HIV-1 subtypes maintain distinctive physicochemical signatures in Nef domains associated with immunoregulation

Antiretroviral Drugs for Treatment and Prevention of HIV Infection in Adults

(2022) Rajesh T. Gandhi et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

The Persistence of HIV Diversity, Transcription, and Nef Protein in Kaposi’s Sarcoma Tumors during Antiretroviral Therapy

(2022) David J. Nolan et al.   Viruses-Basel

The Interplay of HIV-1 and Macrophages in Viral Persistence

(2021) Chynna M. Hendricks et al.   Frontiers in Microbiology

HIV-1 Nef interacts with the cyclin K/CDK13 complex to antagonize SERINC5 for optimal viral infectivity

(2021) Qingqing Chai et al.   Cell Reports

HIV-1 subtype distribution and diversity over 18 years in Rakai, Uganda

(2020) Susanna Lamers et al.   AIDS RESEARCH AND HUMAN RETROVIRUSES

The Biology of the HIV-1 Latent Reservoir and Implications for Cure Strategies

(2020) Lillian B. Cohn et al.   Cell Host & Microbe

Structural basis of CD4 downregulation by HIV-1 Nef

(2020) Yonghwa Kwon et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Nef Homodimers Downregulate SERINC5 by AP-2-Mediated Endocytosis to Promote HIV-1 Infectivity

(2020) Ryan P. Staudt et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Concanamycin A counteracts HIV-1 Nef to enhance immune clearance of infected primary cells by cytotoxic T lymphocytes

(2020) Mark M. Painter et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Variation in HIV-1 Nef function within and among viral subtypes reveals genetically separable antagonism of SERINC3 and SERINC5

(2020) Steven W. Jin et al.   PLoS Pathogens

Carboxymethyl dextran‐trimethyl chitosan coated superparamagnetic iron oxide nanoparticles: An effective siRNA delivery system for HIV‐1 Nef

(2019) Sara Kamalzare et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Nef-mediated inhibition of NFAT following TCR stimulation differs between HIV-1 subtypes

(2019) Lisa Naidoo et al.   VIROLOGY

Exosomes containing HIV protein Nef reorganize lipid rafts potentiating inflammatory response in bystander cells

(2019) Nigora Mukhamedova et al.   PLoS Pathogens

How HIV Nef Proteins Hijack Membrane Traffic To Promote Infection

(2019) Cosmo Z. Buffalo et al.   JOURNAL OF VIROLOGY

Viral protein Nef is detected in plasma of half of HIV-infected adults with undetectable plasma HIV RNA

(2018) Jana Ferdin et al.   PLoS One

Nef Secretion into Extracellular Vesicles or Exosomes Is Conserved across Human and Simian Immunodeficiency Viruses

(2018) Ryan P. McNamara et al.   mBio

Tissue issues

(2018) Barbara L. Shacklett et al.   Current Opinion in HIV and AIDS

Predicted coreceptor usage at end-stage HIV disease in tissues derived from subjects on antiretroviral therapy with an undetectable plasma viral load

(2017) S.L. Lamers et al.   INFECTION GENETICS AND EVOLUTION

Evolving epidemiology of HIV-associated malignancies

(2017) Meredith S. Shiels et al.   Current Opinion in HIV and AIDS

HIV-1 Nef Signaling in Intestinal Mucosa Epithelium Suggests the Existence of an Active Inter-kingdom Crosstalk Mediated by Exosomes

(2017) Cristina Felli et al.   Frontiers in Microbiology

On the Physicochemical and Structural Modifications Associated with HIV-1 Subtype B Tropism Transition

(2016) Susanna L. Lamers et al.   AIDS RESEARCH AND HUMAN RETROVIRUSES

Persistent, Albeit Reduced, Chronic Inflammation in Persons Starting Antiretroviral Therapy in Acute HIV Infection

(2016) Irini Sereti et al.   CLINICAL INFECTIOUS DISEASES

HIV Maintains an Evolving and Dispersed Population in Multiple Tissues during Suppressive Combined Antiretroviral Therapy in Individuals with Cancer

(2016) Rebecca Rose et al.   JOURNAL OF VIROLOGY

HIV-1 Nef: Taking Control of Protein Trafficking

(2016) Estela A. Pereira et al.   TRAFFIC

A Highly Conserved Residue in HIV-1 Nef Alpha Helix 2 Modulates Protein Expression

(2016) Aaron L. Johnson et al.   mSphere

Identification of dual-tropic HIV-1 using evolved neural networks

(2015) Gary B. Fogel et al.   BIOSYSTEMS

The Contribution of Extracellular Nef to HIV-Induced Pathogenesis

(2015) Eleonora Olivetta et al.   CURRENT DRUG TARGETS

Tracking the Emergence of Host-Specific Simian Immunodeficiency VirusenvandnefPopulations RevealsnefEarly Adaptation and Convergent Evolution in Brain of Naturally Progressing Rhesus Macaques

(2015) Susanna L. Lamers et al.   JOURNAL OF VIROLOGY

HIV-1 Nef hijacks clathrin coats by stabilizing AP-1:Arf1 polygons

(2015) Q.-T. Shen et al.   SCIENCE

COMET: adaptive context-based modeling for ultrafast HIV-1 subtype identification

(2014) Daniel Struck et al.   NUCLEIC ACIDS RESEARCH

How HIV-1 Nef hijacks the AP-2 clathrin adaptor to downregulate CD4

(2014) Xuefeng Ren et al.   eLife

Disease progression by infecting HIV-1 subtype in a seroconverter cohort in sub-Saharan Africa

(2013) Pauli N. Amornkul et al.   AIDS

Synergy between Kaposi's sarcoma-associated herpesvirus (KSHV) vIL-6 and HIV-1 Nef protein in promotion of angiogenesis and oncogenesis: role of the AKT signaling pathway

(2013) X Zhu et al.   ONCOGENE

Ability of HIV-1 Nef to downregulate CD4 and HLA class I differs among viral subtypes

(2013) Jaclyn K Mann et al.   Retrovirology

HIV reservoirs

(2012) Tae-Wook Chun et al.   AIDS

HIV-1 Nef in Macrophage-Mediated Disease Pathogenesis

(2012) Susanna L. Lamers et al.   INTERNATIONAL REVIEWS OF IMMUNOLOGY

Inhibition of the Nef regulatory protein of HIV-1 by a single-domain antibody

(2011) J. Bouchet et al.   BLOOD

Changes in the Distribution of HIV Type 1 Subtypes D and A in Rakai District, Uganda Between 1994 and 2002

(2010) Samantha A. Conroy et al.   AIDS RESEARCH AND HUMAN RETROVIRUSES

Geographic HIV Type 1 Subtype Distribution in Rakai District, Uganda

(2009) Aleisha N. Collinson-Streng et al.   AIDS RESEARCH AND HUMAN RETROVIRUSES

Prediction of R5, X4, and R5X4 HIV-1 Coreceptor Usage with Evolved Neural Networks

(2008) S.L. Lamers et al.   IEEE-ACM Transactions on Computational Biology and Bioinformatics