Quantitative Hydrogen/Deuterium Exchange Mass Spectrometry

Recommendations for the Propagation of Uncertainty in Hydrogen Exchange-Mass Spectrometric Measurements

(2021) David D. Weis   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

The effects of intramolecular and intermolecular electrostatic repulsions on the stability and aggregation of NISTmAb revealed by HDX‐MS , DSC, and nanoDSF

(2021) Yoshitomo Hamuro et al.   PROTEIN SCIENCE

Tutorial: Chemistry of Hydrogen/Deuterium Exchange Mass Spectrometry

(2020) Yoshitomo Hamuro   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Interlaboratory Comparison of Hydrogen–Deuterium Exchange Mass Spectrometry Measurements of the Fab Fragment of NISTmAb

(2019) Jeffrey W. Hudgens et al.   ANALYTICAL CHEMISTRY

ExMS2: An Integrated Solution for Hydrogen-Deuterium Exchange Mass Spectrometry Data Analysis

(2019) Zhong-yuan Kan et al.   ANALYTICAL CHEMISTRY

Reliable identification of significant differences in differential HX-MS measurements using a hybrid significance testing approach

(2019) Tyler S Hageman et al.   ANALYTICAL CHEMISTRY

Recommendations for performing, interpreting and reporting hydrogen deuterium exchange mass spectrometry (HDX-MS) experiments

(2019) Glenn R. Masson et al.   NATURE METHODS

Evaluation of Hydrogen Exchange Mass Spectrometry as a Stability-Indicating Method for Formulation Excipient Screening for an IgG4 Monoclonal Antibody

(2018) Ronald T. Toth et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Determination of Backbone Amide Hydrogen Exchange Rates of Cytochrome c Using Partially Scrambled Electron Transfer Dissociation Data

(2018) Yoshitomo Hamuro et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Optimization of Feasibility Stage for Hydrogen/Deuterium Exchange Mass Spectrometry

(2018) Yoshitomo Hamuro et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Reference Parameters for Protein Hydrogen Exchange Rates

(2018) David Nguyen et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

High-Resolution HDX-MS of Cytochrome c Using Pepsin/Fungal Protease Type XIII Mixed Bed Column

(2018) Yoshitomo Hamuro et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Determination of Equine Cytochrome c Backbone Amide Hydrogen/Deuterium Exchange Rates by Mass Spectrometry Using a Wider Time Window and Isotope Envelope

(2017) Yoshitomo Hamuro   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Regio-Selective Intramolecular Hydrogen/Deuterium Exchange in Gas-Phase Electron Transfer Dissociation

(2017) Yoshitomo Hamuro   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

The Area Between Exchange Curves as a Measure of Conformational Differences in Hydrogen-Deuterium Exchange Mass Spectrometry Studies

(2017) Sharlyn J. Mazur et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Characterization of Pre-F-GCN4t, a Modified Human Respiratory Syncytial Virus Fusion Protein Stabilized in a Noncleaved Prefusion Conformation

(2017) Normand Blais et al.   JOURNAL OF VIROLOGY

The case for defined protein folding pathways

(2017) S. Walter Englander et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Conformational changes in intact dengue virus reveal serotype-specific expansion

(2017) Xin-Xiang Lim et al.   Nature Communications

Two-Site Evaluation of the Repeatability and Precision of an Automated Dual-Column Hydrogen/Deuterium Exchange Mass Spectrometry Platform

(2016) David J. Cummins et al.   ANALYTICAL CHEMISTRY

A Residue-Resolved Bayesian Approach to Quantitative Interpretation of Hydrogen–Deuterium Exchange from Mass Spectrometry: Application to Characterizing Protein–Ligand Interactions

(2016) Daniel J. Saltzberg et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Measuring the Hydrogen/Deuterium Exchange of Proteins at High Spatial Resolution by Mass Spectrometry: Overcoming Gas-Phase Hydrogen/Deuterium Scrambling

(2014) Kasper D. Rand et al.   ACCOUNTS OF CHEMICAL RESEARCH

Aspartic Protease Nepenthesin-1 as a Tool for Digestion in Hydrogen/Deuterium Exchange Mass Spectrometry

(2014) Alan Kadek et al.   ANALYTICAL CHEMISTRY

Correlations between changes in conformational dynamics and physical stability in a mutant IgG1 mAb engineered for extended serum half-life

(2014) Ranajoy Majumdar et al.   mAbs

Structure of the meningococcal vaccine antigen NadA and epitope mapping of a bactericidal antibody

(2014) Enrico Malito et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The nature of protein folding pathways

(2014) S. Walter Englander et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Effects of Desialylation on Human α1-Acid Glycoprotein–Ligand Interactions

(2013) Richard Y.-C. Huang et al.   BIOCHEMISTRY

Effects of Salts from the Hofmeister Series on the Conformational Stability, Aggregation Propensity, and Local Flexibility of an IgG1 Monoclonal Antibody

(2013) Ranajoy Majumdar et al.   BIOCHEMISTRY

Peptide–Column Interactions and Their Influence on Back Exchange Rates in Hydrogen/Deuterium Exchange-MS

(2013) Joey G. Sheff et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Protein hydrogen exchange at residue resolution by proteolytic fragmentation mass spectrometry analysis

(2013) Z.-Y. Kan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Probing protein interactions with hydrogen/deuterium exchange and mass spectrometry—A review

(2012) Andrew J. Percy et al.   ANALYTICA CHIMICA ACTA

Improved Protein Hydrogen/Deuterium Exchange Mass Spectrometry Platform with Fully Automated Data Processing

(2012) Zhongqi Zhang et al.   ANALYTICAL CHEMISTRY

Mapping of discontinuous conformational epitopes by amide hydrogen/deuterium exchange mass spectrometry and computational docking

(2012) Deepangi Pandit et al.   JOURNAL OF MOLECULAR RECOGNITION

Minimizing Back Exchange in the Hydrogen Exchange-Mass Spectrometry Experiment

(2012) Benjamin T. Walters et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Platform Dependencies in Bottom-up Hydrogen/Deuterium Exchange Mass Spectrometry

(2012) Kyle M. Burns et al.   MOLECULAR & CELLULAR PROTEOMICS

Tracking Hydrogen/Deuterium Exchange at Glycan Sites in Glycoproteins by Mass Spectrometry

(2011) M. Guttman et al.   ANALYTICAL CHEMISTRY

Differential hydrogen/deuterium exchange mass spectrometry analysis of protein–ligand interactions

(2011) Michael J Chalmers et al.   Expert Review of Proteomics

Automated Hydrogen/Deuterium Exchange Electron Transfer Dissociation High Resolution Mass Spectrometry Measured at Single-Amide Resolution

(2011) Rachelle R. Landgraf et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

ExMS: Data Analysis for HX-MS Experiments

(2011) Zhong-Yuan Kan et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Many Overlapping Peptides for Protein Hydrogen Exchange Experiments by the Fragment Separation-Mass Spectrometry Method

(2011) Leland Mayne et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Determination of amide hydrogen exchange by mass spectrometry: A new tool for protein structure elucidation

(2010) Zhongqi Zhang et al.   PROTEIN SCIENCE

Expansion of time window for mass spectrometric measurement of amide hydrogen/deuterium exchange reactions

(2010) Stephen J. Coales et al.   RAPID COMMUNICATIONS IN MASS SPECTROMETRY

Characterization of IgG1 Conformation and Conformational Dynamics by Hydrogen/Deuterium Exchange Mass Spectrometry

(2009) Damian Houde et al.   ANALYTICAL CHEMISTRY

Analysis of Protein Conformation and Dynamics by Hydrogen/Deuterium Exchange MS

(2009) John R. Engen   ANALYTICAL CHEMISTRY

A Common Property of Amyotrophic Lateral Sclerosis-associated Variants

(2009) Kathleen S. Molnar et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structure of IL-17A in Complex with a Potent, Fully Human Neutralizing Antibody

(2009) Stefan Gerhardt et al.   JOURNAL OF MOLECULAR BIOLOGY

Investigating alternative acidic proteases for H/D exchange coupled to mass spectrometry: Plasmepsin 2 but not plasmepsin 4 is active under quenching conditions

(2009) Julien Marcoux et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Helical structure and stability in human apolipoprotein A-I by hydrogen exchange and mass spectrometry

(2009) Palaniappan Sevugan Chetty et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Epitope mapping by amide hydrogen/deuterium exchange coupled with immobilization of antibody, on-line proteolysis, liquid chromatography and mass spectrometry

(2009) Stephen J. Coales et al.   RAPID COMMUNICATIONS IN MASS SPECTROMETRY

Recombinant immobilized rhizopuspepsin as a new tool for protein digestion in hydrogen/deuterium exchange mass spectrometry

(2009) Martial Rey et al.   RAPID COMMUNICATIONS IN MASS SPECTROMETRY

Electron Capture Dissociation Proceeds with a Low Degree of Intramolecular Migration of Peptide Amide Hydrogens

(2008) Kasper D. Rand et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Effects of electrospray capillary temperature on amide hydrogen exchange

(2008) Stephen J. Coales et al.   RAPID COMMUNICATIONS IN MASS SPECTROMETRY

Specificity of immobilized porcine pepsin in H/D exchange compatible conditions

(2008) Yoshitomo Hamuro et al.   RAPID COMMUNICATIONS IN MASS SPECTROMETRY