TGF-β1 Downregulates COX-2 Expression Leading to Decrease of PGE2 Production in Human Lung Cancer A549 Cells, Which Is Involved in Fibrotic Response to TGF-β1

Title
TGF-β1 Downregulates COX-2 Expression Leading to Decrease of PGE2 Production in Human Lung Cancer A549 Cells, Which Is Involved in Fibrotic Response to TGF-β1
Authors
Keywords
COX-2 inhibitors, Lung and intrathoracic tumors, Messenger RNA, Actins, Fibrosis, Gene expression, Enzyme-linked immunoassays, Non-small cell lung cancer
Journal
PLoS One
Volume 8, Issue 10, Pages e76346
Publisher
Public Library of Science (PLoS)
Online
2013-10-03
DOI
10.1371/journal.pone.0076346

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