Association of remnant cholesterol with frailty: findings from observational and Mendelian randomization analyses

Unraveling the metabolic underpinnings of frailty using multicohort observational and Mendelian randomization analyses

(2023) Jonathan K. L. Mak et al.   AGING CELL

Bias correction for inverse variance weighting Mendelian randomization

(2023) Ninon Mounier et al.   GENETIC EPIDEMIOLOGY

Remnant cholesterol, low-density lipoprotein cholesterol, and incident cardiovascular disease among Koreans: a national population-based study

(2023) Sang Jun Lee et al.   European Journal of Preventive Cardiology

A genome-wide association study of frailty identifies significant genetic correlation with neuropsychiatric, cardiovascular, and inflammation pathways

(2023) Yixuan Ye et al.   GeroScience

Discordance Between Standard Equations for Determination of LDL Cholesterol in Patients With Atherosclerosis

(2022) Aparna Sajja et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Frailty in rodents: models, underlying mechanisms, and management

(2022) Pan Liu et al.   AGEING RESEARCH REVIEWS

New insight into dyslipidemia‐induced cellular senescence in atherosclerosis

(2022) Qunyan Xiang et al.   BIOLOGICAL REVIEWS

Characterising metabolomic signatures of lipid-modifying therapies through drug target mendelian randomisation

(2022) Tom G. Richardson et al.   PLOS BIOLOGY

Remnant cholesterol and the risk of cardiovascular disease in type 2 diabetes: a nationwide longitudinal cohort study

(2022) Ji Hye Huh et al.   Cardiovascular Diabetology

A long-term obesogenic high-fat diet in mice partially dampens the anti-frailty benefits of late-life intermittent fasting

(2022) Yoko O. Henderson et al.   GeroScience

Secondhand smoke is positively associated with pre-frailty and frailty in non-smoking older adults

(2022) Zhenmei Fu et al.   Frontiers in Psychiatry

Using Mendelian Randomization to Improve the Design of Randomized Trials

(2021) Brian A. Ference et al.   Cold Spring Harbor Perspectives in Medicine

A genome‐wide association study of the frailty index highlights brain pathways in ageing

(2021) Janice L. Atkins et al.   AGING CELL

Prevalence of multidimensional frailty and pre-frailty in older people in different settings: A systematic review and meta-analysis

(2021) Nicola Veronese et al.   AGEING RESEARCH REVIEWS

Elevated remnant cholesterol increases the risk of peripheral artery disease, myocardial infarction, and ischaemic stroke: a cohort-based study

(2021) Benjamin Nilsson Wadström et al.   EUROPEAN HEART JOURNAL

A New Equation for Calculation of Low-Density Lipoprotein Cholesterol in Patients With Normolipidemia and/or Hypertriglyceridemia

(2020) Maureen Sampson et al.   JAMA Cardiology

Contribution of remnant cholesterol to cardiovascular risk

(2020) Anne Langsted et al.   JOURNAL OF INTERNAL MEDICINE

Postprandial triglyceride-rich lipoproteins-induced premature senescence of adipose-derived mesenchymal stem cells via the SIRT1/p53/Ac-p53/p21 axis through oxidative mechanism

(2020) Qun-yan Xiang et al.   Aging-US

Remnant Cholesterol, Not LDL Cholesterol, Is Associated With Incident Cardiovascular Disease

(2020) Olga Castañer et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

PhenoScanner V2: an expanded tool for searching human genotype–phenotype associations

(2019) Mihir A Kamat et al.   BIOINFORMATICS

Genetically-predicted life-long lowering of low-density lipoprotein cholesterol is associated with decreased frailty: A Mendelian randomization study in UK biobank

(2019) Qi Wang et al.   EBioMedicine

Frailty: implications for clinical practice and public health

(2019) Emiel O Hoogendijk et al.   LANCET

Determination of optimal cut-off points after a high-fat meal corresponding to fasting elevations of triglyceride and remnant cholesterol in Chinese subjects

(2019) Jin Xu et al.   Lipids in Health and Disease

Detection of widespread horizontal pleiotropy in causal relationships inferred from Mendelian randomization between complex traits and diseases

(2018) Marie Verbanck et al.   NATURE GENETICS

Orienting the causal relationship between imprecisely measured traits using GWAS summary data

(2017) Gibran Hemani et al.   PLoS Genetics

Development and validation of an electronic frailty index using routine primary care electronic health record data

(2016) Andrew Clegg et al.   AGE AND AGEING

Frailty in NHANES: Comparing the frailty index and phenotype

(2015) Joanna Blodgett et al.   ARCHIVES OF GERONTOLOGY AND GERIATRICS

The frailty phenotype and the frailty index: different instruments for different purposes

(2013) M. Cesari et al.   AGE AND AGEING

A New Equation to Estimate Glomerular Filtration Rate

(2013) Andrew S. Levey et al.   ANNALS OF INTERNAL MEDICINE

Comparison of a Novel Method vs the Friedewald Equation for Estimating Low-Density Lipoprotein Cholesterol Levels From the Standard Lipid Profile

(2013) Seth S. Martin et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Remnant cholesterol as a cause of ischemic heart disease: Evidence, definition, measurement, atherogenicity, high risk patients, and present and future treatment

(2013) Anette Varbo et al.   PHARMACOLOGY & THERAPEUTICS

Avoiding bias from weak instruments in Mendelian randomization studies

(2011) Stephen Burgess et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Power and instrument strength requirements for Mendelian randomization studies using multiple genetic variants

(2010) Brandon L Pierce et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

A standard procedure for creating a frailty index

(2008) Samuel D Searle et al.   BMC Geriatrics