Hydrophilic Interaction Liquid Chromatography at Subzero Temperature for Hydrogen–Deuterium Exchange Mass Spectrometry

HDX-MS performed on BtuB in E. coli outer membranes delineates the luminal domain’s allostery and unfolding upon B12 and TonB binding

(2022) Adam M. Zmyslowski et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Chromatography at −30 °C for Reduced Back-Exchange, Reduced Carryover, and Improved Dynamic Range for Hydrogen–Deuterium Exchange Mass Spectrometry

(2022) Kyle W. Anderson et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Post-HDX Deglycosylation of Fc Gamma Receptor IIIa Glycoprotein Enables HDX Characterization of Its Binding Interface with IgG

(2021) Nicole D. Wagner et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Recommendations for the Propagation of Uncertainty in Hydrogen Exchange-Mass Spectrometric Measurements

(2021) David D. Weis   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Probing Universal Protein Dynamics Using Hydrogen–Deuterium Exchange Mass Spectrometry-Derived Residue-Level Gibbs Free Energy

(2021) Jochem H. Smit et al.   ANALYTICAL CHEMISTRY

Advances in Hydrogen/Deuterium Exchange Mass Spectrometry and the Pursuit of Challenging Biological Systems

(2021) Ellie I. James et al.   CHEMICAL REVIEWS

Unified pH Measurements of Ethanol, Methanol, and Acetonitrile, and Their Mixtures with Water

(2021) Lisa Deleebeeck et al.   SENSORS

HDX-MS and MD Simulations Provide Evidence for Stabilization of the IgG1—FcγRIa (CD64a) Immune Complex Through Intermolecular Glycoprotein Bonds

(2021) Kyle W. Anderson et al.   JOURNAL OF MOLECULAR BIOLOGY

Quantitative Hydrogen/Deuterium Exchange Mass Spectrometry

(2021) Yoshitomo Hamuro   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Construction of a Dual Protease Column, Subzero (-30 oC) Chromatography System and Multi-channel Precision Temperature Controller for Hydrogen-Deuterium Exchange Mass Spectrometry

(2020) Jeffrey W. Hudgens   JOURNAL OF RESEARCH OF THE NATIONAL INSTITUTE OF STANDARDS AND TECHNOLOGY

High-throughput hydrogen deuterium exchange mass spectrometry (HDX-MS) coupled with subzero-temperature ultrahigh pressure liquid chromatography (UPLC) separation for complex sample analysis

(2020) Mulin Fang et al.   ANALYTICA CHIMICA ACTA

Interlaboratory Comparison of Hydrogen–Deuterium Exchange Mass Spectrometry Measurements of the Fab Fragment of NISTmAb

(2019) Jeffrey W. Hudgens et al.   ANALYTICAL CHEMISTRY

ExMS2: An Integrated Solution for Hydrogen-Deuterium Exchange Mass Spectrometry Data Analysis

(2019) Zhong-yuan Kan et al.   ANALYTICAL CHEMISTRY

Reference Parameters for Protein Hydrogen Exchange Rates

(2018) David Nguyen et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Epitope Mapping by HDX-MS Elucidates the Surface Coverage of Antigens Associated with High Blocking Efficiency of Antibodies to Birch Pollen Allergen

(2018) Qian Zhang et al.   ANALYTICAL CHEMISTRY

Predictive Liquid Chromatography of Peptides Based on Hydrophilic Interactions for Mass Spectrometry-Based Proteomics

(2017) A. A. Lobas et al.   JOURNAL OF ANALYTICAL CHEMISTRY

Experimental Measurement and Modeling of Vapor–Liquid Equilibrium for the Ternary System Water + Acetonitrile + Ethylene Glycol

(2017) Lianzhong Zhang et al.   JOURNAL OF CHEMICAL AND ENGINEERING DATA

Subzero Celsius separations in three-zone temperature controlled hydrogen deuterium exchange mass spectrometry

(2017) Thomas E. Wales et al.   JOURNAL OF CHROMATOGRAPHY A

Computational method allowing Hydrogen-Deuterium Exchange Mass Spectrometry at single amide Resolution

(2017) Chris Gessner et al.   Scientific Reports

Rapid Conformational Analysis of Protein Drugs in Formulation by Hydrogen/Deuterium Exchange Mass Spectrometry

(2016) Zeinab E. Nazari et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

A Retrospective Evaluation of the Use of Mass Spectrometry in FDA Biologics License Applications

(2016) Sarah Rogstad et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Analytical Aspects of Hydrogen Exchange Mass Spectrometry

(2015) John R. Engen et al.   Annual Review of Analytical Chemistry

Enhancing the Quality of H/D Exchange Measurements with Mass Spectrometry Detection in Disulfide-Rich Proteins Using Electron Capture Dissociation

(2014) Cedric E. Bobst et al.   ANALYTICAL CHEMISTRY

Applications of Hydrogen/Deuterium Exchange MS from 2012 to 2014

(2014) Gregory F. Pirrone et al.   ANALYTICAL CHEMISTRY

Physicochemical and Functional Comparability Between the Proposed Biosimilar Rituximab GP2013 and Originator Rituximab

(2013) Jan Visser et al.   BIODRUGS

Hydrogen/deuterium exchange mass spectrometry for probing higher order structure of protein therapeutics: methodology and applications

(2013) Hui Wei et al.   DRUG DISCOVERY TODAY

On-line comprehensive two dimensional separations of charged compounds using reversed-phase high performance liquid chromatography and hydrophilic interaction chromatography. Part II: Application to the separation of peptides

(2013) Amélie D’Attoma et al.   JOURNAL OF CHROMATOGRAPHY A

Protein hydrogen exchange at residue resolution by proteolytic fragmentation mass spectrometry analysis

(2013) Z.-Y. Kan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pepsin Immobilized on High-Strength Hybrid Particles for Continuous Flow Online Digestion at 10 000 psi

(2012) Joomi Ahn et al.   ANALYTICAL CHEMISTRY

Subzero Temperature Chromatography for Reduced Back-Exchange and Improved Dynamic Range in Amide Hydrogen/Deuterium Exchange Mass Spectrometry

(2012) John D. Venable et al.   ANALYTICAL CHEMISTRY

Improved Protein Hydrogen/Deuterium Exchange Mass Spectrometry Platform with Fully Automated Data Processing

(2012) Zhongqi Zhang et al.   ANALYTICAL CHEMISTRY

Evaluation of hydrophilic interaction chromatography (HILIC) versus C18 reversed-phase chromatography for targeted quantification of peptides by mass spectrometry

(2012) Romain Simon et al.   JOURNAL OF CHROMATOGRAPHY A

Polar Aprotic Modifiers for Chromatographic Separation and Back-Exchange Reduction for Protein Hydrogen/Deuterium Exchange Monitored by Fourier Transform Ion Cyclotron Resonance Mass Spectrometry

(2012) Santosh G. Valeja et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

HDX Workbench: Software for the Analysis of H/D Exchange MS Data

(2012) Bruce D. Pascal et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Minimizing Back Exchange in the Hydrogen Exchange-Mass Spectrometry Experiment

(2012) Benjamin T. Walters et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Platform Dependencies in Bottom-up Hydrogen/Deuterium Exchange Mass Spectrometry

(2012) Kyle M. Burns et al.   MOLECULAR & CELLULAR PROTEOMICS

A 2H nuclear magnetic resonance study of the state of water in neat silica and zwitterionic stationary phases and its influence on the chromatographic retention characteristics in hydrophilic interaction high-performance liquid chromatography

(2011) Erika Wikberg et al.   JOURNAL OF CHROMATOGRAPHY A

Retention behavior of peptides in hydrophilic-interaction chromatography

(2011) Martin Gilar et al.   JOURNAL OF CHROMATOGRAPHY A

Hydrogen Exchange Mass Spectrometry of Bacteriorhodopsin Reveals Light-Induced Changes in the Structural Dynamics of a Biomolecular Machine

(2011) Yan Pan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

ExMS: Data Analysis for HX-MS Experiments

(2011) Zhong-Yuan Kan et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Ligand-Dependent Perturbation of the Conformational Ensemble for the GPCR β2 Adrenergic Receptor Revealed by HDX

(2011) Graham M. West et al.   STRUCTURE

Online coupling of reverse-phase and hydrophilic interaction liquid chromatography for protein and glycoprotein characterization

(2010) Maggie P. Y. Lam et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Hydrophilic interaction LC of peptides: Columns comparison and clustering

(2010) Sylvia Van Dorpe et al.   JOURNAL OF SEPARATION SCIENCE

Determination of amide hydrogen exchange by mass spectrometry: A new tool for protein structure elucidation

(2010) Zhongqi Zhang et al.   PROTEIN SCIENCE

Hydrogen/Deuterium Exchange Reveals Distinct Agonist/Partial Agonist Receptor Dynamics within Vitamin D Receptor/Retinoid X Receptor Heterodimer

(2010) Jun Zhang et al.   STRUCTURE

H/D Exchange and Mass Spectrometry in the Studies of Protein Conformation and Dynamics: Is There a Need for a Top-Down Approach?

(2009) Igor A. Kaltashov et al.   ANALYTICAL CHEMISTRY

Hydrophilic interaction chromatography coupled to electrospray mass spectrometry for the separation of peptides and protein digests

(2009) Yuanzhong Yang et al.   JOURNAL OF CHROMATOGRAPHY A

Investigation of an on-line two-dimensional chromatographic approach for peptide analysis in plasma by LC–MS–MS

(2009) Ang Liu et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Serial coupling of reversed-phase and hydrophilic interaction liquid chromatography to broaden the elution window for the analysis of pharmaceutical compounds

(2008) Stefan Louw et al.   JOURNAL OF CHROMATOGRAPHY A

Fast reversed-phase liquid chromatography to reduce back exchange and increase throughput in H/D exchange monitored by FT-ICR mass spectrometry

(2008) Hui-Min Zhang et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY