Monocarboxylate transporter blockage-enabled lactate redistribution reshapes immunosuppressive tumor microenvironment and enhances chemodynamic immunotherapy

Drug-loaded microbubble delivery system to enhance PD-L1 blockade immunotherapy with remodeling immune microenvironment

(2023) Jun Zheng et al.   Biomaterials Research

Manganese-based multifunctional nanoplatform for dual-modal imaging and synergistic therapy of breast cancer

(2022) Chuanda Zhu et al.   Acta Biomaterialia

Combination strategies with PD-1/PD-L1 blockade: current advances and future directions

(2022) Ming Yi et al.   Molecular Cancer

Biphase Co@C core-shell catalysts for efficient Fenton-like catalysis

(2022) Yongsong Ma et al.   JOURNAL OF HAZARDOUS MATERIALS

Coordination-driven Cu-based Fenton-like process for humic acid treatment in wastewater

(2022) Chunying Teng et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Beyond immune checkpoint blockade: emerging immunological strategies

(2021) Shawn P. Kubli et al.   NATURE REVIEWS DRUG DISCOVERY

MnO2-Based Nanomotors with Active Fenton-like Mn2+ Delivery for Enhanced Chemodynamic Therapy

(2021) Juanfeng Ou et al.   ACS Applied Materials & Interfaces

One-pot synthesis of AuPd@FexOy nanoagent with the activable Fe species for enhanced Chemodynamic-photothermal synergetic therapy

(2021) Yanhong Sun et al.   BIOMATERIALS

Double enhancement of immunogenic cell death and antigen presentation for cancer immunotherapy

(2021) Xiang Xiong et al.   Nano Today

Conquering the Hypoxia Limitation for Photodynamic Therapy

(2021) Yilin Wan et al.   ADVANCED MATERIALS

Resistance Mechanisms of Anti-PD1/PDL1 Therapy in Solid Tumors

(2020) Qingyang Lei et al.   Frontiers in Cell and Developmental Biology

Targeted scavenging of extracellular ROS relieves suppressive immunogenic cell death

(2020) Hongzhang Deng et al.   Nature Communications

An ER‐Targeting Iridium(III) Complex That Induces Immunogenic Cell Death in Non‐Small‐Cell Lung Cancer

(2020) Lili Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Na2S2O8 Nanoparticles Trigger Antitumor Immunotherapy through Reactive Oxygen Species Storm and Surge of Tumor Osmolarity

(2020) Yang Liu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Tipping the immunostimulatory and inhibitory DAMP balance to harness immunogenic cell death

(2020) K. Hayashi et al.   Nature Communications

High-Charge Density Polymerized Ionic Networks Boosting High Ionic Conductivity as Quasi-Solid Electrolytes for High-Voltage Batteries

(2019) Xiaolu Tian et al.   ACS Applied Materials & Interfaces

Intra/Extracellular Lactic Acid Exhaustion for Synergistic Metabolic Therapy and Immunotherapy of Tumors

(2019) Fan Gao et al.   ADVANCED MATERIALS

Metal Ion/Tannic Acid Assembly as a Versatile Photothermal Platform in Engineering Multimodal Nanotheranostics for Advanced Applications

(2018) Tao Liu et al.   ACS Nano

Immune Checkpoint PD-1/PD-L1: Is There Life Beyond Antibodies?

(2018) Markella Konstantinidou et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Engineering Multifunctional RNAi Nanomedicine To Concurrently Target Cancer Hallmarks for Combinatorial Therapy

(2018) Yanlan Liu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The cellular metabolic landscape in the tumor milieu regulates the activity of myeloid infiltrates

(2018) Eslam Mohamed et al.   Cellular & Molecular Immunology

Regulation and Function of the PD-L1 Checkpoint

(2018) Chong Sun et al.   IMMUNITY

Chemodynamic Therapy: Tumour Microenvironment-Mediated Fenton and Fenton-like Reaction

(2018) Zhongmin Tang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Chemistry of MRI Contrast Agents: Current Challenges and New Frontiers

(2018) Jessica Wahsner et al.   CHEMICAL REVIEWS

Tumor immunoevasion via acidosis-dependent induction of regulatory tumor-associated macrophages

(2018) Toszka Bohn et al.   NATURE IMMUNOLOGY

LAG-3: a very singular immune checkpoint

(2018) Yuan Lui et al.   NATURE IMMUNOLOGY

Dual Inhibition of the Lactate Transporters MCT1 and MCT4 Is Synthetic Lethal with Metformin due to NAD+ Depletion in Cancer Cells

(2018) Don Benjamin et al.   Cell Reports

Cancer acidity: An ultimate frontier of tumor immune escape and a novel target of immunomodulation

(2017) Veronica Huber et al.   SEMINARS IN CANCER BIOLOGY

Coevolution of T-cell receptors with MHC and non-MHC ligands

(2015) Caitlin D. Castro et al.   IMMUNOLOGICAL REVIEWS

MCT4 Defines a Glycolytic Subtype of Pancreatic Cancer with Poor Prognosis and Unique Metabolic Dependencies

(2014) GuemHee Baek et al.   Cell Reports