Traumatic acid inhibits ACSL4 associated lipid accumulation in adipocytes to attenuate high‐fat diet‐induced obesity

Adipose-specific deletion of the cation channel TRPM7 inhibits TAK1 kinase-dependent inflammation and obesity in male mice

(2023) Weiting Zhong et al.   Nature Communications

Diet-induced loss of adipose hexokinase 2 correlates with hyperglycemia

(2023) Mitsugu Shimobayashi et al.   eLife

ACSL4 Directs Intramuscular Adipogenesis and Fatty Acid Composition in Pigs

(2022) Hongyan Ren et al.   Animals

A 2022 update on the epidemiology of obesity and a call to action: as its twin COVID-19 pandemic appears to be receding, the obesity and dysmetabolism pandemic continues to rage on

(2022) Chrysoula Boutari et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

CRISPR/Cas9 Screens Reveal that Hexokinase 2 Enhances Cancer Stemness and Tumorigenicity by Activating the ACSL4‐Fatty Acid β ‐Oxidation Pathway

(2022) Hongquan Li et al.   Advanced Science

Ferroptosis turns 10: Emerging mechanisms, physiological functions, and therapeutic applications

(2022) Brent R. Stockwell   CELL

Evening chronotype is associated with severe NAFLD in obesity

(2022) Claudia Vetrani et al.   INTERNATIONAL JOURNAL OF OBESITY

Therapeutic Potential of Plant Oxylipins

(2022) Tatyana Savchenko et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The phytochemical hyperforin triggers thermogenesis in adipose tissue via a Dlat-AMPK signaling axis to curb obesity

(2021) Suzhen Chen et al.   Cell Metabolism

Administration of isoliquiritigenin prevents nonalcoholic fatty liver disease through a novel IQGAP2‐CREB‐SIRT1 axis

(2021) Li Zhang et al.   PHYTOTHERAPY RESEARCH

Ferroptotic cell death triggered by conjugated linolenic acids is mediated by ACSL1

(2021) Alexander Beatty et al.   Nature Communications

Therapeutic Targeting of Hepatic ACSL4 Ameliorates Non‐alcoholic Steatohepatitis in Mice

(2021) Jingjing Duan et al.   HEPATOLOGY

Identification of plant-based hexokinase 2 inhibitors: combined molecular docking and dynamics simulation studies

(2021) Asifa Khan et al.   JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS

Epidemiology and determinants of obesity in China

(2021) Xiong-Fei Pan et al.   Lancet Diabetes & Endocrinology

Predictive and prognostic impact of ferroptosis-related genes ACSL4 and GPX4 on breast cancer treated with neoadjuvant chemotherapy

(2021) Rui Sha et al.   EBioMedicine

Identification of traumatic acid as a potential plasma biomarker for sarcopenia using a metabolomics‐based approach

(2021) Jaw‐Shiun Tsai et al.   Journal of Cachexia Sarcopenia and Muscle

miR-34a regulates adipogenesis in porcine intramuscular adipocytes by targeting ACSL4

(2020) Wenwen Wang et al.   BMC GENETICS

Possible Protective Effects of TA on the Cancerous Effect of Mesotrione

(2020) Agata Jabłońska-Trypuć et al.   Nutrients

Long-chain acyl-CoA synthetase 4-mediated fatty acid metabolism sustains androgen receptor pathway-independent prostate cancer

(2020) Yongjie Ma et al.   MOLECULAR CANCER RESEARCH

Plant extracts in prevention of obesity

(2020) Han-Ning Wang et al.   CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION

Identification of Milk Fat Metabolism-Related Pathways of the Bovine Mammary Gland during Mid and Late Lactation and Functional Verification of the ACSL4 Gene

(2020) Yongliang Fan et al.   Genes

ACSL4 reprograms fatty acid metabolism in hepatocellular carcinoma via c-Myc/SREBP1 pathway

(2020) Junru Chen et al.   CANCER LETTERS

Toxicological Effects of Traumatic Acid and Selected Herbicides on Human Breast Cancer Cells: In Vitro Cytotoxicity Assessment of Analyzed Compounds

(2019) Agata Jabłońska-Trypuć et al.   MOLECULES

Traumatic acid toxicity mechanisms in human breast cancer MCF-7 cells

(2019) Agata Jabłońska-Trypuć et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

A network-based approach to identify deregulated pathways and drug effects in metabolic syndrome

(2019) Karla Misselbeck et al.   Nature Communications

Glutamine Links Obesity to Inflammation in Human White Adipose Tissue

(2019) Paul Petrus et al.   Cell Metabolism

UPLC–QTOF-MS-Based Plasma Lipidomic Profiling Reveals Biomarkers for Inflammatory Bowel Disease Diagnosis

(2019) Su Guan et al.   JOURNAL OF PROTEOME RESEARCH

A role for long-chain acyl-CoA synthetase-4 (ACSL4) in diet-induced phospholipid remodeling and obesity-associated adipocyte dysfunction

(2018) Elizabeth A. Killion et al.   Molecular Metabolism

Topical Application of Adelmidrol + Trans-Traumatic Acid Enhances Skin Wound Healing in a Streptozotocin-Induced Diabetic Mouse Model

(2018) Rosalba Siracusa et al.   Frontiers in Pharmacology

Adipose Cell Size and Regional Fat Deposition as Predictors of Metabolic Response to Overfeeding in Insulin-Resistant and Insulin-Sensitive Humans

(2016) Tracey McLaughlin et al.   DIABETES

Traumatic Acid Reduces Oxidative Stress and Enhances Collagen Biosynthesis in Cultured Human Skin Fibroblasts

(2016) Agata Jabłońska-Trypuć et al.   LIPIDS

ACSL4 dictates ferroptosis sensitivity by shaping cellular lipid composition

(2016) Sebastian Doll et al.   Nature Chemical Biology

Rational Design of Small Molecule Inhibitors Targeting the Ras GEF, SOS1

(2014) Chris R. Evelyn et al.   CHEMISTRY & BIOLOGY

Gene expression profiling of subcutaneous adipose tissue in morbid obesity using a focused microarray: Distinct expression of cell-cycle- and differentiation-related genes

(2011) Sara Rodríguez-Acebes et al.   BMC Medical Genomics

Protein-binding assays in biological liquids using microscale thermophoresis

(2010) Christoph J. Wienken et al.   Nature Communications