The flow synthesis of heterocycles for natural product and medicinal chemistry applications

A Palladium Wall Coated Microcapillary Reactor for Use in Continuous Flow Transfer Hydrogenation

(2010) Christian H. Hornung et al.   ADVANCED SYNTHESIS & CATALYSIS

A flow-based synthesis of Imatinib: the API of Gleevec

(2010) Mark D. Hopkin et al.   CHEMICAL COMMUNICATIONS

Welcome to Future Medicinal Chemistry

(2010) Iwao Ojima et al.   Future Medicinal Chemistry

Multiple Microcapillary Reactor for Organic Synthesis

(2010) Christian H. Hornung et al.   INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH

The continuous flow synthesis of butane-2,3-diacetal protected building blocks using microreactors

(2010) Catherine F. Carter et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

The application of flow microreactors to the preparation of a family of casein kinase I inhibitors

(2010) Francesco Venturoni et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Synthesis of Mycobacterial Triacylated Phosphatidylinositol Dimannoside Containing an Acyl Lipid Chain at 3-O of Inositol

(2010) Pratap S. Patil et al.   ORGANIC LETTERS

Flow Processing of Microwave-Assisted (Heterogeneous) Organic Reactions

(2010) Mark H. C. L. Dressen et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

ReactIR Flow Cell: A New Analytical Tool for Continuous Flow Chemical Processing

(2010) Catherine F. Carter et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Multistep Synthesis Using Modular Flow Reactors: Bestmann-Ohira Reagent for the Formation of Alkynes and Triazoles

(2009) Ian R. Baxendale et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Multi-Step Synthesis by Using Modular Flow Reactors: The Preparation of YneOnes and Their Use in Heterocycle Synthesis

(2009) Ian R. Baxendale et al.   CHEMISTRY-A EUROPEAN JOURNAL

Pd-EnCatTMTPP30 as a Catalyst for the Generation of Highly Functionalized Aryl- and Alkenyl-Substituted Acetylenes via Microwave-Assisted Sonogashira Type Reactions

(2009) Jörg Sedelmeier et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Relieving the first bottleneck in the drug discovery pipeline: using array technologies to rationalize membrane protein production

(2009) Nicklas Bonander et al.   Expert Review of Proteomics

Scavengers in full flow

(2009) Peter H. Seeberger   Nature Chemistry

The rise of fragment-based drug discovery

(2009) Christopher W. Murray et al.   Nature Chemistry

Synthesis of acetal protected building blocks using flow chemistry with flow I.R. analysis: preparation of butane-2,3-diacetal tartrates

(2009) Catherine F. Carter et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

An Ozonolysis−Reduction Sequence for the Synthesis of Pharmaceutical Intermediates in Microstructured Devices

(2009) Sandra Hübner et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Continuous Flow Nitration of Benzaldehyde

(2009) Amol A. Kulkarni et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Translating High-Temperature Microwave Chemistry to Scalable Continuous Flow Processes

(2009) Markus Damm et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Development of fluorination methods using continuous-flow microreactors

(2009) Marcus Baumann et al.   TETRAHEDRON

Trimethylaluminium mediated amide bond formation in a continuous flow microreactor as key to the synthesis of rimonabant and efaproxiral

(2008) Tomas Gustafsson et al.   CHEMICAL COMMUNICATIONS

Fluorination reactions in microreactors

(2008) Tomas Gustafsson et al.   CHEMICAL COMMUNICATIONS

Flash Chemistry: Fast Chemical Synthesis by Using Microreactors

(2008) Jun-ichi Yoshida et al.   CHEMISTRY-A EUROPEAN JOURNAL

Group Efficiency: A Guideline for Hits-to-Leads Chemistry

(2008) Marcel L. Verdonk et al.   ChemMedChem

The Changing Face of Organic Synthesis

(2008) Steven V. Ley et al.   CHIMIA

A Bifurcated Pathway to Thiazoles and Imidazoles Using a Modular Flow Microreactor

(2008) Ian R. Baxendale et al.   JOURNAL OF COMBINATORIAL CHEMISTRY

Application of Combinatorial Chemistry Science on Modern Drug Discovery

(2008) J. Phillip Kennedy et al.   JOURNAL OF COMBINATORIAL CHEMISTRY

Rapid Multistep Synthesis of 1,2,4-Oxadiazoles in a Single Continuous Microreactor Sequence

(2008) Daniel Grant et al.   JOURNAL OF ORGANIC CHEMISTRY

A modular flow reactor for performing Curtius rearrangements as a continuous flow process

(2008) Marcus Baumann et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Azide monoliths as convenient flow reactors for efficient Curtius rearrangement reactions

(2008) Marcus Baumann et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Enantiomer selective acylation of racemic alcohols by lipases in continuous-flow bioreactors

(2008) Csaba Csajági et al.   TETRAHEDRON-ASYMMETRY