derivatives and subsequent synthesis of azo dyes

(2011) Hassan Valizadeh et al.   DYES AND PIGMENTS

Diazotization of anilines and diazo coupling with a coupling component mediated by a polymer-supported sodium nitrite and a polymeric acid

(2011) Mohammad Ali Karimi Zarchi et al.   JOURNAL OF APPLIED POLYMER SCIENCE

Teflon AF-2400 mediated gas–liquid contact in continuous flow methoxycarbonylations and in-line FTIR measurement of CO concentration

(2011) Peter Koos et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Flow synthesis of organic azides and the multistep synthesis of imines and amines using a new monolithic triphenylphosphine reagent

(2011) Catherine J. Smith et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

A fully automated, multistep flow synthesis of 5-amino-4-cyano-1,2,3-triazoles

(2011) Catherine J. Smith et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Piecing together the puzzle: understanding a mild, metal free reduction method for the large scale synthesis of hydrazines

(2011) Duncan L. Browne et al.   TETRAHEDRON

Aryldiazonium silica sulfates as efficient reagents for Heck-type arylation reactions under mild conditions

(2011) Amin Zarei et al.   TETRAHEDRON LETTERS

Copper catalyzed Gomberg–Buchmann–Hey reaction using aryldiazonium tosylate

(2011) Ganesh U. Chaturbhuj et al.   TETRAHEDRON LETTERS

Hydrogenation in flow: Homogeneous and heterogeneous catalysis using Teflon AF-2400 to effect gas–liquid contact at elevated pressure

(2011) Matthew O'Brien et al.   Chemical Science

Synthesis and in vitro antiprotozoal activities of water-soluble, inexpensive phenothiazinium chlorides

(2010) Yue-Ting Lu et al.   DYES AND PIGMENTS

The flow synthesis of heterocycles for natural product and medicinal chemistry applications

(2010) Marcus Baumann et al.   MOLECULAR DIVERSITY

The continuous flow synthesis of butane-2,3-diacetal protected building blocks using microreactors

(2010) Catherine F. Carter et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Preparation of arylsulfonyl chlorides by chlorosulfonylation of in situ generated diazonium salts using a continuous flow reactor

(2010) Laia Malet-Sanz et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Flow Ozonolysis Using a Semipermeable Teflon AF-2400 Membrane To Effect Gas−Liquid Contact

(2010) Matthew O’Brien et al.   ORGANIC LETTERS

Second-Generation Process Research Towards Eletriptan: A Fischer Indole Approach

(2010) Christopher P. Ashcroft et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Prediction of acidity in acetonitrile solution with COSMO-RS

(2008) Frank Eckert et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

Unusually Stable, Versatile, and Pure Arenediazonium Tosylates: Their Preparation, Structures, and Synthetic Applicability

(2008) Victor D. Filimonov et al.   ORGANIC LETTERS

Heavy-Metal-Free Reduction Methodology for Large-Scale Synthesis Applicable to Heterocyclic and Arylhydrazines†

(2008) Timothy Norris et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT