Continuous-Flow Synthesis of 1-Substituted Benzotriazoles from Chloronitrobenzenes and Amines in a CN Bond Formation/Hydrogenation/Diazotization/Cyclization Sequence

Flow Chemistry - A Key Enabling Technology for (Multistep) Organic Synthesis

(2012) Jens Wegner et al.   ADVANCED SYNTHESIS & CATALYSIS

Continuous Synthesis and Purification by Direct Coupling of a Flow Reactor with Simulated Moving-Bed Chromatography

(2012) Alexander G. O'Brien et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Continuous-Flow Synthesis of the Anti-Malaria Drug Artemisinin

(2012) François Lévesque et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

On Being Green: Can Flow Chemistry Help?

(2012) Steven V. Ley   CHEMICAL RECORD

Continuous-Flow Synthesis of Monoarylated Acetaldehydes Using Aryldiazonium Salts

(2012) Natalia Chernyak et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Continuous Multiple Liquid–Liquid Separation: Diazotization of Amino Acids in Flow

(2012) Dennis X. Hu et al.   ORGANIC LETTERS

Design and preparation of new palladium precatalysts for C–C and C–N cross-coupling reactions

(2012) Nicholas C. Bruno et al.   Chemical Science

One-Flow, Multistep Synthesis of Nucleosides by Brønsted Acid-Catalyzed Glycosylation

(2011) Adam Sniady et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Highly N2-Selective Palladium-Catalyzed Arylation of 1,2,3-Triazoles

(2011) Satoshi Ueda et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Heterogeneous Catalytic Hydrogenation Reactions in Continuous-Flow Reactors

(2011) Muhammad Irfan et al.   ChemSusChem

Synopsis of Some Recent Tactical Application of Bioisosteres in Drug Design

(2011) Nicholas A. Meanwell   JOURNAL OF MEDICINAL CHEMISTRY

A fully automated, multistep flow synthesis of 5-amino-4-cyano-1,2,3-triazoles

(2011) Catherine J. Smith et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Pd-Catalyzed C−H Activation/C−N Bond Formation: A New Route to 1-Aryl-1H-benzotriazoles

(2011) Rapolu Kiran Kumar et al.   ORGANIC LETTERS

Hydrogenation in flow: Homogeneous and heterogeneous catalysis using Teflon AF-2400 to effect gas–liquid contact at elevated pressure

(2011) Matthew O'Brien et al.   Chemical Science

Accessing Stereochemically Rich Sultams via Microwave-assisted, Continuous-flow Organic Synthesis (MACOS) Scale-out

(2011) Michael G. Organ et al.   Journal of Flow Chemistry

Packed-Bed Reactors for Continuous-Flow CN Cross-Coupling

(2010) John R. Naber et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Real-Time Product Switching Using a Twin Catalyst System for the Hydrogenation of Furfural in Supercritical CO2

(2010) James G. Stevens et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Cross-Coupling in a Flow Microreactor: Space Integration of Lithiation and Murahashi Coupling

(2010) Aiichiro Nagaki et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A flow-based synthesis of Imatinib: the API of Gleevec

(2010) Mark D. Hopkin et al.   CHEMICAL COMMUNICATIONS

Indolyne and Aryne Distortions and Nucleophilic Regioselectivites

(2010) Paul H.-Y. Cheong et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A ligand-free copper (1) catalysed intramolecular N-arylation of diazoaminobenzenes in PEG-water: an expeditious protocol towards regiospecific 1-aryl benzotriazoles

(2010) Chhanda Mukhopadhyay et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

KMnO4-Mediated Oxidation as a Continuous Flow Process

(2010) Jörg Sedelmeier et al.   ORGANIC LETTERS

Photodimerization of Maleic Anhydride in a Microreactor Without Clogging

(2010) Tomoaki Horie et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Continuous flow multi-step organic synthesis

(2010) Damien Webb et al.   Chemical Science

Palladium-catalyzed amination reactions in flow: overcoming the challenges of clogging via acoustic irradiation

(2010) Timothy Noël et al.   Chemical Science

Multistep Synthesis Using Modular Flow Reactors: Bestmann-Ohira Reagent for the Formation of Alkynes and Triazoles

(2009) Ian R. Baxendale et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The Continuous-Flow Synthesis of Ibuprofen

(2009) Andrew R. Bogdan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis of Heterocycles Mediated by Benzotriazole. 1. Monocyclic Systems

(2009) Alan R. Katritzky et al.   CHEMICAL REVIEWS

TBAF-Assisted Copper-CatalyzedN-Arylation and Benzylation of Benzazoles with Aryl and Benzyl Halides under the Ligand/Base/ Solvent-Free Conditions

(2009) Hyung-Geun Lee et al.   JOURNAL OF ORGANIC CHEMISTRY

A Multistep Continuous-Flow System for Rapid On-Demand Synthesis of Receptor Ligands

(2009) Trine P. Petersen et al.   ORGANIC LETTERS

QSAR studies on BK channel activators

(2008) Alessio Coi et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Diaryl ether synthesis in supercritical carbon dioxide in batch and continuous flow modes

(2008) Jin-Kyun Lee et al.   CHEMICAL COMMUNICATIONS

Design, synthesis, and antifungal activity of triazole and benzotriazole derivatives

(2008) Zahra Rezaei et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Rapid Multistep Synthesis of 1,2,4-Oxadiazoles in a Single Continuous Microreactor Sequence

(2008) Daniel Grant et al.   JOURNAL OF ORGANIC CHEMISTRY

Benzyne Click Chemistry: Synthesis of Benzotriazoles from Benzynes and Azides

(2008) Feng Shi et al.   ORGANIC LETTERS

Synthesis of novel substituted 1,3-diaryl propenone derivatives and their antimalarial activity in vitro

(2007) Nidhi Mishra et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY