Genome-wide association and functional genomic analyses for various hoof health traits in North American Holstein cattle

Genome-wide host-pathogen analyses reveal genetic interaction points in tuberculosis disease

(2023) Jody Phelan et al.   Nature Communications

The bovine foot skin microbiota is associated with host genotype and the development of infectious digital dermatitis lesions

(2023) V. Bay et al.   Microbiome

Multi-omic analysis reveals divergent molecular events in scarring and regenerative wound healing

(2022) Shamik Mascharak et al.   Cell Stem Cell

Role of miRNAs in melanin metabolism: Implications in melanin‐related diseases

(2022) Zhigang Zhang et al.   Journal of Cosmetic Dermatology

Genome‐wide association studies in Japanese women identified genetic loci associated with wrinkles and sagging

(2022) Ryosuke Okuno et al.   EXPERIMENTAL DERMATOLOGY

Genomic inbreeding coefficients using imputed genotypes: Assessing different estimators in Holstein-Friesian dairy cows

(2022) Christos Dadousis et al.   JOURNAL OF DAIRY SCIENCE

Alberta dairy farmers’ and veterinarians’ opinion about bovine leukemia virus control measures

(2022) Alessa Kuczewski et al.   PREVENTIVE VETERINARY MEDICINE

Genomic analyses of claw disorders in Holstein cows: Genetic parameters, trait associations, and genome-wide associations considering interactions of SNP and heat stress

(2022) Niklas Sölzer et al.   JOURNAL OF DAIRY SCIENCE

Hoof lesions in partly housed pasture-based dairy cows

(2022) N. Browne et al.   JOURNAL OF DAIRY SCIENCE

Effect of concrete slats versus rubber-covered slats on the performance, behaviour, hoof health, cleanliness of finishing beef steers and performance, cleanliness and hoof health of weanling cattle

(2022) C.E. McGettigan et al.   Livestock Science

Prediction of potential molecular markers of bovine mastitis by meta-analysis of differentially expressed genes using combined p value and robust rank aggregation

(2022) Anushri Umesh et al.   TROPICAL ANIMAL HEALTH AND PRODUCTION

Continuous activation of the IL-17F driven inflammatory pathway in acute and chronic digital dermatitis lesions in dairy cattle

(2022) Anne-Sofie Vermeersch et al.   Scientific Reports

Genome-wide association studies for the identification of cattle susceptible and resilient to paratuberculosis

(2022) Marta Alonso-Hearn et al.   Frontiers in Veterinary Science

KLF9 positively regulates TRIM33 to inhibit abnormal synovial fibroblast proliferation, migration as well as inflammation in rheumatoid arthritis

(2022) Dan Huang et al.   Immunity Inflammation and Disease

Nomogram analysis of the influencing factors of diabetic foot in patients with diabetes mellitus

(2021) Mingming Li et al.   Hormones-International Journal of Endocrinology and Metabolism

The Ubiquitin Proteasome System and Skin Fibrosis

(2021) Wanlu Shen et al.   Molecular Diagnosis & Therapy

Epigenetic regulation of cellular functions in wound healing

(2021) Irena Pastar et al.   EXPERIMENTAL DERMATOLOGY

Genome-wide association study between copy number variants and hoof health traits in Holstein dairy cattle

(2021) Adrien M. Butty et al.   JOURNAL OF DAIRY SCIENCE

Estimated genetic parameters for all genetically evaluated traits in Canadian Holsteins

(2021) G.A. Oliveira Junior et al.   JOURNAL OF DAIRY SCIENCE

Genome-Wide Association Studies Reveal Susceptibility Loci for Noninfectious Claw Lesions in Holstein Dairy Cattle

(2021) Ellen Lai et al.   Frontiers in Genetics

Roles of the tissue-type plasminogen activator in immune response

(2021) Célia Seillier et al.   CELLULAR IMMUNOLOGY

A cross-population atlas of genetic associations for 220 human phenotypes

(2021) Saori Sakaue et al.   NATURE GENETICS

Pleiotropic Loci Associated With Foot Disorders and Common Periparturient Diseases in Holstein Cattle

(2021) Ellen Lai et al.   Frontiers in Genetics

Fibroblast Growth Factor in Diabetic Foot Ulcer: Progress and Therapeutic Prospects

(2021) Ye Liu et al.   Frontiers in Endocrinology

GWAS and fine-mapping of livability and six disease traits in Holstein cattle

(2020) Ellen Freebern et al.   BMC GENOMICS

Exploring physiological and genetic variation of digital cushion thickness in Holstein and Jersey cows and bulls

(2020) C.R. Stambuk et al.   JOURNAL OF DAIRY SCIENCE

Effect of genomic selection on rate of inbreeding and coancestry and effective population size of Holstein and Jersey cattle populations

(2020) Bayode O. Makanjuola et al.   JOURNAL OF DAIRY SCIENCE

GALLO: An R package for genomic annotation and integration of multiple data sources in livestock for positional candidate loci

(2020) Pablo A S Fonseca et al.   GigaScience

The importance of hoof health in dairy production

(2019) Lenka Krpálková et al.   Czech Journal of Animal Science

Genomic analysis of claw lesions in Holstein cows: Opportunities for genomic selection, quantitative trait locus detection, and gene identification

(2019) Iola Croué et al.   JOURNAL OF DAIRY SCIENCE

Claw disorders in dairy cattle: Effects on production, welfare and farm economics with possible prevention methods

(2019) Marie Alvergnas et al.   Livestock Science

Genome‐wide association study reveals candidate genes associated with body measurement traits in Chinese Wagyu beef cattle

(2019) B. An et al.   ANIMAL GENETICS

Osmolyte transporter expression is reduced in photoaged human skin: Implications for skin hydration in aging

(2019) April R. Foster et al.   AGING CELL

Antioxidants cinnamaldehyde and Galactomyces fermentation filtrate downregulate senescence marker CDKN2A/p16INK4A via NRF2 activation in keratinocytes

(2019) Akiko Hashimoto-Hachiya et al.   JOURNAL OF DERMATOLOGICAL SCIENCE

A resource-efficient tool for mixed model association analysis of large-scale data

(2019) Longda Jiang et al.   NATURE GENETICS

Fine mapping of genomic regions associated with female fertility in Nellore beef cattle based on sequence variants from segregating sires

(2019) Gerson A. Oliveira Júnior et al.   Journal of Animal Science and Biotechnology

Efficient analysis of large-scale genome-wide data with two R packages: bigstatsr and bigsnpr

(2018) Florian Privé et al.   BIOINFORMATICS

Invited review: Genetics and claw health: Opportunities to enhance claw health by genetic selection

(2018) B. Heringstad et al.   JOURNAL OF DAIRY SCIENCE

Short communication: Uncovering quantitative trait loci associated with resistance to Mycobacterium avium ssp. paratuberculosis infection in Holstein cattle using a high-density single nucleotide polymorphism panel

(2018) Sanjay Mallikarjunappa et al.   JOURNAL OF DAIRY SCIENCE

E3 ligase Trim21 ubiquitylates and stabilizes Keratin 17 to induce STAT3 activation in psoriasis

(2018) Luting Yang et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Integration of machine learning and meta-analysis identifies the transcriptomic bio-signature of mastitis disease in cattle

(2018) Somayeh Sharifi et al.   PLoS One

Prioritizing candidate genes post-GWAS using multiple sources of data for mastitis resistance in dairy cattle

(2018) Zexi Cai et al.   BMC GENOMICS

Building a livestock genetic and genomic information knowledgebase through integrative developments of Animal QTLdb and CorrDB

(2018) Zhi-Liang Hu et al.   NUCLEIC ACIDS RESEARCH

Genetic parameters for hoof health traits estimated with linear and threshold models using alternative cohorts

(2017) F. Malchiodi et al.   JOURNAL OF DAIRY SCIENCE

Effect of claw disorders on milk production, fertility, and longevity, and their economic impact in Spanish Holstein cows

(2017) N. Charfeddine et al.   JOURNAL OF DAIRY SCIENCE

Vitamin D receptor is a novel transcriptional regulator for Axin1

(2017) Dapeng Jin et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Novel SNPs in IL-17F and IL-17A genes associated with somatic cell count in Chinese Holstein and Inner-Mongolia Sanhe cattle

(2017) Tahir Usman et al.   Journal of Animal Science and Biotechnology

Unravelling the genomic architecture of bull fertility in Holstein cattle

(2016) Yi Han et al.   BMC GENETICS

Dnmt3a and Dnmt3b Associate with Enhancers to Regulate Human Epidermal Stem Cell Homeostasis

(2016) Lorenzo Rinaldi et al.   Cell Stem Cell

Interactions of the Immune System with Skin and Bone Tissue in Psoriatic Arthritis: A Comprehensive Review

(2016) Andrea Sukhov et al.   CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY

Short communication: Association of foot and leg conformation and body weight with claw disorders in Spanish Holstein cows

(2016) M.A. Pérez-Cabal et al.   JOURNAL OF DAIRY SCIENCE

Reference-based phasing using the Haplotype Reference Consortium panel

(2016) Po-Ru Loh et al.   NATURE GENETICS

Next-generation genotype imputation service and methods

(2016) Sayantan Das et al.   NATURE GENETICS

Analysis of Mineral Elements, Metabolism, and Inflammation Indexes in the Plasma of Dairy Cows Suffering from Different Degrees of Lameness

(2015) Dongbo Sun et al.   BIOLOGICAL TRACE ELEMENT RESEARCH

Interleukin-17A as a Biomarker for Bovine Tuberculosis

(2015) W. Ray Waters et al.   Clinical and Vaccine Immunology

Complement activation, regulation, and molecular basis for complement-related diseases

(2015) G. Bajic et al.   EMBO JOURNAL

Insights into peptidyl-prolyl cis–trans isomerase structure and function in immunocytes

(2015) Pulak Ranjan Nath et al.   IMMUNOLOGY LETTERS

Constitutive activation of STAT3 in breast cancer cells: A review

(2015) Kasturi Banerjee et al.   INTERNATIONAL JOURNAL OF CANCER

Joint genome-wide association study for milk fatty acid traits in Chinese and Danish Holstein populations

(2015) X. Li et al.   JOURNAL OF DAIRY SCIENCE

Genetic analysis of resistance to ticks, gastrointestinal nematodes and Eimeria spp. in Nellore cattle

(2015) Tiago Luciano Passafaro et al.   VETERINARY PARASITOLOGY

Laminins: Roles and Utility in Wound Repair

(2015) Valentina Iorio et al.   Advances in Wound Care

Relationships between Circulating Urea Concentrations and Endometrial Function in Postpartum Dairy Cows

(2015) Zhangrui Cheng et al.   Animals

Genetic effects of single nucleotide polymorphisms in JAK2 and STAT5A genes on susceptibility of Chinese Holsteins to mastitis

(2014) Tahir Usman et al.   MOLECULAR BIOLOGY REPORTS

The role of lipoxygenases in epidermis

(2013) Peter Krieg et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Concanavalin A-mediated T cell proliferation is regulated by herpes virus entry mediator costimulatory molecule

(2013) Yoshiaki Ando et al.   IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL

β-Catenin protects the epidermis from mechanical stresses

(2013) Samriddha Ray et al.   JOURNAL OF CELL BIOLOGY

Genetic parameters for hoof lesions and their relationship with feet and leg traits in Canadian Holstein cows

(2013) N. Chapinal et al.   JOURNAL OF DAIRY SCIENCE

Interdigital dermatitis, heel horn erosion, and digital dermatitis in 14 Norwegian dairy herds

(2013) M. Knappe-Poindecker et al.   JOURNAL OF DAIRY SCIENCE

Staphylokinase Promotes the Establishment of Staphylococcus aureus Skin Infections While Decreasing Disease Severity

(2013) Jakub Kwiecinski et al.   JOURNAL OF INFECTIOUS DISEASES

Relationships between bovine hoof disorders, body condition traits, and test-day yields

(2012) K. Schöpke et al.   JOURNAL OF DAIRY SCIENCE

Quantitative trait loci for clinical mastitis on chromosomes 2, 6, 14 and 20 in Norwegian Red cattle

(2011) M. Sodeland et al.   ANIMAL GENETICS

Accounting for multiple comparisons in a genome-wide association study (GWAS)

(2011) Randall C Johnson et al.   BMC GENOMICS

WWP1: a versatile ubiquitin E3 ligase in signaling and diseases

(2011) Xu Zhi et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Using the genomic relationship matrix to predict the accuracy of genomic selection

(2011) M.E. Goddard et al.   JOURNAL OF ANIMAL BREEDING AND GENETICS

Conditional deletion of Stat3 in mammary epithelium impairs the acute phase response and modulates immune cell numbers during post-lactational regression

(2011) Katherine Hughes et al.   JOURNAL OF PATHOLOGY

Exploring Staphylococcus aureus pathways to disease for vaccine development

(2011) Andrea DeDent et al.   Seminars in Immunopathology

GCTA: A Tool for Genome-wide Complex Trait Analysis

(2010) Jian Yang et al.   AMERICAN JOURNAL OF HUMAN GENETICS

A genome scan for quantitative trait loci influencing carcass, post-natal growth and reproductive traits in commercial Angus cattle

(2010) M. C. McClure et al.   ANIMAL GENETICS

Characteristics of linkage disequilibrium in North American Holsteins

(2010) Jarmila Bohmanova et al.   BMC GENOMICS

A whole genome association analysis identifies loci associated withMycobacterium aviumsubsp.paratuberculosisinfection status in US holstein cattle

(2009) M. Settles et al.   ANIMAL GENETICS

Alterations of the Cell-Cycle Inhibitors p27KIP1 and p16INK4a Are Frequent in Blastic Plasmacytoid Dendritic Cell Neoplasms

(2009) Thomas Wiesner et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

A systems perspective of host–pathogen interactions: predicting disease outcome in tuberculosis

(2009) Karthik Raman et al.   Molecular BioSystems

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

Fine-mapping QTL for mastitis resistance on BTA9 in three Nordic red cattle breeds

(2008) G. Sahana et al.   ANIMAL GENETICS

Roles of Pofut1 andO-Fucose in Mammalian Notch Signaling

(2008) Mark Stahl et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Complexity of complement activation in sepsis

(2008) Maciej M. Markiewski et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Detection of Quantitative Trait Loci in Danish Holstein Cattle Affecting Clinical Mastitis, Somatic Cell Score, Udder Conformation Traits, and Assessment of Associated Effects on Milk Yield

(2008) M.S. Lund et al.   JOURNAL OF DAIRY SCIENCE

Efficient Methods to Compute Genomic Predictions

(2008) P.M. VanRaden   JOURNAL OF DAIRY SCIENCE

Invited Review: Reliability of genomic predictions for North American Holstein bulls

(2008) P.M. VanRaden et al.   JOURNAL OF DAIRY SCIENCE