A genome-wide association study of frailty identifies significant genetic correlation with neuropsychiatric, cardiovascular, and inflammation pathways
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Title
A genome-wide association study of frailty identifies significant genetic correlation with neuropsychiatric, cardiovascular, and inflammation pathways
Authors
Keywords
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Journal
GeroScience
Volume -, Issue -, Pages -
Publisher
Springer Science and Business Media LLC
Online
2023-03-27
DOI
10.1007/s11357-023-00771-z
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Note: Only part of the references are listed.- A genome‐wide association study of the frailty index highlights brain pathways in ageing
- (2021) Janice L. Atkins et al. AGING CELL
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- (2020) Masahiro Kameda et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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- The Incremental Health Care Costs of Frailty Among Home Care Recipients With and Without Dementia in Ontario, Canada
- (2019) Luke Mondor et al. MEDICAL CARE
- Polygenic prediction via Bayesian regression and continuous shrinkage priors
- (2019) Tian Ge et al. Nature Communications
- Body weight, frailty, and chronic pain in older adults: a cross-sectional study
- (2019) Cheng Chen et al. BMC Geriatrics
- Overexpression of MAP3K3 promotes tumour growth through activation of the NF-κB signalling pathway in ovarian carcinoma
- (2019) Ying Zhang et al. Scientific Reports
- Frailty is associated with elevated CRP trajectories and higher numbers of neutrophils and monocytes
- (2019) Leonard Daniël Samson et al. EXPERIMENTAL GERONTOLOGY
- Genome-wide association meta-analysis identifies five novel loci for age-related hearing impairment
- (2019) Andries Paul Nagtegaal et al. Scientific Reports
- Detection of widespread horizontal pleiotropy in causal relationships inferred from Mendelian randomization between complex traits and diseases
- (2018) Marie Verbanck et al. NATURE GENETICS
- The association between brain volume, cortical brain infarcts and physical frailty
- (2018) Ilse M.J. Kant et al. NEUROBIOLOGY OF AGING
- Frailty and the endocrine system
- (2018) Andrew Clegg et al. Lancet Diabetes & Endocrinology
- Shared biological pathways for frailty and cognitive impairment: A systematic review
- (2018) Lana Sargent et al. AGEING RESEARCH REVIEWS
- The UK Biobank resource with deep phenotyping and genomic data
- (2018) Clare Bycroft et al. NATURE
- Frailty Index associates with GRIN2B in two representative samples from the United States and the United Kingdom
- (2018) Krisztina Mekli et al. PLoS One
- Robust inference in summary data Mendelian randomization via the zero modal pleiotropy assumption
- (2017) Fernando Pires Hartwig et al. INTERNATIONAL JOURNAL OF EPIDEMIOLOGY
- Frailty in Older Adults Undergoing Aortic Valve Replacement
- (2017) Jonathan Afilalo et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Oxidative stress and frailty: A systematic review and synthesis of the best evidence
- (2017) Pinar Soysal et al. MATURITAS
- Functional mapping and annotation of genetic associations with FUMA
- (2017) Kyoko Watanabe et al. Nature Communications
- Systematic tissue-specific functional annotation of the human genome highlights immune-related DNA elements for late-onset Alzheimer’s disease
- (2017) Qiongshi Lu et al. PLoS Genetics
- Inflammation and frailty in the elderly: A systematic review and meta-analysis
- (2016) Pinar Soysal et al. AGEING RESEARCH REVIEWS
- Consistent Estimation in Mendelian Randomization with Some Invalid Instruments Using a Weighted Median Estimator
- (2016) Jack Bowden et al. GENETIC EPIDEMIOLOGY
- Glucose Levels and Risk of Frailty
- (2016) Oleg Zaslavsky et al. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
- A reference panel of 64,976 haplotypes for genotype imputation
- (2016) NATURE GENETICS
- Regulation of Cardiac Autonomic Nervous System Control across Frailty Statuses: A Systematic Review
- (2015) Saman Parvaneh et al. GERONTOLOGY
- Mendelian randomization with invalid instruments: effect estimation and bias detection through Egger regression
- (2015) J. Bowden et al. INTERNATIONAL JOURNAL OF EPIDEMIOLOGY
- Frailty in Older Adults: A Nationally Representative Profile in the United States
- (2015) Karen Bandeen-Roche et al. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
- A global reference for human genetic variation
- (2015) Richard A. Gibbs et al. NATURE
- Partitioning heritability by functional annotation using genome-wide association summary statistics
- (2015) Hilary K Finucane et al. NATURE GENETICS
- Efficient Bayesian mixed-model analysis increases association power in large cohorts
- (2015) Po-Ru Loh et al. NATURE GENETICS
- A Statistical Framework to Predict Functional Non-Coding Regions in the Human Genome Through Integrated Analysis of Annotation Data
- (2015) Qiongshi Lu et al. Scientific Reports
- MAGMA: Generalized Gene-Set Analysis of GWAS Data
- (2015) Christiaan A. de Leeuw et al. PLoS Computational Biology
- UK Biobank: An Open Access Resource for Identifying the Causes of a Wide Range of Complex Diseases of Middle and Old Age
- (2015) Cathie Sudlow et al. PLOS MEDICINE
- Fried phenotype of frailty: cross-sectional comparison of three frailty stages on various health domains
- (2015) Linda P. M. Op het Veld et al. BMC Geriatrics
- Second-generation PLINK: rising to the challenge of larger and richer datasets
- (2015) Christopher C Chang et al. GigaScience
- The prevalence and outcomes of frailty in older cancer patients: a systematic review
- (2014) C. Handforth et al. ANNALS OF ONCOLOGY
- Cardiovascular risk profile and frailty in a population-based study of older British men
- (2014) S E Ramsay et al. HEART
- Association between Hearing Impairment and Frailty in Older Adults
- (2014) Rebecca J. Kamil et al. JOURNAL OF THE AMERICAN GERIATRICS SOCIETY
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- (2010) Peter M. Abadir CLINICS IN GERIATRIC MEDICINE
- Common Inherited Variation in Mitochondrial Genes Is Not Enriched for Associations with Type 2 Diabetes or Related Glycemic Traits
- (2010) Ayellet V. Segrè et al. PLoS Genetics
- Comparing Models of Frailty: The Health and Retirement Study
- (2009) Christine T. Cigolle et al. JOURNAL OF THE AMERICAN GERIATRICS SOCIETY
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