The phytochemical hyperforin triggers thermogenesis in adipose tissue via a Dlat-AMPK signaling axis to curb obesity

Trans-Cinnamic Acid Stimulates White Fat Browning and Activates Brown Adipocytes

(2019) Nam Kang et al.   Nutrients

Next-Generation Phenotypic Screening in Early Drug Discovery for Infectious Diseases

(2019) Nathalie Aulner et al.   TRENDS IN PARASITOLOGY

A Map of Protein-Metabolite Interactions Reveals Principles of Chemical Communication

(2018) Ilaria Piazza et al.   CELL

CalR : A Web-Based Analysis Tool for Indirect Calorimetry Experiments

(2018) Amir I. Mina et al.   Cell Metabolism

Meta-analysis of genome-wide association studies for body fat distribution in 694,649 individuals of European ancestry

(2018) Sara L Pulit et al.   HUMAN MOLECULAR GENETICS

Discovery of Novel and Selective Adenosine A2A Receptor Antagonists for Treating Parkinson’s Disease through Comparative Structure-Based Virtual Screening

(2017) Sheng Tian et al.   Journal of Chemical Information and Modeling

Prospective Evaluation of Free Energy Calculations for the Prioritization of Cathepsin L Inhibitors

(2017) Bernd Kuhn et al.   JOURNAL OF MEDICINAL CHEMISTRY

Thyroid hormones and browning of adipose tissue

(2017) Juliane Weiner et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

UCP1-independent signaling involving SERCA2b-mediated calcium cycling regulates beige fat thermogenesis and systemic glucose homeostasis

(2017) Kenji Ikeda et al.   NATURE MEDICINE

Factors involved in white-to-brown adipose tissue conversion and in thermogenesis: a review

(2017) T. Montanari et al.   Obesity Reviews

UCP1 deficiency causes brown fat respiratory chain depletion and sensitizes mitochondria to calcium overload-induced dysfunction

(2017) Lawrence Kazak et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cell-wide analysis of protein thermal unfolding reveals determinants of thermostability

(2017) Pascal Leuenberger et al.   SCIENCE

Inflammation Improves Glucose Homeostasis through IKKβ-XBP1s Interaction

(2016) Junli Liu et al.   CELL

iNKT Cells Induce FGF21 for Thermogenesis and Are Required for Maximal Weight Loss in GLP1 Therapy

(2016) Lydia Lynch et al.   Cell Metabolism

Lack of Adipocyte AMPK Exacerbates Insulin Resistance and Hepatic Steatosis through Brown and Beige Adipose Tissue Function

(2016) Emilio P. Mottillo et al.   Cell Metabolism

Beta3-adrenoreceptor agonist mirabegron – a potential antiobesity drug?

(2016) Vojtech Hainer   EXPERT OPINION ON PHARMACOTHERAPY

Chronic AMPK activation via loss of FLCN induces functional beige adipose tissue through PGC-1α/ERRα

(2016) Ming Yan et al.   GENES & DEVELOPMENT

Withaferin A is a leptin sensitizer with strong antidiabetic properties in mice

(2016) Jaemin Lee et al.   NATURE MEDICINE

Wasting Energy to Treat Obesity

(2016) Paul Lee   NEW ENGLAND JOURNAL OF MEDICINE

Influencing Factors of Thermogenic Adipose Tissue Activity

(2016) Guoqing Zhang et al.   Frontiers in Physiology

Treatment of Obesity with Celastrol

(2015) Junli Liu et al.   CELL

A Creatine-Driven Substrate Cycle Enhances Energy Expenditure and Thermogenesis in Beige Fat

(2015) Lawrence Kazak et al.   CELL

MicroRNA-455 regulates brown adipogenesis via a novel HIF1an-AMPK-PGC1  signaling network

(2015) H. Zhang et al.   EMBO REPORTS

Limited Proteolysis Combined with Stable Isotope Labeling Reveals Conformational Changes in Protein (Pseudo)kinases upon Binding Small Molecules

(2015) Michela Di Michele et al.   JOURNAL OF PROTEOME RESEARCH

limma powers differential expression analyses for RNA-sequencing and microarray studies

(2015) Matthew E. Ritchie et al.   NUCLEIC ACIDS RESEARCH

What We Talk About When We Talk About Fat

(2014) Evan D. Rosen et al.   CELL

GLP-1 Agonism Stimulates Brown Adipose Tissue Thermogenesis and Browning Through Hypothalamic AMPK

(2014) D. Beiroa et al.   DIABETES

Accurate Proteome-wide Label-free Quantification by Delayed Normalization and Maximal Peptide Ratio Extraction, Termed MaxLFQ

(2014) Jürgen Cox et al.   MOLECULAR & CELLULAR PROTEOMICS

Dietary factors evoke thermogenesis in adipose tissues

(2014) Tomoya Sakamoto et al.   Obesity Research & Clinical Practice

Berberine activates thermogenesis in white and brown adipose tissue

(2014) Zhiguo Zhang et al.   Nature Communications

Irisin Stimulates Browning of White Adipocytes Through Mitogen-Activated Protein Kinase p38 MAP Kinase and ERK MAP Kinase Signaling

(2013) Y. Zhang et al.   DIABETES

Evidence for the role of AMPK in regulating PGC-1 alpha expression and mitochondrial proteins in mouse epididymal adipose tissue

(2013) Zhongxiao Wan et al.   Obesity

Fat cells directly sense temperature to activate thermogenesis

(2013) L. Ye et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

BMP8B Increases Brown Adipose Tissue Thermogenesis through Both Central and Peripheral Actions

(2012) Andrew J. Whittle et al.   CELL

Applications of Connectivity Map in drug discovery and development

(2012) Xiaoyan A. Qu et al.   DRUG DISCOVERY TODAY

Agonistic Autoantibodies as Vasodilators in Orthostatic Hypotension

(2012) Hongliang Li et al.   HYPERTENSION

NIH Image to ImageJ: 25 years of image analysis

(2012) Caroline A Schneider et al.   NATURE METHODS

AICAR and Compound C regulate food intake independently of AMP-activated protein kinase in lines of chickens selected for high or low body weight

(2011) Pingwen Xu et al.   COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY A-MOLECULAR & INTEGRATIVE PHYSIOLOGY

HaploReg: a resource for exploring chromatin states, conservation, and regulatory motif alterations within sets of genetically linked variants

(2011) L. D. Ward et al.   NUCLEIC ACIDS RESEARCH

LocusZoom: regional visualization of genome-wide association scan results

(2010) R. J. Pruim et al.   BIOINFORMATICS

Adenosine 5′-Monophosphate-Activated Protein Kinase-Mammalian Target of Rapamycin Cross Talk Regulates Brown Adipocyte Differentiation

(2010) Rocio Vila-Bedmar et al.   ENDOCRINOLOGY

To eat or not to eat: the effect of AICAR on food intake regulation in yellow-bellied marmots (Marmota flaviventris)

(2010) G. L. Florant et al.   JOURNAL OF EXPERIMENTAL BIOLOGY

Hypoxia-Independent Angiogenesis in Adipose Tissues during Cold Acclimation

(2009) Yuan Xue et al.   Cell Metabolism

Interaction of E1 and E3 components with the core proteins of the human pyruvate dehydrogenase complex

(2009) Mulchand S. Patel et al.   JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC

Target identification using drug affinity responsive target stability (DARTS)

(2009) B. Lomenick et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA