Overexpression of GPX4 attenuates cognitive dysfunction through inhibiting hippocampus ferroptosis and neuroinflammation after traumatic brain injury

Ferrostatin-1 Polarizes Microglial Cells Toward M2 Phenotype to Alleviate Inflammation After Intracerebral Hemorrhage

(2022) Lijuan Huang et al.   Neurocritical Care

GPX4 degradation via chaperone-mediated autophagy contributes to antimony-triggered neuronal ferroptosis

(2022) Shali Yu et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Irisin protects against sepsis-associated encephalopathy by suppressing ferroptosis via activation of the Nrf2/GPX4 signal axis

(2022) Jin Wang et al.   FREE RADICAL BIOLOGY AND MEDICINE

ACSL4 deficiency confers protection against ferroptosis-mediated acute kidney injury

(2022) Yue Wang et al.   Redox Biology

Ferroptosis turns 10: Emerging mechanisms, physiological functions, and therapeutic applications

(2022) Brent R. Stockwell   CELL

PPARα alleviates iron overload‐induced ferroptosis in mouse liver

(2022) Guowei Xing et al.   EMBO REPORTS

Peroxisome proliferator-activated receptor-γ ameliorates neuronal ferroptosis after traumatic brain injury in mice by inhibiting cyclooxygenase-2

(2022) Hui Liang et al.   EXPERIMENTAL NEUROLOGY

Conditional knockout of ASK1 in microglia/macrophages attenuates epileptic seizures and long-term neurobehavioural comorbidities by modulating the inflammatory responses of microglia/macrophages

(2022) Yiying Zhang et al.   Journal of Neuroinflammation

STAT6 inhibits ferroptosis and alleviates acute lung injury via regulating P53/SLC7A11 pathway

(2022) Youjing Yang et al.   Cell Death & Disease

Ferroptosis in brain microvascular endothelial cells mediates blood-brain barrier disruption after traumatic brain injury

(2022) Jiang Fang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Lipid Peroxides Mediated Ferroptosis in Electromagnetic Pulse-Induced Hippocampal Neuronal Damage via Inhibition of GSH/GPX4 Axis

(2022) Yunfei Lai et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Netrin‐1 upregulates GPX4 and prevents ferroptosis after traumatic brain injury via the UNC5B/Nrf2 signaling pathway

(2022) Yuanda Zhang et al.   CNS Neuroscience & Therapeutics

TrkB agonist N-acetyl serotonin promotes functional recovery after traumatic brain injury by suppressing ferroptosis via the PI3K/Akt/Nrf2/Ferritin H pathway

(2022) Ying Cheng et al.   FREE RADICAL BIOLOGY AND MEDICINE

Ferroptosis: mechanisms, biology and role in disease

(2021) Xuejun Jiang et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Selective Ferroptosis Inhibitor Liproxstatin-1 Attenuates Neurological Deficits and Neuroinflammation After Subarachnoid Hemorrhage

(2021) Yang Cao et al.   Neuroscience Bulletin

Direct Mapping of Phospholipid Ferroptotic Death Signals in Cells and Tissues by Gas Cluster Ion Beam Secondary Ion Mass Spec‐trometry (GCIB‐SIMS)

(2021) Louis Sparvero et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Pharmacological blockers of CCR5 and CXCR4 improve recovery after traumatic brain injury

(2021) Yael Friedman-Levi et al.   EXPERIMENTAL NEUROLOGY

Ruxolitinib exerts neuroprotection via repressing ferroptosis in a mouse model of traumatic brain injury

(2021) Xueshi Chen et al.   EXPERIMENTAL NEUROLOGY

Prokineticin-2 prevents neuronal cell deaths in a model of traumatic brain injury

(2021) Zhongyuan Bao et al.   Nature Communications

The Potential Value of Targeting Ferroptosis in Early Brain Injury After Acute CNS Disease

(2020) Junhui Chen et al.   Frontiers in Molecular Neuroscience

Phosphoinositide Profile of the Mouse Retina

(2020) Stella Finkelstein et al.   Cells

Quercetin alleviates acute kidney injury by inhibiting ferroptosis

(2020) Yue Wang et al.   Journal of Advanced Research

Neuroprotective role of glutathione peroxidase 4 in experimental subarachnoid hemorrhage models

(2020) Sheng-Qing Gao et al.   LIFE SCIENCES

Deletion of ferritin H in neurons counteracts the protective effect of melatonin against traumatic brain injury‐induced ferroptosis

(2020) Tongyu Rui et al.   JOURNAL OF PINEAL RESEARCH

Lysophospholipid Acyltransferases and Leukotriene Biosynthesis: Intersection of the Lands Cycle and the Arachidonate PI cycle

(2019) Robert C. Murphy et al.   JOURNAL OF LIPID RESEARCH

Traumatic brain injury: global collaboration for a global challenge

(2019) Angelos G Kolias et al.   LANCET NEUROLOGY

Traumatic brain injury in China

(2019) Ji-Yao Jiang et al.   LANCET NEUROLOGY

A Role for Postsynaptic Density 95 and its Binding Partners in Models of Traumatic Brain Injury

(2019) Mihir V. Patel et al.   JOURNAL OF NEUROTRAUMA

Selenium Drives a Transcriptional Adaptive Program to Block Ferroptosis and Treat Stroke

(2019) Ishraq Alim et al.   CELL

2-Arachidonoylglycerol: A signaling lipid with manifold actions in the brain

(2018) Marc P. Baggelaar et al.   PROGRESS IN LIPID RESEARCH

Glutathione peroxidase 4 participates in secondary brain injury through mediating ferroptosis in a rat model of intracerebral hemorrhage

(2018) Zhuwei Zhang et al.   BRAIN RESEARCH

Inhibition of ferroptosis attenuates tissue damage and improves long-term outcomes after traumatic brain injury in mice

(2018) Bao-Shu Xie et al.   CNS Neuroscience & Therapeutics

Ferroptosis Contributes to Neuronal Death and Functional Outcome After Traumatic Brain Injury

(2018) Elizabeth M. Kenny et al.   CRITICAL CARE MEDICINE

Activation of Glutathione Peroxidase 4 as a Novel Anti-inflammatory Strategy

(2018) Cong Li et al.   Frontiers in Pharmacology

Oxidative Stress, Synaptic Dysfunction, and Alzheimer’s Disease

(2017) Eric Tönnies et al.   JOURNAL OF ALZHEIMERS DISEASE

The far-reaching scope of neuroinflammation after traumatic brain injury

(2017) Dennis W. Simon et al.   Nature Reviews Neurology

Ablation of ferroptosis regulator glutathione peroxidase 4 in forebrain neurons promotes cognitive impairment and neurodegeneration

(2017) William Sealy Hambright et al.   Redox Biology

Pathophysiology of Traumatic Brain Injury

(2016) Melissa J. McGinn et al.   NEUROSURGERY CLINICS OF NORTH AMERICA

Inflammatory reaction after traumatic brain injury: therapeutic potential of targeting cell–cell communication by chemokines

(2015) Stefka Gyoneva et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Polyunsaturated fatty acids and their metabolites in brain function and disease

(2014) Richard P. Bazinet et al.   NATURE REVIEWS NEUROSCIENCE

Phosphatidylserine in the brain: Metabolism and function

(2014) Hee-Yong Kim et al.   PROGRESS IN LIPID RESEARCH

Chemokine CCL2 Induces Apoptosis in Cortex Following Traumatic Brain Injury

(2013) Su Liu et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Changing patterns in the epidemiology of traumatic brain injury

(2013) Bob Roozenbeek et al.   Nature Reviews Neurology

Analysis of Transduction Efficiency, Tropism and Axonal Transport of AAV Serotypes 1, 2, 5, 6, 8 and 9 in the Mouse Brain

(2013) Dominik F. Aschauer et al.   PLoS One

Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death

(2012) Scott J. Dixon et al.   CELL

Role of CCL2 (MCP-1) in Traumatic Brain Injury (TBI): Evidence from Severe TBI Patients and CCL2−/− Mice

(2010) Bridgette D Semple et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM