Connective tissue growth factor: Role in trabecular meshwork remodeling and intraocular pressure lowering
Published 2023 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Connective tissue growth factor: Role in trabecular meshwork remodeling and intraocular pressure lowering
Authors
Keywords
-
Journal
EXPERIMENTAL BIOLOGY AND MEDICINE
Volume -, Issue -, Pages -
Publisher
SAGE Publications
Online
2023-10-24
DOI
10.1177/15353702231199466
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Activation of the ATX/LPA/LPARs axis induces a fibrotic response in skeletal muscle
- (2022) Adriana Córdova-Casanova et al. MATRIX BIOLOGY
- Extracellular Matrix Stiffness and TGFβ2 Regulate YAP/TAZ Activity in Human Trabecular Meshwork Cells
- (2022) Haiyan Li et al. Frontiers in Cell and Developmental Biology
- Intravitreal connective tissue growth factor neutralizing antibody or bevacizumab alone or in combination for prevention of proliferative vitreoretinopathy in an experimental model
- (2021) Narsis Daftarian et al. EXPERIMENTAL EYE RESEARCH
- JNK and p38 Inhibitors Prevent Transforming Growth Factor-β1-Induced Myofibroblast Transdifferentiation in Human Graves’ Orbital Fibroblasts
- (2021) Tzu-Yu Hou et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- YAP, CTGF, and Cyr61 are overexpressed in tamoxifen-resistant breast cancer and induce transcriptional repression of ERα
- (2021) Hyungjoo Kim et al. JOURNAL OF CELL SCIENCE
- FoxO1 is required for high glucose-dependent cardiac fibroblasts into myofibroblast phenoconversion
- (2021) Raúl Vivar et al. CELLULAR SIGNALLING
- Pamrevlumab for the treatment of idiopathic pulmonary fibrosis
- (2020) Giacomo Sgalla et al. EXPERT OPINION ON INVESTIGATIONAL DRUGS
- Treatment of glaucoma by prostaglandin agonists and beta‐blockers in combination directly reduces pro‐fibrotic gene expression in trabecular meshwork
- (2020) Sushma Tejwani et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- The control of conjunctival fibrosis as a paradigm for the prevention of ocular fibrosis-related blindness. “Fibrosis has many friends”
- (2020) Peng Tee Khaw et al. EYE
- TGF-β Induced CTGF Expression in Human Lung Epithelial Cells through ERK, ADAM17, RSK1, and C/EBPβ Pathways
- (2020) Shu-Ching Ou et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- CTGF-mediated ERK signaling pathway influences the inflammatory factors and intestinal flora in ulcerative colitis
- (2019) Zhen-Mei Song et al. BIOMEDICINE & PHARMACOTHERAPY
- Effect of Timolol on Aqueous Humor Outflow Facility in Healthy Human Eyes
- (2019) Arash Kazemi et al. AMERICAN JOURNAL OF OPHTHALMOLOGY
- Epigenetic activation of CTGF transcription by high glucose in renal tubular epithelial cells is mediated by myocardin-related transcription factor A
- (2019) Jing Shao et al. CELL AND TISSUE RESEARCH
- Role of hypoxia in skeletal muscle fibrosis: Synergism between hypoxia and TGF-β signaling upregulates CCN2/CTGF expression specifically in muscle fibers
- (2019) Roger Valle-Tenney et al. MATRIX BIOLOGY
- Expression of CTGF/CCN2 in response to LPA is stimulated by fibrotic extracellular matrix via the integrin/FAK axis
- (2018) Camilo Riquelme-Guzmán et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- Connective tissue growth factor stimulates osteosarcoma cell migration and induces osteosarcoma metastasis by upregulating VCAM-1 expression
- (2018) Chun-Han Hou et al. BIOCHEMICAL PHARMACOLOGY
- CTGF mediates tumor-stroma interactions between hepatoma cells and hepatic stellate cells to accelerate HCC progression.
- (2018) Yuki Makino et al. CANCER RESEARCH
- Rho-Kinase Induces CTGF Expression through Actin Dynamics in Mesangial Cells
- (2018) YOSUKE NAGAI et al. DIABETES
- Netarsudil Ophthalmic Solution 0.02%: First Global Approval
- (2018) Sheridan M. Hoy DRUGS
- Pirfenidone prevents radiation-induced intestinal fibrosis in rats by inhibiting fibroblast proliferation and differentiation and suppressing the TGF-β1/Smad/CTGF signaling pathway
- (2018) Yan-Wu Sun et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- YAP/TAZ Signaling as a Molecular Link between Fibrosis and Cancer
- (2018) Satoshi Noguchi et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Intracameral Delivery of Layer‐by‐Layer Coated siRNA Nanoparticles for Glaucoma Therapy
- (2018) Andrea E. Dillinger et al. Small
- Trabecular meshwork stiffness in glaucoma
- (2017) Ke Wang et al. EXPERIMENTAL EYE RESEARCH
- Role of the Rho GTPase/Rho kinase signaling pathway in pathogenesis and treatment of glaucoma: Bench to bedside research
- (2017) Ponugoti Vasantha Rao et al. EXPERIMENTAL EYE RESEARCH
- Smad-independent TGF-β2 signaling pathways in human trabecular meshwork cells
- (2017) Cynthia L. Pervan EXPERIMENTAL EYE RESEARCH
- Neuronal CTGF/CCN2 negatively regulates myelination in a mouse model of tuberous sclerosis complex
- (2017) Ebru Ercan et al. JOURNAL OF EXPERIMENTAL MEDICINE
- FOSL1 Inhibits Type I Interferon Responses to Malaria and Viral Infections by Blocking TBK1 and TRAF3/TRIF Interactions
- (2017) Baowei Cai et al. mBio
- Enhancement of Outflow Facility in the Murine Eye by Targeting Selected Tight-Junctions of Schlemm’s Canal Endothelia
- (2017) Lawrence C. S. Tam et al. Scientific Reports
- Epigenetics and Signaling Pathways in Glaucoma
- (2017) Angela C. Gauthier et al. Biomed Research International
- The JNK Signaling Pathway in Renal Fibrosis
- (2017) Keren Grynberg et al. Frontiers in Physiology
- Immunohistochemical Detection of CTGF in the Human Eye
- (2016) Gysbert B. van Setten et al. CURRENT EYE RESEARCH
- TGF-β1, in association with the increased expression of connective tissue growth factor, induce the hypertrophy of the ligamentum flavum through the p38 MAPK pathway
- (2016) Yan-Lin Cao et al. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
- Comparative Effectiveness of First-Line Medications for Primary Open-Angle Glaucoma
- (2016) Tianjing Li et al. OPHTHALMOLOGY
- FG-3019, a Human Monoclonal Antibody Recognizing Connective Tissue Growth Factor, is Subject to Target-Mediated Drug Disposition
- (2016) Mitchell C. Brenner et al. PHARMACEUTICAL RESEARCH
- Vascular Endothelial Growth Factor-A Increases the Aqueous Humor Outflow Facility
- (2016) Tomokazu Fujimoto et al. PLoS One
- Signaling Cross Talk between TGF-β/Smad and Other Signaling Pathways
- (2016) Kunxin Luo Cold Spring Harbor Perspectives in Biology
- Non-Smad Signaling Pathways of the TGF-β Family
- (2016) Ying E. Zhang Cold Spring Harbor Perspectives in Biology
- The Overexpression of TGF-β and CCN2 in Intrauterine Adhesions Involves the NF-κB Signaling Pathway
- (2016) Xiang Xue et al. PLoS One
- Mechanosignaling through YAP and TAZ drives fibroblast activation and fibrosis
- (2015) Fei Liu et al. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
- Global variations and time trends in the prevalence of primary open angle glaucoma (POAG): a systematic review and meta-analysis
- (2015) Venediktos V Kapetanakis et al. BRITISH JOURNAL OF OPHTHALMOLOGY
- Connective tissue growth factor regulates cardiac function and tissue remodeling in a mouse model of dilated cardiomyopathy
- (2015) Yevgeniya E. Koshman et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Inflammatory microenvironment and tumor necrosis factor alpha as modulators of periostin and CCN2 expression in human non-healing skin wounds and dermal fibroblasts
- (2015) Christopher G. Elliott et al. MATRIX BIOLOGY
- AFAP1 Is a Novel Downstream Mediator of TGF-β1 for CCN2 Induction in Osteoblasts
- (2015) Youngjin Cho et al. PLoS One
- MicroRNA-29b Inhibits Endometrial Fibrosis by Regulating the Sp1-TGF-β1/Smad-CTGF Axis in a Rat Model
- (2015) Jingxiong Li et al. Reproductive Sciences
- p38 MAP Kinase Inhibitor Suppresses Transforming Growth Factor-β2–Induced Type 1 Collagen Production in Trabecular Meshwork Cells
- (2015) Miyuki Inoue-Mochita et al. PLoS One
- Connective-Tissue Growth Factor (CTGF/CCN2) Induces Astrogenesis and Fibronectin Expression of Embryonic Neural Cells In Vitro
- (2015) Fabio A. Mendes et al. PLoS One
- Alteration of Connective Tissue Growth Factor (CTGF) Expression in Orbital Fibroblasts from Patients with Graves’ Ophthalmopathy
- (2015) Chieh-Chih Tsai et al. PLoS One
- CTGF increases matrix metalloproteinases expression and subsequently promotes tumor metastasis in human osteosarcoma through down-regulating miR-519d
- (2015) Hsiao-Chi Tsai et al. Oncotarget
- Ripasudil: First Global Approval
- (2014) Karly P. Garnock-Jones DRUGS
- Effect of pirfenidone on proliferation, TGF-β-induced myofibroblast differentiation and fibrogenic activity of primary human lung fibroblasts
- (2014) Enrico Conte et al. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
- The Pathophysiology and Treatment of Glaucoma
- (2014) Robert N. Weinreb et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- The Biology of YAP/TAZ: Hippo Signaling and Beyond
- (2014) Stefano Piccolo et al. PHYSIOLOGICAL REVIEWS
- Transforming growth factor β induces expression of connective tissue growth factor in hepatic progenitor cells through Smad independent signaling
- (2013) Ze-yang Ding et al. CELLULAR SIGNALLING
- Physiological roles of Rho and Rho effectors in mammals
- (2013) Dean Thumkeo et al. EUROPEAN JOURNAL OF CELL BIOLOGY
- Reducing CTGF/CCN2 slows down mdx muscle dystrophy and improves cell therapy
- (2013) Maria Gabriela Morales et al. HUMAN MOLECULAR GENETICS
- Hypoxia-inducible Factor (HIF)-1α and CCN2 Form a Regulatory Circuit in Hypoxic Nucleus Pulposus Cells
- (2013) Cassie M. Tran et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Rho-associated kinase inhibitors: A novel glaucoma therapy
- (2013) Toshihiro Inoue et al. PROGRESS IN RETINAL AND EYE RESEARCH
- CCN proteins: A centralized communication network
- (2013) Bernard Perbal Journal of Cell Communication and Signaling
- Cysteine-rich protein 61 (CCN1) and connective tissue growth factor (CCN2) at the crosshairs of ocular neovascular and fibrovascular disease therapy
- (2013) Lulu Yan et al. Journal of Cell Communication and Signaling
- Connective Tissue Growth Factor Causes Glaucoma by Modifying the Actin Cytoskeleton of the Trabecular Meshwork
- (2012) Benjamin Junglas et al. AMERICAN JOURNAL OF PATHOLOGY
- Cellular Mechanisms of Tissue Fibrosis. 1. Common and organ-specific mechanisms associated with tissue fibrosis
- (2012) Michael Zeisberg et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- The Skeletal site-specific role of connective tissue growth factor in prenatal osteogenesis
- (2012) Alex G. Lambi et al. DEVELOPMENTAL DYNAMICS
- Angiotensin II increases CTGF expression via MAPKs/TGF-β1/TRAF6 pathway in atrial fibroblasts
- (2012) Jun Gu et al. EXPERIMENTAL CELL RESEARCH
- CCN2/CTGF regulates neovessel formation via targeting structurally conserved cystine knot motifs in multiple angiogenic regulators
- (2012) Liya Pi et al. FASEB JOURNAL
- Mechanical stretch increases Smad3-dependent CCN2 expression in inner meniscus cells
- (2012) Takayuki Furumatsu et al. JOURNAL OF ORTHOPAEDIC RESEARCH
- Antiproliferative factor regulates connective tissue growth factor (CTGF/CCN2) expression in T24 bladder carcinoma cells
- (2012) Christina A. Matika et al. MOLECULAR BIOLOGY OF THE CELL
- Intraocular Pressure-Lowering Effects of Commonly Used Fixed-Combination Drugs with Timolol: A Systematic Review and Meta-Analysis
- (2012) Jin-Wei Cheng et al. PLoS One
- IFN-γ and TNF-α Synergize to Inhibit CTGF Expression in Human Lung Endothelial Cells
- (2012) Roderich Laug et al. PLoS One
- Promotion of Ccn2 expression and osteoblastic differentiation by actin polymerization, which is induced by laminar fluid flow stress
- (2012) Tadashi Honjo et al. Journal of Cell Communication and Signaling
- Connective tissue growth factor antagonizes transforming growth factor-β1/Smad signalling in renal mesangial cells
- (2011) Helen C. O'Donovan et al. BIOCHEMICAL JOURNAL
- Non-Smad signaling pathways
- (2011) Yabing Mu et al. CELL AND TISSUE RESEARCH
- Plasma CCN2 (connective tissue growth factor; CTGF) is a potential biomarker in idiopathic pulmonary fibrosis (IPF)
- (2011) Masato Kono et al. CLINICA CHIMICA ACTA
- Effect of CCN2 on FGF2-Induced Proliferation and MMP9 and MMP13 Productions by Chondrocytes
- (2011) Takashi Nishida et al. ENDOCRINOLOGY
- Decorin Interacts with Connective Tissue Growth Factor (CTGF)/CCN2 by LRR12 Inhibiting Its Biological Activity
- (2011) Cecilia Vial et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Short-interfering RNAs Induce Retinal Degeneration via TLR3 and IRF3
- (2011) Mark E Kleinman et al. MOLECULAR THERAPY
- Taking aim at the extracellular matrix: CCN proteins as emerging therapeutic targets
- (2011) Joon-Il Jun et al. NATURE REVIEWS DRUG DISCOVERY
- The CCN family: A new class of inflammation modulators?
- (2010) L. Kular et al. BIOCHIMIE
- Molecular signature of response and potential pathways related to resistance to the HSP90 inhibitor, 17AAG, in breast cancer
- (2010) Magdalena Zajac et al. BMC Medical Genomics
- Phase 1 Study of Anti-CTGF Monoclonal Antibody in Patients with Diabetes and Microalbuminuria
- (2010) S. G. Adler et al. Clinical Journal of the American Society of Nephrology
- Clinical Pharmacokinetics of Therapeutic Monoclonal Antibodies
- (2010) Ron J. Keizer et al. CLINICAL PHARMACOKINETICS
- Role of CCN, a vertebrate specific gene family, in development
- (2010) Ken-ichi Katsube et al. DEVELOPMENT GROWTH & DIFFERENTIATION
- The TAK1–TRAF6 signalling pathway
- (2010) Marene Landström INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- WISP-1/CCN4 regulates osteogenesis by enhancing BMP-2 activity
- (2010) Mitsuaki Ono et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Recent Progress in Chemically Modified siRNAs
- (2010) M. Gaglione et al. MINI-REVIEWS IN MEDICINAL CHEMISTRY
- The role of CTGF in the diabetic rat retina and its relationship with VEGF and TGF-β2, elucidated by treatment with CTGFsiRNA
- (2009) Hongwei Yang et al. ACTA OPHTHALMOLOGICA
- Adverse effects of high glucose and free fatty acid on cardiomyocytes are mediated by connective tissue growth factor
- (2009) Xiaoyu Wang et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- Pivotal role of connective tissue growth factor in lung fibrosis: MAPK-dependent transcriptional activation of type I collagen
- (2009) Markella Ponticos et al. ARTHRITIS AND RHEUMATISM
- Modulation of extracellular matrix turnover in the trabecular meshwork
- (2009) Rudolf Fuchshofer et al. EXPERIMENTAL EYE RESEARCH
- Connective tissue growth factor induces extracellular matrix deposition in human trabecular meshwork cells
- (2009) Benjamin Junglas et al. EXPERIMENTAL EYE RESEARCH
- Strategies for blocking the fibrogenic actions of connective tissue growth factor (CCN2): From pharmacological inhibition in vitro to targeted siRNA therapy in vivo
- (2009) David R. Brigstock Journal of Cell Communication and Signaling
- Novel molecular insights into RhoA GTPase-induced resistance to aqueous humor outflow through the trabecular meshwork
- (2008) Min Zhang et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- Pulmonary hypoplasia in the connective tissue growth factor (Ctgf) null mouse
- (2008) Mark Baguma-Nibasheka et al. DEVELOPMENTAL DYNAMICS
- The role of the actomyosin system in regulating trabecular fluid outflow
- (2008) Baohe Tian et al. EXPERIMENTAL EYE RESEARCH
- Connective tissue growth factor: Structure–function relationships of a mosaic, multifunctional protein
- (2008) Patricia De Winter et al. GROWTH FACTORS
- TRAF6 Mediates Smad-Independent Activation of JNK and p38 by TGF-β
- (2008) Motozo Yamashita et al. MOLECULAR CELL
- Sequence- and target-independent angiogenesis suppression by siRNA via TLR3
- (2008) Mark E. Kleinman et al. NATURE
- The type I TGF-β receptor engages TRAF6 to activate TAK1 in a receptor kinase-independent manner
- (2008) Alessandro Sorrentino et al. NATURE CELL BIOLOGY
- The CCN family of proteins: structure–function relationships
- (2008) Kenneth P. Holbourn et al. TRENDS IN BIOCHEMICAL SCIENCES
- Skeletal muscle cells express the profibrotic cytokine connective tissue growth factor (CTGF/CCN2), which induces their dedifferentiation
- (2007) Cecilia Vial et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Cell-penetrating Peptide for Enhanced Delivery of Nucleic Acids and Drugs to Ocular Tissues Including Retina and Cornea
- (2007) Leslie N Johnson et al. MOLECULAR THERAPY
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationFind the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
Search