The novel HS-mimetic, Tet-29, regulates immune cell trafficking across barriers of the CNS during inflammation

Low sulfated heparan sulfate mimetic differentially affects repair in immune‐mediated and toxin‐induced experimental models of demyelination

(2023) Susan L. Lindsay et al.   GLIA

Synthesis of Novel Glycolipid Mimetics of Heparan Sulfate and Their Application in Colorectal Cancer Treatment in a Mouse Model

(2022) Sam Spijkers‐Shaw et al.   Chemistry-An Asian Journal

Heparanome-mediated rescue of oligodendrocyte progenitor quiescence following inflammatory demyelination

(2021) Darpan Saraswat et al.   JOURNAL OF NEUROSCIENCE

CellProfiler 4: improvements in speed, utility and usability

(2021) David R. Stirling et al.   BMC BIOINFORMATICS

Glycocalyx Impairment in Vascular Disease: Focus on Inflammation

(2021) Jing Qu et al.   Frontiers in Cell and Developmental Biology

Sex Differences in EAE Reveal Common and Distinct Cellular and Molecular Components

(2020) Jack Wiedrick et al.   CELLULAR IMMUNOLOGY

Cell-surface heparan sulfate proteoglycans as multifunctional integrators of signaling in cancer

(2020) Nourhan Hassan et al.   CELLULAR SIGNALLING

The Role of Heparan Sulfate in Inflammation, and the Development of Biomimetics as Anti-Inflammatory Strategies

(2018) Brooke L. Farrugia et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

Dendrimer Heparan Sulfate Glycomimetics: Potent Heparanase Inhibitors for Anticancer Therapy

(2018) Olga V. Zubkova et al.   ACS Chemical Biology

Heparanase: From basic research to therapeutic applications in cancer and inflammation

(2016) Israel Vlodavsky et al.   DRUG RESISTANCE UPDATES

Mechanisms of heparanase inhibitors in cancer therapy

(2016) Benjamin Heyman et al.   EXPERIMENTAL HEMATOLOGY

Heparanase regulation of cancer, autophagy and inflammation: new mechanisms and targets for therapy

(2016) Ralph D. Sanderson et al.   FEBS Journal

Animal models of Multiple Sclerosis

(2015) Claudio Procaccini et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Early Treatment with Anti-VLA-4 mAb Can Prevent the Infiltration and/or Development of Pathogenic CD11b+CD4+ T Cells in the CNS during Progressive EAE

(2014) John E. Mindur et al.   PLoS One

The choroid plexus: a comprehensive review of its history, anatomy, function, histology, embryology, and surgical considerations

(2013) Martin M. Mortazavi et al.   CHILDS NERVOUS SYSTEM

Natalizumab Therapy for Multiple Sclerosis

(2013) Jeremy Chataway et al.   Neurotherapeutics

Epithelial V-Like Antigen Mediates Efficacy of Anti-Alpha4 Integrin Treatment in a Mouse Model of Multiple Sclerosis

(2013) Erik Wright et al.   PLoS One

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

Capture, crawl, cross: the T cell code to breach the blood–brain barriers

(2012) Britta Engelhardt et al.   TRENDS IN IMMUNOLOGY

Cell trafficking through the choroid plexus

(2012) Rick B. Meeker et al.   Cell Adhesion & Migration

Experimental autoimmune encephalomyelitis (EAE) as a model for multiple sclerosis (MS)

(2011) Cris S Constantinescu et al.   BRITISH JOURNAL OF PHARMACOLOGY

How do immune cells overcome the blood-brain barrier in multiple sclerosis?

(2011) Catherine Larochelle et al.   FEBS LETTERS

Heparan sulfate and heparanase play key roles in mouse β cell survival and autoimmune diabetes

(2011) Andrew F. Ziolkowski et al.   JOURNAL OF CLINICAL INVESTIGATION

Natalizumab treatment for multiple sclerosis: updated recommendations for patient selection and monitoring

(2011) Ludwig Kappos et al.   LANCET NEUROLOGY

IL-17 receptor signaling and T helper 17-mediated autoimmune demyelinating disease

(2011) Jarod Zepp et al.   TRENDS IN IMMUNOLOGY

Heparan Sulfate Proteoglycans

(2011) S. Sarrazin et al.   Cold Spring Harbor Perspectives in Biology

T cells in multiple sclerosis and experimental autoimmune encephalomyelitis

(2010) J. M. Fletcher et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Differential Roles for Endothelial ICAM-1, ICAM-2, and VCAM-1 in Shear-Resistant T Cell Arrest, Polarization, and Directed Crawling on Blood-Brain Barrier Endothelium

(2010) O. Steiner et al.   JOURNAL OF IMMUNOLOGY

Blood–brain barrier disruption and enhanced vascular permeability in the multiple sclerosis model EAE

(2010) Jami Bennett et al.   JOURNAL OF NEUROIMMUNOLOGY

Natalizumab-associated progressive multifocal leukoencephalopathy in patients with multiple sclerosis: lessons from 28 cases

(2010) David B Clifford et al.   LANCET NEUROLOGY

The PG500 series: novel heparan sulfate mimetics as potent angiogenesis and heparanase inhibitors for cancer therapy

(2009) K. Dredge et al.   INVESTIGATIONAL NEW DRUGS

Initiation and Progression of Axonopathy in Experimental Autoimmune Encephalomyelitis

(2009) A. M. Soulika et al.   JOURNAL OF NEUROSCIENCE

C-C chemokine receptor 6–regulated entry of TH-17 cells into the CNS through the choroid plexus is required for the initiation of EAE

(2009) Andrea Reboldi et al.   NATURE IMMUNOLOGY

Dramatic regulation of heparanase activity and angiogenesis gene expression in synovium from patients with rheumatoid arthritis

(2008) Rachel W. Li et al.   ARTHRITIS AND RHEUMATISM

The blood-brain barrier in brain homeostasis and neurological diseases

(2008) Nicolas Weiss et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES