Power and instrument strength requirements for Mendelian randomization studies using multiple genetic variants

Genome-wide Association Study of Vitamin B6, Vitamin B12, Folate, and Homocysteine Blood Concentrations

(2009) Toshiko Tanaka et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Common Variation in the β-Carotene 15,15′-Monooxygenase 1 Gene Affects Circulating Levels of Carotenoids: A Genome-wide Association Study

(2009) Luigi Ferrucci et al.   AMERICAN JOURNAL OF HUMAN GENETICS

A novel variant on chromosome 7q22.3 associated with mean platelet volume, counts, and function

(2009) N. Soranzo et al.   BLOOD

Meta-analysis of genome-wide association data identifies two loci influencing age at menarche

(2009) John R B Perry et al.   NATURE GENETICS

Genome-wide association studies identify loci associated with age at menarche and age at natural menopause

(2009) Chunyan He et al.   NATURE GENETICS

Genome-wide association study identifies sequence variants on 6q21 associated with age at menarche

(2009) Patrick Sulem et al.   NATURE GENETICS

Genetic variation in LIN28B is associated with the timing of puberty

(2009) Ken K Ong et al.   NATURE GENETICS

Genome-wide association study for early-onset and morbid adult obesity identifies three new risk loci in European populations

(2009) David Meyre et al.   NATURE GENETICS

Loci at chromosomes 13, 19 and 20 influence age at natural menopause

(2009) Lisette Stolk et al.   NATURE GENETICS

A large-scale genome-wide association study of Asian populations uncovers genetic factors influencing eight quantitative traits

(2009) Yoon Shin Cho et al.   NATURE GENETICS

Genome-wide association study identifies eight loci associated with blood pressure

(2009) Christopher Newton-Cheh et al.   NATURE GENETICS

Genome-wide association study of blood pressure and hypertension

(2009) Daniel Levy et al.   NATURE GENETICS

Plasma lipoproteins: genetic influences and clinical implications

(2009) Robert A. Hegele   NATURE REVIEWS GENETICS

Genome-Wide Association Analyses Identify SPOCK as a Key Novel Gene Underlying Age at Menarche

(2009) Yao-Zhong Liu et al.   PLoS Genetics

Instrumental Variable Analysis for Estimation of Treatment Effects With Dichotomous Outcomes

(2008) J. A. Rassen et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

Population-Based Genome-wide Association Studies Reveal Six Loci Influencing Plasma Levels of Liver Enzymes

(2008) Xin Yuan et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Polymorphisms of the HNF1A Gene Encoding Hepatocyte Nuclear Factor-1α are Associated with C-Reactive Protein

(2008) Alexander P. Reiner et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Loci Related to Metabolic-Syndrome Pathways Including LEPR,HNF1A, IL6R, and GCKR Associate with Plasma C-Reactive Protein: The Women's Genome Health Study

(2008) Paul M. Ridker et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Genome-wide Association Study Identifies Genes for Biomarkers of Cardiovascular Disease: Serum Urate and Dyslipidemia

(2008) Chris Wallace et al.   AMERICAN JOURNAL OF HUMAN GENETICS

A Genome-wide Association Study Identifies Three Loci Associated with Mean Platelet Volume

(2008) Christa Meisinger et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Accounting for ancestry: population substructure and genome-wide association studies

(2008) C. Tian et al.   HUMAN MOLECULAR GENETICS

Estimation Based on Case-Control Designs with Known Prevalence Probability

(2008) Mark J. van der Laan  

Adjusting for bias and unmeasured confounding in Mendelian randomization studies with binary responses

(2008) Tom M Palmer et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Association of three genetic loci with uric acid concentration and risk of gout: a genome-wide association study

(2008) Abbas Dehghan et al.   LANCET

Genome-wide association analysis of metabolic traits in a birth cohort from a founder population

(2008) Chiara Sabatti et al.   NATURE GENETICS

Common variants of FUT2 are associated with plasma vitamin B12 levels

(2008) Aditi Hazra et al.   NATURE GENETICS

Common variants at 30 loci contribute to polygenic dyslipidemia

(2008) Sekar Kathiresan et al.   NATURE GENETICS

SLC2A9 is a newly identified urate transporter influencing serum urate concentration, urate excretion and gout

(2008) Veronique Vitart et al.   NATURE GENETICS

SLC2A9 influences uric acid concentrations with pronounced sex-specific effects

(2008) Angela Döring et al.   NATURE GENETICS

Genome-wide association yields new sequence variants at seven loci that associate with measures of obesity

(2008) Gudmar Thorleifsson et al.   NATURE GENETICS

Variants in MTNR1B influence fasting glucose levels

(2008) Inga Prokopenko et al.   NATURE GENETICS

A variant near MTNR1B is associated with increased fasting plasma glucose levels and type 2 diabetes risk

(2008) Nabila Bouatia-Naji et al.   NATURE GENETICS

Six new loci associated with body mass index highlight a neuronal influence on body weight regulation

(2008) Cristen J Willer et al.   NATURE GENETICS

Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts

(2008) Yurii S Aulchenko et al.   NATURE GENETICS

A Polymorphism Within the G6PC2 Gene Is Associated with Fasting Plasma Glucose Levels

(2008) N. Bouatia-Naji et al.   SCIENCE

‘Mendelian randomization’ equals instrumental variable analysis with genetic instruments

(2008) George L. Wehby et al.   STATISTICS IN MEDICINE

Revealing the architecture of gene regulation: the promise of eQTL studies

(2008) Yoav Gilad et al.   TRENDS IN GENETICS

A Genome-Wide Association Study Identifies Protein Quantitative Trait Loci (pQTLs)

(2008) David Melzer et al.   PLoS Genetics

Inflammation, Insulin Resistance, and Diabetes—Mendelian Randomization Using CRP Haplotypes Points Upstream

(2008) Eric J Brunner et al.   PLOS MEDICINE

Mendelian randomization: Using genes as instruments for making causal inferences in epidemiology

(2007) Debbie A. Lawlor et al.   STATISTICS IN MEDICINE