Irisin protects against sepsis-associated encephalopathy by suppressing ferroptosis via activation of the Nrf2/GPX4 signal axis

Astaxanthin improves the development of the follicles and oocytes through alleviating oxidative stress induced by BPA in cultured follicles

(2022) Yaqiu Li et al.   Scientific Reports

ACSL4 exacerbates ischemic stroke by promoting ferroptosis-induced brain injury and neuroinflammation

(2021) Yu Cui et al.   BRAIN BEHAVIOR AND IMMUNITY

Legumain promotes tubular ferroptosis by facilitating chaperone-mediated autophagy of GPX4 in AKI

(2021) Chuan’ai Chen et al.   Cell Death & Disease

The Time-Course of Antioxidant Irisin Activity: Role of the Nrf2/HO-1/HMGB1 Axis

(2021) Agnieszka Irena Mazur-Bialy et al.   Antioxidants

Hydrogen sulfide attenuates ferroptosis and stimulates autophagy by blocking mTOR signaling in sepsis-induced acute lung injury

(2021) Jianhua Li et al.   MOLECULAR IMMUNOLOGY

Irisin Rescues Blood-Brain Barrier Permeability following Traumatic Brain Injury and Contributes to the Neuroprotection of Exercise in Traumatic Brain Injury

(2021) Peipei Guo et al.   Oxidative Medicine and Cellular Longevity

Combination of melatonin and irisin ameliorates lipopolysaccharide‐induced cardiac dysfunction through suppressing the Mst1–JNK pathways

(2020) Haichun Ouyang et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Proteomic analysis reveals that calcium channel blockers affect radicle protrusion during rice seed germination

(2020) Ming Li et al.   PLANT GROWTH REGULATION

Ferroptosis: past, present and future

(2020) Jie Li et al.   Cell Death & Disease

Inhibition of Ferroptosis Alleviates Early Brain Injury After Subarachnoid Hemorrhage In Vitro and In Vivo via Reduction of Lipid Peroxidation

(2020) Yuchen Li et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Sepsis-associated encephalopathy and septic encephalitis: an update

(2020) Simone C. Tauber et al.   Expert Review of Anti-Infective Therapy

Sepsis and Cerebral Dysfunction: BBB Damage, Neuroinflammation, Oxidative Stress, Apoptosis and Autophagy as Key Mediators and the Potential Therapeutic Approaches

(2020) Ming Gu et al.   NEUROTOXICITY RESEARCH

Nrf2 and STAT3 Alleviates Ferroptosis-Mediated IIR-ALI by Regulating SLC7A11

(2020) Zhuanzhuan Qiang et al.   Oxidative Medicine and Cellular Longevity

Serum irisin levels are decreased in patients with sepsis, and exogenous irisin suppresses ferroptosis in the liver of septic mice

(2020) Shasha Wei et al.   Clinical and Translational Medicine

The Neuroprotective Effect of Irisin in Ischemic Stroke

(2020) Yaqiang Liu et al.   Frontiers in Aging Neuroscience

NRF2 plays a critical role in mitigating lipid peroxidation and ferroptosis

(2019) Matthew Dodson et al.   Redox Biology

A role for FNDC5/Irisin in the beneficial effects of exercise on the brain and in neurodegenerative diseases

(2019) Michael F. Young et al.   PROGRESS IN CARDIOVASCULAR DISEASES

Ferroptosis and Brain Injury

(2019) Leslie Magtanong et al.   DEVELOPMENTAL NEUROSCIENCE

The S1P mimetic fingolimod phosphate regulates mitochondrial oxidative stress in neuronal cells

(2019) E. Martín-Montañez et al.   FREE RADICAL BIOLOGY AND MEDICINE

Ferroptosis is governed by differential regulation of transcription in liver cancer

(2019) Xiao Zhang et al.   Redox Biology

Mitochondria regulation in ferroptosis

(2019) Hai Wang et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Inhibition of ferroptosis attenuates tissue damage and improves long-term outcomes after traumatic brain injury in mice

(2018) Bao-Shu Xie et al.   CNS Neuroscience & Therapeutics

Ferroptosis Contributes to Neuronal Death and Functional Outcome After Traumatic Brain Injury

(2018) Elizabeth M. Kenny et al.   CRITICAL CARE MEDICINE

A polymorphism in the Irisin-encoding gene (FNDC5) associates with hepatic steatosis by differential miRNA binding to the 3′UTR

(2018) Mayada Metwally et al.   JOURNAL OF HEPATOLOGY

Exercise-linked FNDC5/irisin rescues synaptic plasticity and memory defects in Alzheimer’s models

(2018) Mychael V. Lourenco et al.   NATURE MEDICINE

The novel exercise-induced hormone irisin protects against neuronal injury via activation of the Akt and ERK1/2 signaling pathways and contributes to the neuroprotection of physical exercise in cerebral ischemia

(2017) Dong-Jie Li et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Brain Oxidative Stress During Experimental Sepsis Is Attenuated by Simvastatin Administration

(2016) Carlos Henrique Rocha Catalão et al.   MOLECULAR NEUROBIOLOGY

Ferroptosis, a newly characterized form of cell death in Parkinson's disease that is regulated by PKC

(2016) Bruce Do Van et al.   NEUROBIOLOGY OF DISEASE

Ferroptosis as a p53-mediated activity during tumour suppression

(2015) Le Jiang et al.   NATURE

Irisin and FGF21 Are Cold-Induced Endocrine Activators of Brown Fat Function in Humans

(2014) Paul Lee et al.   Cell Metabolism

The role of Nox2-derived ROS in the development of cognitive impairment after sepsis

(2014) Marina S Hernandes et al.   Journal of Neuroinflammation

Mitochondria-Targeted Peptide Reverses Mitochondrial Dysfunction and Cognitive Deficits in Sepsis-Associated Encephalopathy

(2014) Jing Wu et al.   MOLECULAR NEUROBIOLOGY

Irisin is inversely associated with intrahepatic triglyceride contents in obese adults

(2013) Hui-Jie Zhang et al.   JOURNAL OF HEPATOLOGY

A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis

(2012) Pontus Boström et al.   NATURE

Morphofunctional Aspects of the Blood-Brain Barrier

(2011) Beatrice Nico et al.   CURRENT DRUG METABOLISM

Neuro-oxidative-nitrosative stress in sepsis

(2011) Ronan MG Berg et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Septic encephalopathy: Inflammation in man and mouse

(2011) Alexander Jacob et al.   NEUROCHEMISTRY INTERNATIONAL

Long-term Cognitive Impairment and Functional Disability Among Survivors of Severe Sepsis

(2010) Theodore J. Iwashyna et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION