Construction of a novel kinetic model for the production process of a CVA6 VLP vaccine in CHO cells

Differential N ‐ and O ‐glycosylation signatures of HIV‐1 Gag virus‐like particles and coproduced extracellular vesicles

(2022) Jesús Lavado‐García et al.   BIOTECHNOLOGY AND BIOENGINEERING

Model‐based workflow for scale‐up of process strategies developed in miniaturized bioreactor systems

(2021) Lukas Arndt et al.   BIOTECHNOLOGY PROGRESS

Towards in silico Process Modeling for Vaccines

(2021) Antonio Gaetano Cardillo et al.   TRENDS IN BIOTECHNOLOGY

Virus-like particles: preparation, immunogenicity and their roles as nanovaccines and drug nanocarriers

(2021) Saghi Nooraei et al.   JOURNAL OF NANOBIOTECHNOLOGY

Multi‐omics profiling of a CHO cell culture system unravels the effect of culture pH on cell growth, antibody titer, and product quality

(2021) Alison P. Lee et al.   BIOTECHNOLOGY AND BIOENGINEERING

A roadmap to AI-driven in silico process development: bioprocessing 4.0 in practice

(2021) Moritz von Stosch et al.   Current Opinion in Chemical Engineering

Bioprocess systems analysis, modeling, estimation, and control

(2021) Yu Luo et al.   Current Opinion in Chemical Engineering

A large-scale outbreak of hand, foot and mouth disease, France, as at 28 September 2021

(2021) Audrey Mirand et al.   Eurosurveillance

Sensitivity analysis methods in the biomedical sciences

(2020) George Qian et al.   MATHEMATICAL BIOSCIENCES

Dynamic Modeling of CHO Cell Metabolism Using the Hybrid Cybernetic Approach With a Novel Elementary Mode Analysis Strategy

(2020) Juan A. Martínez et al.   Frontiers in Bioengineering and Biotechnology

The ability to utilise ammonia as nitrogen source is cell type specific and intricately linked to GDH, AMPK and mTORC1

(2019) Shervi Lie et al.   Scientific Reports

Model-assisted Design of Experiments as a concept for knowledge-based bioprocess development

(2019) Johannes Möller et al.   BIOPROCESS AND BIOSYSTEMS ENGINEERING

Hybrid physics‐based and data‐driven modeling for bioprocess online simulation and optimization

(2019) Dongda Zhang et al.   BIOTECHNOLOGY AND BIOENGINEERING

A new generation of predictive models: The added value of hybrid models for manufacturing processes of therapeutic proteins

(2019) Harini Narayanan et al.   BIOTECHNOLOGY AND BIOENGINEERING

Mechanisms driving the lactate switch in Chinese hamster ovary cells

(2018) Fiona Hartley et al.   BIOTECHNOLOGY AND BIOENGINEERING

Systematic development of temperature shift strategies for Chinese hamster ovary cells based on short duration cultures and kinetic modeling

(2018) Jianlin Xu et al.   mAbs

Effects of ammonia on apoptosis and oxidative stress in bovine mammary epithelial cells

(2018) Fengge Wang et al.   MUTAGENESIS

Production of virus-like particles for vaccines

(2017) J. Fuenmayor et al.   New Biotechnology

Kinetic Modeling of Mammalian Cell Culture Bioprocessing: The Quest to Advance Biomanufacturing

(2017) Sarantos Kyriakopoulos et al.   Biotechnology Journal

Impact of cell lysis on the description of cell growth and death in cell culture

(2016) Paul Kroll et al.   ENGINEERING IN LIFE SCIENCES

Quantification of cell lysis during CHO bioprocesses: Impact on cell count, growth kinetics and productivity

(2015) Tobias Klein et al.   JOURNAL OF BIOTECHNOLOGY

Revisiting Verhulst and Monod models: analysis of batch and fed-batch cultures

(2014) Nishikant Shirsat et al.   CYTOTECHNOLOGY

Coxsackievirus A6 associated hand, foot and mouth disease in adults: Clinical presentation and review of the literature

(2014) Marigdalia K. Ramirez-Fort et al.   JOURNAL OF CLINICAL VIROLOGY

Recent advances in mammalian protein production

(2013) Ashok D. Bandaranayake et al.   FEBS LETTERS

Plant-derived virus-like particles as vaccines

(2012) Qiang Chen et al.   Human Vaccines & Immunotherapeutics

The largest outbreak of hand; foot and mouth disease in Singapore in 2008: The role of enterovirus 71 and coxsackievirus A strains

(2010) Yan Wu et al.   INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES

Virology, epidemiology, pathogenesis, and control of enterovirus 71

(2010) Tom Solomon et al.   LANCET INFECTIOUS DISEASES

Modeling kinetics of a large-scale fed-batch CHO cell culture by Markov chain Monte Carlo method

(2009) Zizhuo Xing et al.   BIOTECHNOLOGY PROGRESS