Flavone-based dual PARP-Tubulin inhibitor manifesting efficacy against endometrial cancer
Published 2023 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Flavone-based dual PARP-Tubulin inhibitor manifesting efficacy against endometrial cancer
Authors
Keywords
-
Journal
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
Volume 38, Issue 1, Pages -
Publisher
Informa UK Limited
Online
2023-11-03
DOI
10.1080/14756366.2023.2276665
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Complete Pathologic Response to PARP Inhibitor Olaparib in a Patient with Stage IVB Recurrent Endometrioid Endometrial Adenocarcinoma
- (2023) Rosemary Noel Senguttuvan et al. Journal of Clinical Medicine
- Identification of a dual FLT3 and MNK2 inhibitor for acute myeloid leukemia treatment using a structure-based virtual screening approach
- (2022) Shih-Chung Yen et al. BIOORGANIC CHEMISTRY
- Cancer statistics in China and United States, 2022: profiles, trends, and determinants
- (2022) Changfa Xia et al. CHINESE MEDICAL JOURNAL
- Spirulina phycocyanin extract and its active components suppress epithelial-mesenchymal transition process in endometrial cancer via targeting TGF-beta1/SMAD4 signaling pathway
- (2022) Hsin-Yuan Chen et al. BIOMEDICINE & PHARMACOTHERAPY
- Endometrial Cancer Detection Using a Cervical DNA Methylation Assay (MPap) in Women with Abnormal Uterine Bleeding: A Multicenter Hospital-Based Validation Study
- (2022) Kuo-Chang Wen et al. Cancers
- Heterogeneity of outcomes of endometrial cancer patients included in prospective clinical trials
- (2022) Ryan M. Boone et al. GYNECOLOGIC ONCOLOGY
- Multi-therapies Based on PARP Inhibition: Potential Therapeutic Approaches for Cancer Treatment
- (2022) Jie Zhang et al. Journal of Medicinal Chemistry
- Adlay Testa (Coix lachryma-jobi L. var. Ma-yuen Stapf.) Ethanolic Extract and Its Active Components Exert Anti-Proliferative Effects on Endometrial Cancer Cells via Cell Cycle Arrest
- (2021) Yun-Ju Huang et al. MOLECULES
- The PARP Enzyme Family and the Hallmarks of Cancer Part 1. Cell Intrinsic Hallmarks
- (2021) Máté A. Demény et al. Cancers
- Discovery of Novel Apigenin–Piperazine Hybrids as Potent and Selective Poly (ADP-Ribose) Polymerase-1 (PARP-1) Inhibitors for the Treatment of Cancer
- (2021) Huan Long et al. JOURNAL OF MEDICINAL CHEMISTRY
- Hydroxychloroquine (HCQ) Modulates Autophagy and Oxidative DNA Damage Stress in Hepatocellular Carcinoma to Overcome Sorafenib Resistance via TLR9/SOD1/hsa-miR-30a-5p/Beclin-1 Axis
- (2021) Ming-Yao Chen et al. Cancers
- Discovery of a Dual Tubulin and Poly(ADP-Ribose) Polymerase-1 Inhibitor by Structure-Based Pharmacophore Modeling, Virtual Screening, Molecular Docking, and Biological Evaluation
- (2021) Lufeng Zheng et al. JOURNAL OF MEDICINAL CHEMISTRY
- Autophagy Upregulates miR-449a Expression to Suppress Progression of Colorectal Cancer
- (2021) Sheng-Hui Lan et al. Frontiers in Oncology
- Pilot Study to Establish a Novel Five-Gene Biomarker Panel for Predicting Lymph Node Metastasis in Patients With Early Stage Endometrial Cancer
- (2020) Chia-Yen Huang et al. Frontiers in Oncology
- Targeted PARP Inhibition Combined with FGFR1 Blockade is Synthetically Lethal to Malignant Cells in Patients with Pancreatic Cancer
- (2020) Shiue-Wei Lai et al. Cells
- Cancers in Taiwan: Practical insight from epidemiology, treatments, biomarkers, and cost
- (2019) Chun-Nan Kuo et al. JOURNAL OF THE FORMOSAN MEDICAL ASSOCIATION
- Molecular Mechanisms Underlying Yatein-Induced Cell-Cycle Arrest and Microtubule Destabilization in Human Lung Adenocarcinoma Cells
- (2019) Shang-Tse Ho et al. Cancers
- Combined genetic mutations and DNA-methylated genes as biomarkers for endometrial cancer detection from cervical scrapings
- (2019) Phui-Ly Liew et al. Clinical Epigenetics
- A New Histone Deacetylase Inhibitor Enhances Radiation Sensitivity through the Induction of Misfolded Protein Aggregation and Autophagy in Triple-Negative Breast Cancer
- (2019) Hui-Wen Chiu et al. Cancers
- The feasibility of detecting endometrial and ovarian cancer using DNA methylation biomarkers in cervical scrapings
- (2018) Cheng-Chang Chang et al. Journal of Gynecologic Oncology
- Women with adenomyosis are at higher risks of endometrial and thyroid cancers: A population-based historical cohort study
- (2018) Chih-Ching Yeh et al. PLoS One
- Design of Diarylheptanoid Derivatives as Dual Inhibitors Against Class IIa Histone Deacetylase and β-amyloid Aggregation
- (2018) Liang-Chieh Chen et al. Frontiers in Pharmacology
- Resveratrol-induced autophagy and apoptosis in cisplatin-resistant human oral cancer CAR cells: A key role of AMPK and Akt/mTOR signaling
- (2017) Chao-Hsiang Chang et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- Autophagy-inducing effect of pterostilbene: A prospective therapeutic/preventive option for skin diseases
- (2017) Rong-Jane Chen et al. JOURNAL OF FOOD AND DRUG ANALYSIS
- Methoxyphenyl chalcone sensitizes aggressive epithelial cancer to cisplatin through apoptosis induction and cancer stem cell eradication
- (2017) Yu-kai Su et al. TUMOR BIOLOGY
- PARP inhibition sensitizes endometrial cancer cells to paclitaxel-induced apoptosis
- (2017) Christine Dinkic et al. Oncology Letters
- Integrated Epigenomics Analysis Reveals a DNA Methylation Panel for Endometrial Cancer Detection Using Cervical Scrapings
- (2016) Rui-Lan Huang et al. CLINICAL CANCER RESEARCH
- Isoliquiritigenin induces apoptosis and autophagy and inhibits endometrial cancer growth in mice
- (2016) Chi-Hao Wu et al. Oncotarget
- Secalonic Acid-D Represses HIF1 /VEGF-Mediated Angiogenesis by Regulating the Akt/mTOR/p70S6K Signaling Cascade
- (2015) S. K. Guru et al. CANCER RESEARCH
- A Novel Microtubule-Disrupting Agent Induces Endoplasmic Reticular Stress-Mediated Cell Death in Human Hepatocellular Carcinoma Cells
- (2015) Chun-Te Ho et al. PLoS One
- Anti-tumor activity of olaparib, a poly (ADP-ribose) polymerase (PARP) inhibitor, in cultured endometrial carcinoma cells
- (2014) Aki Miyasaka et al. BMC CANCER
- Rational approaches, design strategies, structure activity relationship and mechanistic insights for anticancer hybrids
- (2014) Kunal Nepali et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- A dual tyrosine kinase inhibitor lapatinib suppresses overexpression of matrix metallopeptidase 1 (MMP1) in endometrial cancer
- (2014) Chiao-Yun Lin et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- Disruption of the PI3K/AKT/mTOR signaling cascade and induction of apoptosis in HL-60 cells by an essential oil from Monarda citriodora
- (2013) Anup Singh Pathania et al. FOOD AND CHEMICAL TOXICOLOGY
- Natural and glucosyl flavonoids inhibit poly(ADP-ribose) polymerase activity and induce synthetic lethality in BRCA mutant cells
- (2013) JUNKO MAEDA et al. ONCOLOGY REPORTS
- Benzyl isothiocyanate induces protective autophagy in human prostate cancer cells via inhibition of mTOR signaling
- (2012) Ji-Fan Lin et al. CARCINOGENESIS
- Anticancer activity, toxicity and pharmacokinetic profile of an indanone derivative
- (2012) Debabrata Chanda et al. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
- In-Silico ADME Models: A General Assessment of their Utility in Drug Discovery Applications
- (2011) M. Paul Gleeson et al. CURRENT TOPICS IN MEDICINAL CHEMISTRY
- Inhibition of AMPK-Associated Autophagy Enhances Caffeic Acid Phenethyl Ester-Induced Cell Death in C6 Glioma Cells
- (2011) Szu-Hsu Yu et al. PLANTA MEDICA
- Environmental causes of cancer: endocrine disruptors as carcinogens
- (2010) Ana M. Soto et al. Nature Reviews Endocrinology
- Frog2: Efficient 3D conformation ensemble generator for small compounds
- (2010) M. A. Miteva et al. NUCLEIC ACIDS RESEARCH
- Epigenetics in Cancer
- (2008) Manel Esteller NEW ENGLAND JOURNAL OF MEDICINE
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExplorePublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More