KLF9 positively regulates TRIM33 to inhibit abnormal synovial fibroblast proliferation, migration as well as inflammation in rheumatoid arthritis

Circular RNA circ_0130438 suppresses TNF-α-induced proliferation, migration, invasion and inflammation in human fibroblast-like MH7A synoviocytes by regulating miR-130a-3p/KLF9 axis

(2022) Lei Li et al.   TRANSPLANT IMMUNOLOGY

The crystallin alpha B (HSPB5)-tripartite motif containing 33 (TRIM33) axis mediates myocardial fibrosis induced by angiotensinogen II through transforming growth factor-β (TGF-β1)-Smad3/4 signaling

(2022) Tianwen Wei et al.   Bioengineered

The role of TRIM family proteins in autophagy, pyroptosis and diabetes mellitus

(2021) Tingting Wan et al.   CELL BIOLOGY INTERNATIONAL

Mechanism of miR-218-5p in autophagy, apoptosis and oxidative stress in rheumatoid arthritis synovial fibroblasts is mediated by KLF9 and JAK/STAT3 pathways

(2021) Ming Chen et al.   JOURNAL OF INVESTIGATIVE MEDICINE

Ub and Dub of RNF43/ZNRF3 in the WNT signalling pathway

(2021) Gabriele Colozza et al.   EMBO REPORTS

Fibroblast-like synoviocytes in rheumatoid arthritis: Surface markers and phenotypes

(2021) Zewen Wu et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

The translational values of TRIM family in pan-cancers: from functions and mechanisms to clinics

(2021) Guo Zhao et al.   PHARMACOLOGY & THERAPEUTICS

Ubiquitination, Biotech Startups, and the Future of TRIM Family Proteins: A TRIM-Endous Opportunity

(2021) Utsa Bhaduri et al.   Cells

TRIM33 protects osteoblasts from oxidative stress‐induced apoptosis in osteoporosis by inhibiting FOXO3a ubiquitylation and degradation

(2021) De‐bo Zou et al.   AGING CELL

TRIM33 prevents pulmonary fibrosis by impairing TGF-β1 signaling

(2020) Pierre-Marie Boutanquoi et al.   EUROPEAN RESPIRATORY JOURNAL

Secreted Protein Acidic and Rich in Cysteine Mediated Biomimetic Delivery of Methotrexate by Albumin-Based Nanomedicines for Rheumatoid Arthritis Therapy

(2019) Lu Liu et al.   ACS Nano

Up-regulation of TIF1γ by valproic acid inhibits the epithelial mesenchymal transition in prostate carcinoma through TGF-β/Smad signaling pathway

(2019) Guanghui Qi et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

TRIM33 is essential for osteoblast proliferation and differentiation via BMP pathway

(2017) Jia Guo et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Interleukin-1β affects the phospholipid biosynthesis of fibroblast-like synoviocytes from human osteoarthritic knee joints

(2017) K.D. Sluzalska et al.   OSTEOARTHRITIS AND CARTILAGE

TRIM Family Proteins: Roles in Autophagy, Immunity, and Carcinogenesis

(2017) Shigetsugu Hatakeyama   TRENDS IN BIOCHEMICAL SCIENCES

Krüppel-like factor 9 (KLF9) prevents colorectal cancer through inhibition of interferon-related signaling

(2015) Adam R. Brown et al.   CARCINOGENESIS

HIF-2α-induced chemokines stimulate motility of fibroblast-like synoviocytes and chondrocytes into the cartilage-pannus interface in experimental rheumatoid arthritis mouse models

(2015) Yun Hyun Huh et al.   ARTHRITIS RESEARCH & THERAPY

Interaction of Mesenchymal Stem Cells with Fibroblast-like Synoviocytes via Cadherin-11 Promotes Angiogenesis by Enhanced Secretion of Placental Growth Factor

(2014) S.-J. Park et al.   JOURNAL OF IMMUNOLOGY

Nrf2 Amplifies Oxidative Stress via Induction of Klf9

(2014) Shoshanna N. Zucker et al.   MOLECULAR CELL

Tripartite Motif-containing 33 (TRIM33) Protein Functions in the Poly(ADP-ribose) Polymerase (PARP)-dependent DNA Damage Response through Interaction with Amplified in Liver Cancer 1 (ALC1) Protein

(2013) Atul Kulkarni et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Pharmacological efficacy of anti-IL-1β scFv, Fab and full-length antibodies in treatment of rheumatoid arthritis

(2013) Jianying Qi et al.   MOLECULAR IMMUNOLOGY

Duality of fibroblast-like synoviocytes in RA: passive responders and imprinted aggressors

(2012) Nunzio Bottini et al.   Nature Reviews Rheumatology

Differential effects of Th1 versus Th2 cytokines in combination with hypoxia on HIFs and angiogenesis in RA

(2012) Helene Larsen et al.   ARTHRITIS RESEARCH & THERAPY

Transcription cofactors TRIM24, TRIM28, and TRIM33 associate to form regulatory complexes that suppress murine hepatocellular carcinoma

(2011) B. Herquel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The role and therapeutic implications of fibroblast-like synoviocytes in inflammation and cartilage erosion in rheumatoid arthritis

(2008) Erika H. Noss et al.   IMMUNOLOGICAL REVIEWS