Multi-omic analysis reveals divergent molecular events in scarring and regenerative wound healing

Inference and analysis of cell-cell communication using CellChat

(2021) Suoqin Jin et al.   Nature Communications

Preventing Engrailed-1 activation in fibroblasts yields wound regeneration without scarring

(2021) Shamik Mascharak et al.   SCIENCE

Integrated spatial multiomics reveals fibroblast fate during tissue repair

(2021) Deshka S. Foster et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Multi-level transcriptome sequencing identifies COL1A1 as a candidate marker in human heart failure progression

(2020) Xiumeng Hua et al.   BMC Medicine

Single-cell transcriptional diversity is a hallmark of developmental potential

(2020) Gunsagar S. Gulati et al.   SCIENCE

Distinct Regulatory Programs Control the Latent Regenerative Potential of Dermal Fibroblasts during Wound Healing

(2020) Sepideh Abbasi et al.   Cell Stem Cell

Understanding the impact of fibroblast heterogeneity on skin fibrosis

(2020) Michelle F. Griffin et al.   Disease Models & Mechanisms

Targeting focal adhesion kinase in cancer cells and the tumor microenvironment

(2020) James M. Murphy et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

Generalizing RNA velocity to transient cell states through dynamical modeling

(2020) Volker Bergen et al.   NATURE BIOTECHNOLOGY

A scalable SCENIC workflow for single-cell gene regulatory network analysis

(2020) Bram Van de Sande et al.   Nature Protocols

Fibroblast Heterogeneity in Wound Healing: Hurdles to Clinical Translation

(2020) Shamik Mascharak et al.   TRENDS IN MOLECULAR MEDICINE

Single‐cell transcriptomic analysis of small and large wounds reveals the distinct spatial organization of regenerative fibroblasts

(2020) Quan M. Phan et al.   EXPERIMENTAL DERMATOLOGY

Mechanical Forces in Cutaneous Wound Healing: Emerging Therapies to Minimize Scar Formation

(2018) Leandra A. Barnes et al.   Advances in Wound Care

TRPS1 shapes YAP/TEAD-dependent transcription in breast cancer cells

(2018) Dana Elster et al.   Nature Communications

EzColocalization: An ImageJ plugin for visualizing and measuring colocalization in cells and organisms

(2018) Weston Stauffer et al.   Scientific Reports

Hedgehog stimulates hair follicle neogenesis by creating inductive dermis during murine skin wound healing

(2018) Chae Ho Lim et al.   Nature Communications

Regional Control of Hairless versus Hair-Bearing Skin by Dkk2

(2018) Yaolin Song et al.   Cell Reports

Attenuation of pulmonary fibrosis in type I collagen-targeted reporter mice with ALK-5 inhibitors

(2018) Hideki Terashima et al.   PULMONARY PHARMACOLOGY & THERAPEUTICS

SCENIC: single-cell regulatory network inference and clustering

(2017) Sara Aibar et al.   NATURE METHODS

Targeting of cadherin-11 decreases skin fibrosis in the tight skin-1 mouse model

(2017) Mesias Pedroza et al.   PLoS One

A Tissue-Mapped Axolotl De Novo Transcriptome Enables Identification of Limb Regeneration Factors

(2017) Donald M. Bryant et al.   Cell Reports

Identification and isolation of a dermal lineage with intrinsic fibrogenic potential

(2015) Y. Rinkevich et al.   SCIENCE

The dynamics and regulators of cell fate decisions are revealed by pseudotemporal ordering of single cells

(2014) Cole Trapnell et al.   NATURE BIOTECHNOLOGY

Enrichr: interactive and collaborative HTML5 gene list enrichment analysis tool

(2013) Edward Y Chen et al.   BMC BIOINFORMATICS

Epithelial Wnt Ligand Secretion Is Required for Adult Hair Follicle Growth and Regeneration

(2012) Peggy S. Myung et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Trps1 and Its Target Gene Sox9 Regulate Epithelial Proliferation in the Developing Hair Follicle and Are Associated with Hypertrichosis

(2012) Katherine A. Fantauzzo et al.   PLoS Genetics

Trps1 activates a network of secreted Wnt inhibitors and transcription factors crucial to vibrissa follicle morphogenesis

(2011) K. A. Fantauzzo et al.   DEVELOPMENT

Cadherin-11 contributes to pulmonary fibrosis: potential role in TGF-β production and epithelial to mesenchymal transition

(2011) Daniel J. Schneider et al.   FASEB JOURNAL

Focal adhesion kinase links mechanical force to skin fibrosis via inflammatory signaling

(2011) Victor W Wong et al.   NATURE MEDICINE

A position effect on TRPS1 is associated with Ambras syndrome in humans and the Koala phenotype in mice

(2008) K. A. Fantauzzo et al.   HUMAN MOLECULAR GENETICS

Scar Treatments: Preclinical and Clinical Studies

(2008) Richard G. Reish et al.   JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS

Dynamic expression of the zinc-finger transcription factor Trps1 during hair follicle morphogenesis and cycling

(2007) Katherine A. Fantauzzo et al.   GENE EXPRESSION PATTERNS