Polystyrene microplastics-induced cardiotoxicity in chickens via the ROS-driven NF-κB-NLRP3-GSDMD and AMPK-PGC-1α axes

Thioredoxin reductase 3 suppression promotes colitis and carcinogenesis via activating pyroptosis and necrosis

(2022) Qi Liu et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

The antagonistic effect of selenium on lead-induced apoptosis and necroptosis via P38/JNK/ERK pathway in chicken kidney

(2022) Zhiruo Miao et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

TMT induces apoptosis and necroptosis in mouse kidneys through oxidative stress-induced activation of the NLRP3 inflammasome

(2022) Xiao-Jing Liu et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Lithium intoxication induced pyroptosis via ROS / NF‐κB / NLRP3 inflammasome regulatory networks in kidney of mice

(2022) Hongyuan Jing et al.   ENVIRONMENTAL TOXICOLOGY

Polystyrene nanoplastics penetrate across the blood-brain barrier and induce activation of microglia in the brain of mice

(2022) Shan Shan et al.   CHEMOSPHERE

MiR-1656 targets GPX4 to trigger pyroptosis in broilers kidney tissues by activating NLRP3 inflammasome under Se deficiency

(2022) Xuedie Gu et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Lycopene Ameliorates Di(2-ethylhexyl) Phthalate-Induced Pyroptosis in Spleen via Suppression of Classic Caspase-1/NLRP3 Pathway

(2021) Xue-Yan Dai et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Classifying human influences on terrestrial ecosystems

(2021) Matthias C. Rillig et al.   GLOBAL CHANGE BIOLOGY

Environmentally relevant concentrations of microplastics influence the locomotor activity of aquatic biota

(2021) Tao Sun et al.   JOURNAL OF HAZARDOUS MATERIALS

The Kidney-Related Effects of Polystyrene Microplastics on Human Kidney Proximal Tubular Epithelial Cells HK-2 and Male C57BL/6 Mice

(2021) Yung-Li Wang et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Environmentally relevant concentration of sulfamethoxazole-induced oxidative stress-cascaded damages in the intestine of grass carp and the therapeutic application of exogenous lycopene

(2021) Yu Wang et al.   ENVIRONMENTAL POLLUTION

ROS-Induced Hepatotoxicity under Cypermethrin: Involvement of the Crosstalk between Nrf2/Keap1 and NF-κB/iκB-α Pathways Regulated by Proteasome

(2021) Hongjing Zhao et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Micro/nanoplastic mediated pathophysiological changes in rodents, rabbits, and chicken

(2021) Amrita Banerjee et al.   JOURNAL OF FOOD PROTECTION

NLRP3 inflammasome mediated pyroptosis is involved in cadmium exposure-induced neuroinflammation through the IL-1β/IkB-α-NF-κB-NLRP3 feedback loop in swine

(2021) Jingzeng Cai et al.   TOXICOLOGY

Effect of microplastics on aquatic biota: A hormetic perspective

(2021) Tao Sun et al.   ENVIRONMENTAL POLLUTION

PGC1s and Beyond: Disentangling the Complex Regulation of Mitochondrial and Cellular Metabolism

(2021) Lara Coppi et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Adverse effects polystyrene microplastics exert on zebrafish heart – Molecular to individual level

(2021) Anastasia Dimitriadi et al.   JOURNAL OF HAZARDOUS MATERIALS

Polystyrene microplastics trigger hepatocyte apoptosis and abnormal glycolytic flux via ROS-driven calcium overload

(2021) Siwen Li et al.   JOURNAL OF HAZARDOUS MATERIALS

A comparative review of microplastics and nanoplastics: Toxicity hazards on digestive, reproductive and nervous system

(2021) Kai Yin et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Microplastics in soil: A review on methods, occurrence, sources, and potential risk

(2021) Ling Yang et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Ecotoxicological Effects of Microplastics on Bird Embryo Development by Hatching without Eggshell

(2021) Liyi Wang et al.   Jove-Journal of Visualized Experiments

Prolonged oral ingestion of microplastics induced inflammation in the liver tissues of C57BL/6J mice through polarization of macrophages and increased infiltration of natural killer cells

(2021) Liangtao Zhao et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

H2S exposure induces cell death in the broiler thymus via the ROS-initiated JNK/MST1/FOXO1 pathway

(2021) Qianru Chi et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Pig lung fibrosis is active in the subacute CdCl2 exposure model and exerts cumulative toxicity through the M1/M2 imbalance

(2021) Shi Xu et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Glyphosate damages blood-testis barrier via NOX1-triggered oxidative stress in rats: Long-term exposure as a potential risk for male reproductive health

(2021) Jing-Bo Liu et al.   ENVIRONMENT INTERNATIONAL

Polystyrene microplastics disrupt the blood-testis barrier integrity through ROS-Mediated imbalance of mTORC1 and mTORC2

(2021) Yuexin Wei et al.   ENVIRONMENTAL POLLUTION

Exposure to imidacloprid induce oxidative stress, mitochondrial dysfunction, inflammation, apoptosis and mitophagy via NF-kappaB/JNK pathway in grass carp hepatocytes

(2021) Zhiruo Miao et al.   FISH & SHELLFISH IMMUNOLOGY

Cadmium exposure triggers oxidative stress, necroptosis, Th1/Th2 imbalance and promotes inflammation through the TNF-α/NF-κB pathway in swine small intestine

(2021) Xiaoming Chen et al.   JOURNAL OF HAZARDOUS MATERIALS

Epigenetic regulator BRD4 is involved in cadmium-induced acute kidney injury via contributing to lysosomal dysfunction, autophagy blockade and oxidative stress

(2021) Zhong-Gui Gong et al.   JOURNAL OF HAZARDOUS MATERIALS

Chlorpyrifos triggers epithelioma papulosum cyprini cell pyroptosis via miR-124-3p/CAPN1 axis

(2021) Zhiying Miao et al.   JOURNAL OF HAZARDOUS MATERIALS

Microplastics pollution and risk assessment in water bodies of two nature reserves in Jilin Province: Correlation analysis with the degree of human activity

(2021) Kai Yin et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Hydrogen Sulfide Promotes Cardiomyocyte Proliferation and Heart Regeneration via ROS Scavenging

(2020) Jianqiu Pei et al.   Oxidative Medicine and Cellular Longevity

The plastic brain: neurotoxicity of micro- and nanoplastics

(2020) Minne Prüst et al.   Particle and Fibre Toxicology

Polystyrene microplastics cause cardiac fibrosis by activating Wnt/β-catenin signaling pathway and promoting cardiomyocyte apoptosis in rats

(2020) Zekang Li et al.   ENVIRONMENTAL POLLUTION

Reproductive toxicity of polystyrene microplastics: In vivo experimental study on testicular toxicity in mice

(2020) Baolian Hou et al.   JOURNAL OF HAZARDOUS MATERIALS

Polystyrene microplastics cause granulosa cells apoptosis and fibrosis in ovary through oxidative stress in rats

(2020) Ru An et al.   TOXICOLOGY

Lipopolysaccharide (LPS) Aggravates High Glucose- and Hypoxia/Reoxygenation-Induced Injury through Activating ROS-Dependent NLRP3 Inflammasome-Mediated Pyroptosis in H9C2 Cardiomyocytes

(2019) Zhen Qiu et al.   Journal of Diabetes Research

Mono-(2-ethylhexyl) Phthalate Aggravates Inflammatory Response via Sirtuin Regulation and Inflammasome Activation in RAW 264.7 Cells

(2019) Min Hi Park et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Reactive Oxygen Species (ROS)-Based Nanomedicine

(2019) Bowen Yang et al.   CHEMICAL REVIEWS

Propofol directly induces caspase-1-dependent macrophage pyroptosis through the NLRP3-ASC inflammasome

(2019) Lingbin Sun et al.   Cell Death & Disease

Detection of Various Microplastics in Human Stool

(2019) Philipp Schwabl et al.   ANNALS OF INTERNAL MEDICINE

Assessment of microplastics in freshwater systems: A review

(2019) Chaoran Li et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Microplastics in aquatic environments: Occurrence, accumulation, and biological effects

(2019) Shen Xu et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Uptake, tissue distribution, and toxicity of polystyrene nanoparticles in developing zebrafish ( Danio rerio )

(2018) Jordan A. Pitt et al.   AQUATIC TOXICOLOGY

Maduramicin induces apoptosis in chicken myocardial cells via intrinsic and extrinsic pathways

(2018) Xiuge Gao et al.   TOXICOLOGY IN VITRO

Plastic and Human Health: A Micro Issue?

(2017) Stephanie L. Wright et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Pyroptosis: Gasdermin-Mediated Programmed Necrotic Cell Death

(2017) Jianjin Shi et al.   TRENDS IN BIOCHEMICAL SCIENCES

Are Agricultural Soils Dumps for Microplastics of Urban Origin?

(2016) Luca Nizzetto et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Uptake and Accumulation of Polystyrene Microplastics in Zebrafish (Danio rerio) and Toxic Effects in Liver

(2016) Yifeng Lu et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

RIPK1 counteracts ZBP1-mediated necroptosis to inhibit inflammation

(2016) Juan Lin et al.   NATURE

Pollutants bioavailability and toxicological risk from microplastics to marine mussels

(2015) Carlo Giacomo Avio et al.   ENVIRONMENTAL POLLUTION

Calcium signaling and mitochondrial destabilization in the triggering of the NLRP3 inflammasome

(2014) Tiffany Horng   TRENDS IN IMMUNOLOGY

The physical impacts of microplastics on marine organisms: A review

(2013) Stephanie L. Wright et al.   ENVIRONMENTAL POLLUTION

A Novel Paradigm for Heart Failure With Preserved Ejection Fraction

(2013) Walter J. Paulus et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Programmed Necrosis, Not Apoptosis, in the Heart

(2011) Gloria Kung et al.   CIRCULATION RESEARCH

Exposure to Hydrogen Peroxide Induces Oxidation and Activation of AMP-activated Protein Kinase

(2010) Jaroslaw W. Zmijewski et al.   JOURNAL OF BIOLOGICAL CHEMISTRY