Cadmium exposure caused cardiotoxicity in common carps (Cyprinus carpio L.): miR-9-5p, oxidative stress, energetic impairment, mitochondrial division/fusion imbalance, inflammation, and autophagy

The effect of acute toxicity from tributyltin on Liza haematocheila liver: Energy metabolic disturbance, oxidative stress, and apoptosis

(2023) Changsheng Zhao et al.   AQUATIC TOXICOLOGY

Chlorpyrifos induced autophagy and mitophagy in common carp livers through AMPK pathway activated by energy metabolism disorder

(2023) Jiawen Cui et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Perfluorooctane sulfonate‐induced apoptosis in kidney cells by triggering the NOX4/ROS/JNK axis and antagonism of cannabidiol

(2023) Yongzhen Du et al.   ENVIRONMENTAL TOXICOLOGY

EGCG alleviated Mn exposure-caused carp kidney damage via trpm2-NLRP3-TNF-α-JNK pathway: Oxidative stress, inflammation, and tight junction dysfunction

(2023) Qin Zhou et al.   FISH & SHELLFISH IMMUNOLOGY

Nano-selenium protects grass carp hepatocytes against 4-tert-butylphenol-induced mitochondrial apoptosis and necroptosis via suppressing ROS-PARP1 axis

(2023) Jiawen Cui et al.   FISH & SHELLFISH IMMUNOLOGY

Cannabidiol Alleviates Perfluorooctanesulfonic Acid-Induced Cardiomyocyte Apoptosis by Maintaining Mitochondrial Dynamic Balance and Energy Metabolic Homeostasis

(2023) Xixi Wang et al.   Journal of Agricultural and Food Chemistry

Transcriptome analysis revealed the mechanism of Luciobarbus capito (L. capito) adapting high salinity: Antioxidant capacity, heat shock proteins, immunity

(2023) Xinchi Shang et al.   Marine Pollution Bulletin

Anadromous fish as biomarkers for the combined impact of marine and freshwater heavy metal pollution

(2022) M. Foley et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Selenium protects against cadmium‐induced cardiac injury by attenuating programmed cell death via PI3K / AKT / PTEN signaling

(2022) Jiapei Feng et al.   ENVIRONMENTAL TOXICOLOGY

Myocardin/microRNA-30a/Beclin1 signaling controls the phenotypic modulation of vascular smooth muscle cells by regulating autophagy

(2022) Danyang Shi et al.   Cell Death & Disease

Polysaccharide from dandelion enriched nutritional composition, antioxidant capacity, and inhibited bioaccumulation and inflammation in Channa asiatica under hexavalent chromium exposure

(2022) Lei Zhao et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Pollution and risk assessment of heavy metals in water, sediment and fish (Clarias gariepinus) in a fish farm cluster in Niger Delta region, Nigeria

(2022) Victor Chibuikem Ehiemere et al.   JOURNAL OF WATER AND HEALTH

Genetic Ablation of Na,K-ATPase α4 Results in Sperm Energetic Defects

(2022) September Numata et al.   Frontiers in Cell and Developmental Biology

Role of miR-451 in mediating cadmium induced head kidney injury in common carp via targeting cacna1ab through autophagy pathways

(2022) Peixian Luan et al.   AQUATIC TOXICOLOGY

Urinary metals as influencing factors of coronary heart disease among a population in Guangzhou, China

(2022) Xiang Liu et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

AMPK Activation Alleviates Myocardial Ischemia-Reperfusion Injury by Regulating Drp1-Mediated Mitochondrial Dynamics

(2022) Jingxia Du et al.   Frontiers in Pharmacology

Atrazine exposure induces necroptosis through the P450/ROS pathway and causes inflammation in the gill of common carp (Cyprinus carpio L.)

(2022) Tong Xu et al.   FISH & SHELLFISH IMMUNOLOGY

Polystyrene microplastics-induced cardiotoxicity in chickens via the ROS-driven NF-κB-NLRP3-GSDMD and AMPK-PGC-1α axes

(2022) Yue Zhang et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Melatonin alleviates lead-induced fatty liver in the common carps (Cyprinus carpio) via gut-liver axis

(2022) Zhiying Miao et al.   ENVIRONMENTAL POLLUTION

Melatonin alleviates lead-induced intestinal epithelial cell pyroptosis in the common carps (Cyprinus carpio) via miR-17-5p/TXNIP axis

(2022) Zhiying Miao et al.   FISH & SHELLFISH IMMUNOLOGY

Evaluation of Taraxacum mongolicum flavonoids in diets for Channa argus based on growth performance, immune responses, apoptosis and antioxidant defense system under lipopolysaccharide stress

(2022) Jia-Hua Du et al.   FISH & SHELLFISH IMMUNOLOGY

Platycodon grandiflorus Polysaccharides Alleviate Cr(VI)-Induced Apoptosis in DF-1 Cells via ROS-Drp1 Signal Pathway

(2022) Zhuanglong Zhang et al.   Life-Basel

Combined negative effects of microplastics and plasticizer DEHP: The increased release of Nets delays wound healing in mice

(2022) Xu Shi et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Transcriptome sequencing reveals genes involved in cadmium-triggered oxidative stress in the chicken heart

(2021) Chunlin Yu et al.   POULTRY SCIENCE

Inflammatory Injury and Mitophagy in the Cock Heart Induced by the Oral Administration of Hexavalent Chromium

(2021) Yue Wang et al.   BIOLOGICAL TRACE ELEMENT RESEARCH

Th1/Th2 imbalance and heat shock protein mediated inflammatory damage triggered by manganese via activating NF-κB pathway in chicken nervous system in vivo and in vitro

(2021) Zhiying Miao et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

NLRP3 inflammasome mediated pyroptosis is involved in cadmium exposure-induced neuroinflammation through the IL-1β/IkB-α-NF-κB-NLRP3 feedback loop in swine

(2021) Jingzeng Cai et al.   TOXICOLOGY

Comparison of nanoparticle-selenium, selenium-enriched yeast and sodium selenite on the alleviation of cadmium-induced inflammation via NF-kB/IκB pathway in heart

(2021) Jing Ge et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Dietary Taraxacum mongolicum polysaccharide ameliorates the growth, immune response, and antioxidant status in association with NF-κB, Nrf2 and TOR in Jian carp (Cyprinus carpio var. Jian)

(2021) Zhe Yu et al.   AQUACULTURE

Bacillus coagulans SCC-19 maintains intestinal health in cadmium-exposed common carp (Cyprinus carpio L.) by strengthening the gut barriers, relieving oxidative stress and modulating the intestinal microflora

(2021) Xulu Chang et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

The contributions of miR-25-3p, oxidative stress, and heat shock protein in a complex mechanism of autophagy caused by pollutant cadmium in common carp (Cyprinus carpio L.) hepatopancreas

(2021) Zhuo Li et al.   ENVIRONMENTAL POLLUTION

Urinary Cadmium and Incident Heart Failure

(2021) Clara G. Sears et al.   EPIDEMIOLOGY

Induction of autophagy via the ROS-dependent AMPK-mTOR pathway protects copper-induced spermatogenesis disorder

(2021) Hongrui Guo et al.   Redox Biology

Mfn2 Ablation in the Adult Mouse Hippocampus and Cortex Causes Neuronal Death

(2020) Song Han et al.   Cells

Whole transcriptome-based miRNA-mRNA network analysis revealed the mechanism of inflammation-immunosuppressive damage caused by cadmium in common carp spleens

(2020) Jianqing Chen et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Attenuation of Lipopolysaccharide-Induced Acute Lung Injury by Hispolon in Mice, Through Regulating the TLR4/PI3K/Akt/mTOR and Keap1/Nrf2/HO-1 Pathways, and Suppressing Oxidative Stress-Mediated ER Stress-Induced Apoptosis and Autophagy

(2020) Ching-Ying Huang et al.   Nutrients

The Interplay among miRNAs, Major Cytokines, and Cancer-Related Inflammation

(2020) Chiranjib Chakraborty et al.   Molecular Therapy-Nucleic Acids

2-Bromopalmitate attenuates inflammatory pain by maintaining mitochondrial fission/fusion balance and function

(2020) Min Xie et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

Chronic exposure of hydrogen peroxide alters redox state, apoptosis and endoplasmic reticulum stress in common carp (Cyprinus carpio)

(2020) Rui Jia et al.   AQUATIC TOXICOLOGY

Withaferin A inhibits lysosomal activity to block autophagic flux and induces apoptosis via energetic impairment in breast cancer cells

(2019) Nethaji Muniraj et al.   CARCINOGENESIS

Nicotine-mediated autophagy of vascular smooth muscle cell accelerates atherosclerosis via nAChRs/ROS/NF-κB signaling pathway

(2019) Zhiyan Wang et al.   ATHEROSCLEROSIS

Iron oxide nanoparticles promote macrophage autophagy and inflammatory response through activation of toll-like Receptor-4 signaling

(2019) Rongrong Jin et al.   BIOMATERIALS

MicroRNA-101a Regulates Autophagy Phenomenon via the MAPK Pathway to Modulate Alzheimer’s-Associated Pathogenesis

(2019) Qian Li et al.   CELL TRANSPLANTATION

Effects of Cr(VI) exposure on electrocardiogram, myocardial enzyme parameters, inflammatory factors, oxidative kinase, and ATPase of the heart in Chinese rural dogs

(2019) Jianwei Lu et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

LncRNA SOX2OT alleviates the high glucose-induced podocytes injury through autophagy induction by the miR-9/SIRT1 axis

(2019) Yan Zhang et al.   EXPERIMENTAL AND MOLECULAR PATHOLOGY

Regulation of autophagy factors by oxidative stress and cardiac enzymes imbalance during arsenic or/and copper induced cardiotoxicity in Gallus gallus

(2018) Siwen Li et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Mitochondrial DNA and TLR9 drive muscle inflammation upon Opa1 deficiency

(2018) Aida Rodríguez‐Nuevo et al.   EMBO JOURNAL

Trimethylamine-N-Oxide (TMAO)-Induced Impairment of Cardiomyocyte Function and the Protective Role of Urolithin B-Glucuronide

(2018) Monia Savi et al.   MOLECULES

The airway inflammation induced by nasal inoculation of PM2.5 and the treatment of bacterial lysates in rats

(2018) Yang Shen et al.   Scientific Reports

Impaired immune function and structural integrity in the gills of common carp (Cyprinus carpio L.) caused by chlorpyrifos exposure: Through oxidative stress and apoptosis

(2018) Wanying Jiao et al.   FISH & SHELLFISH IMMUNOLOGY

AMPK/PGC1α activation by melatonin attenuates acute doxorubicin cardiotoxicity via alleviating mitochondrial oxidative damage and apoptosis

(2018) Dong Liu et al.   FREE RADICAL BIOLOGY AND MEDICINE

Salidroside attenuates hypoxia-induced pulmonary arterial smooth muscle cell proliferation and apoptosis resistance by upregulating autophagy through the AMPK-mTOR-ULK1 pathway

(2017) Di Gui et al.   BMC Pulmonary Medicine

Cox-2 Inhibition Protects against Hypoxia/Reoxygenation-Induced Cardiomyocyte ApoptosisviaAkt-Dependent Enhancement of iNOS Expression

(2016) Lei Pang et al.   Oxidative Medicine and Cellular Longevity

Cardiac Energetic Impairment in Heart Disease and the Potential Role of Metabolic Modulators: A Review for Clinicians

(2014) S. Singh et al.   Circulation-Cardiovascular Genetics

TNF-α blockade induces IL-10 expression in human CD4+ T cells

(2014) Hayley G. Evans et al.   Nature Communications

SIRT1 activator (SRT1720) improves the follicle reserve and prolongs the ovarian lifespan of diet-induced obesity in female mice via activating SIRT1 and suppressing mTOR signaling

(2014) Xiao-Ling Zhou et al.   Journal of Ovarian Research

TGF-β1 Downregulates COX-2 Expression Leading to Decrease of PGE2 Production in Human Lung Cancer A549 Cells, Which Is Involved in Fibrotic Response to TGF-β1

(2013) Erina Takai et al.   PLoS One

Carcinoma cells activate AMP-activated protein kinase-dependent autophagy as survival response to kaempferol-mediated energetic impairment

(2010) Giuseppe Filomeni et al.   Autophagy

TNF-α modulates iNOS expression in an experimental rat model of indomethacin-induced jejunoileitis

(2009) Jyotirmoy Nandi et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY