Flash chemistry: flow chemistry that cannot be done in batch

Generation and Reactions of Pyridyllithiums via Br/Li Exchange Reactions Using Continuous Flow Microreactor Systems

(2013) Aiichiro Nagaki et al.   AUSTRALIAN JOURNAL OF CHEMISTRY

Applying Flow Chemistry: Methods, Materials, and Multistep Synthesis

(2013) D. Tyler McQuade et al.   JOURNAL OF ORGANIC CHEMISTRY

Enantioselective β-Arylation of Ketones Enabled by Lithiation/Borylation/1,4-Addition Sequence Under Flow Conditions

(2012) Wei Shu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Lithiation of 1,2-Dichloroethene in Flow Microreactors: Versatile Synthesis of Alkenes and Alkynes by Precise Residence-Time Control

(2012) Aiichiro Nagaki et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Flow synthesis of arylboronic esters bearing electrophilic functional groups and space integration with Suzuki–Miyaura coupling without intentionally added base

(2012) Aiichiro Nagaki et al.   CHEMICAL COMMUNICATIONS

Flash Generation of a Highly Reactive Pd Catalyst for Suzuki-Miyaura Coupling by Using a Flow Microreactor

(2012) Aiichiro Nagaki et al.   CHEMISTRY-A EUROPEAN JOURNAL

Cross-Coupling of Aryllithiums with Aryl and Vinyl Halides in Flow Microreactors

(2012) Aiichiro Nagaki et al.   Chemistry-An Asian Journal

Generation and Reactions of Vinyllithiums Using Flow Microreactor Systems

(2012) Aiichiro Nagaki et al.   Journal of Flow Chemistry

Cross-coupling in flow

(2011) Timothy Noël et al.   CHEMICAL SOCIETY REVIEWS

Diastereoselective Chain-Elongation Reactions Using Microreactors for Applications in Complex Molecule Assembly

(2011) Catherine F. Carter et al.   CHEMISTRY-A EUROPEAN JOURNAL

Flow microreactor synthesis of disubstituted pyridines from dibromopyridines via Br/Li exchange without using cryogenic conditions

(2011) Aiichiro Nagaki et al.   GREEN CHEMISTRY

Asymmetric Carbolithiation of Conjugated Enynes: A Flow Microreactor Enables the Use of Configurationally Unstable Intermediates before They Epimerize

(2011) Yutaka Tomida et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Teflon AF-2400 mediated gas–liquid contact in continuous flow methoxycarbonylations and in-line FTIR measurement of CO concentration

(2011) Peter Koos et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Perfluoroalkylation in flow microreactors: generation of perfluoroalkyllithiums in the presence and absence of electrophiles

(2011) Aiichiro Nagaki et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Continuous Photochemical Generation of Catalytically Active [CpRu]+Complexes from CpRu(η6-C6H6)PF6

(2011) Alicia C. Gutierrez et al.   ORGANIC LETTERS

A New Enabling Technology for Convenient Laboratory Scale Continuous Flow Processing at Low Temperatures

(2011) Duncan L. Browne et al.   ORGANIC LETTERS

Continuous Flow Processing of Slurries: Evaluation of an Agitated Cell Reactor

(2011) Duncan L. Browne et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Space Integration of Reactions: An Approach to Increase the Capability of Organic Synthesis

(2011) Jun-ichi Yoshida et al.   SYNLETT

A breakthrough method for the accurate addition of reagents in multi-step segmented flow processing

(2011) Heiko Lange et al.   Chemical Science

A flow-microreactor approach to protecting-group-free synthesis using organolithium compounds

(2011) Heejin Kim et al.   Nature Communications

Flash synthesis of TAC-101 and its analogues from 1,3,5-tribromobenzene using integrated flow microreactor systems

(2011) Aiichiro Nagaki et al.   RSC Advances

Cross-Coupling in a Flow Microreactor: Space Integration of Lithiation and Murahashi Coupling

(2010) Aiichiro Nagaki et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Integrated Microreactors for Reaction Automation: New Approaches to Reaction Development

(2010) Jonathan P. McMullen et al.   Annual Review of Analytical Chemistry

Flash chemistry: flow microreactor synthesis based on high-resolution reaction time control

(2010) Jun-Ichi Yoshida   CHEMICAL RECORD

Synthesis of micro and nanostructures in microfluidic systems

(2010) Samuel Marre et al.   CHEMICAL SOCIETY REVIEWS

Cationic Three-component Coupling Involving an Optically Active Enamine Derivative. From Time Integration to Space Integration of Reactions

(2010) Seiji Suga et al.   CHEMISTRY LETTERS

A Continuous Flow Process Using a Sequence of Microreactors with In-line IR Analysis for the Preparation of N,N-Diethyl-4-(3-fluorophenylpiperidin-4-ylidenemethyl)benzamide as a Potent and Highly Selective δ-Opioid Receptor Agonist

(2010) Zizheng Qian et al.   CHEMISTRY-A EUROPEAN JOURNAL

A Flow Microreactor System Enables Organolithium Reactions without Protecting Alkoxycarbonyl Groups

(2010) Aiichiro Nagaki et al.   CHEMISTRY-A EUROPEAN JOURNAL

Generation and Reactions of Oxiranyllithiums by Use of a Flow Microreactor System

(2010) Aiichiro Nagaki et al.   CHEMISTRY-A EUROPEAN JOURNAL

Automated Generation and Reactions of 3-Hydroxymethylindoles in Continuous-Flow Microreactors

(2010) Thomas Tricotet et al.   CHEMISTRY-A EUROPEAN JOURNAL

Flash Chemistry Extensively Optimized: High-Temperature Swern-Moffatt Oxidation in an Automated Microreactor Platform

(2010) Pieter J. Nieuwland et al.   Chemistry-An Asian Journal

Green and Sustainable Chemical Synthesis Using Flow Microreactors

(2010) Jun-ichi Yoshida et al.   ChemSusChem

Practical approach for macroporous structure embedded microfluidic system and the catalytic microchemical application

(2010) ZuoYi Xiao et al.   LAB ON A CHIP

Generation and reaction of cyano-substituted aryllithium compounds using microreactors

(2010) Aiichiro Nagaki et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

ReactIR Flow Cell: A New Analytical Tool for Continuous Flow Chemical Processing

(2010) Catherine F. Carter et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Photodimerization of Maleic Anhydride in a Microreactor Without Clogging

(2010) Tomoaki Horie et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Kinetic and Scale-Up Investigations of Epoxide Aminolysis in Microreactors at High Temperatures and Pressures

(2010) Nikolay Zaborenko et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Continuous flow multi-step organic synthesis

(2010) Damien Webb et al.   Chemical Science

Palladium-catalyzed amination reactions in flow: overcoming the challenges of clogging via acoustic irradiation

(2010) Timothy Noël et al.   Chemical Science

Dynamic Thermodynamic Resolution: Advantage by Separation of Equilibration and Resolution

(2009) Won Koo Lee et al.   ACCOUNTS OF CHEMICAL RESEARCH

Nitro-Substituted Aryl Lithium Compounds in Microreactor Synthesis: Switch between Kinetic and Thermodynamic Control

(2009) Aiichiro Nagaki et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Redox Economy in Organic Synthesis

(2009) Noah Z. Burns et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Controlling hazardous chemicals in microreactors: Synthesis with iodine azide

(2009) Johan C Brandt et al.   Beilstein Journal of Organic Chemistry

Expanding the scope of transformations of organoboron species: carbon–carbon bond formation with retention of configuration

(2009) Cathleen M. Crudden et al.   CHEMICAL COMMUNICATIONS

Generations and Reactions ofN-(t-Butylsulfonyl)aziridinyllithiums Using Microreactors

(2009) Aiichiro Nagaki et al.   CHEMISTRY LETTERS

Generation and Reactions of α-Silyloxiranyllithium in a Microreactor

(2009) Aiichiro Nagaki et al.   CHEMISTRY LETTERS

Oxiranyl Anion Methodology Using Microflow Systems

(2009) Aiichiro Nagaki et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Total Synthesis of Diverse Carbogenic Complexity within the Resveratrol Class from a Common Building Block

(2009) Scott A. Snyder et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Integrated microfluidic reactors

(2009) Wei-Yu Lin et al.   Nano Today

Synthesizing our future

(2009) Ryoji Noyori   Nature Chemistry

Protecting-group-free synthesis as an opportunity for invention

(2009) Ian S. Young et al.   Nature Chemistry

Synthesis of acetal protected building blocks using flow chemistry with flow I.R. analysis: preparation of butane-2,3-diacetal tartrates

(2009) Catherine F. Carter et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Concise Synthesis of Pauciflorol F Using a Larock Annulation

(2009) Jenna L. Jeffrey et al.   ORGANIC LETTERS

An Ozonolysis−Reduction Sequence for the Synthesis of Pharmaceutical Intermediates in Microstructured Devices

(2009) Sandra Hübner et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Heck reactions using segmented flow conditions

(2009) Batoul Ahmed-Omer et al.   TETRAHEDRON LETTERS

Aryllithium Compounds Bearing Alkoxycarbonyl Groups: Generation and Reactions Using a Microflow System

(2008) Aiichiro Nagaki et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Metal-Catalyzed Reactions of Organoboronic Acids and Esters

(2008) Norio Miyaura   BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN

Dimensionless number for identification of flow patterns inside a T-micromixer

(2008) A. Soleymani et al.   CHEMICAL ENGINEERING SCIENCE

α-Substituted α-Lithiated Oxiranes: Useful Reactive Intermediates

(2008) Vito Capriati et al.   CHEMICAL REVIEWS

Flash Chemistry: Fast Chemical Synthesis by Using Microreactors

(2008) Jun-ichi Yoshida et al.   CHEMISTRY-A EUROPEAN JOURNAL

Spurring Radical Reactions of Organic Halides with Tin Hydride and TTMSS Using Microreactors

(2008) Takahide Fukuyama et al.   ORGANIC LETTERS

Function-Oriented Synthesis, Step Economy, and Drug Design

(2007) Paul A. Wender et al.   ACCOUNTS OF CHEMICAL RESEARCH