Coevolution of T-cell receptors with MHC and non-MHC ligands

T Cell Antigen Receptor Recognition of Antigen-Presenting Molecules

(2015) Jamie Rossjohn et al.   Annual Review of Immunology

Evolution of two prototypic T cell lineages

(2015) Sabyasachi Das et al.   CELLULAR IMMUNOLOGY

Analysis of the reptile CD1 genes: evolutionary implications

(2015) Zhi Yang et al.   IMMUNOGENETICS

High expression of CD26 accurately identifies human bacteria-reactive MR1-restricted MAIT cells

(2015) Prabhat K. Sharma et al.   IMMUNOLOGY

αβ T cell antigen receptor recognition of CD1a presenting self lipid ligands

(2015) Richard W Birkinshaw et al.   NATURE IMMUNOLOGY

Force-dependent transition in the T-cell receptor β-subunit allosterically regulates peptide discrimination and pMHC bond lifetime

(2015) Dibyendu Kumar Das et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

γδT Cells: First Line of Defense and Beyond

(2014) Yueh-hsiu Chien et al.   Annual Review of Immunology

The CD1 size problem: lipid antigens, ligands, and scaffolds

(2014) Dalam Ly et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

The Identification of the Endogenous Ligands of Natural Killer T Cells Reveals the Presence of Mammalian α-Linked Glycosylceramides

(2014) Lisa Kain et al.   IMMUNITY

Unusual evolutionary conservation and further species-specific adaptations of a large family of nonclassical MHC class Ib genes across different degrees of genome ploidy in the amphibian subfamily Xenopodinae

(2014) Eva-Stina Edholm et al.   IMMUNOGENETICS

Genomic V exons from whole genome shotgun data in reptiles

(2014) D. N. Olivieri et al.   IMMUNOGENETICS

MR1-restricted MAIT cells display ligand discrimination and pathogen selectivity through distinct T cell receptor usage

(2014) Marielle C. Gold et al.   JOURNAL OF EXPERIMENTAL MEDICINE

A molecular basis underpinning the T cell receptor heterogeneity of mucosal-associated invariant T cells

(2014) Sidonia B.G. Eckle et al.   JOURNAL OF EXPERIMENTAL MEDICINE

T-cell activation by transitory neo-antigens derived from distinct microbial pathways

(2014) Alexandra J. Corbett et al.   NATURE

Molecular basis of mycobacterial lipid antigen presentation by CD1c and its recognition by    T cells

(2014) S. Roy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

γδ T cell surveillance via CD1 molecules

(2014) Adrienne M. Luoma et al.   TRENDS IN IMMUNOLOGY

The Adaptable Major Histocompatibility Complex (MHC) Fold: Structure and Function of Nonclassical and MHC Class I–Like Molecules

(2013) Erin J. Adams et al.   Annual Review of Immunology

Lck Availability during Thymic Selection Determines the Recognition Specificity of the T Cell Repertoire

(2013) François Van Laethem et al.   CELL

Natural Killer T cell obsession with self-antigens

(2013) Laurent Gapin et al.   CURRENT OPINION IN IMMUNOLOGY

Lipid presentation by human CD1 molecules and the diverse T cell populations that respond to them

(2013) Erin J Adams   CURRENT OPINION IN IMMUNOLOGY

Crystal Structure of Vδ1 T Cell Receptor in Complex with CD1d-Sulfatide Shows MHC-like Recognition of a Self-Lipid by Human γδ T Cells

(2013) Adrienne M. Luoma et al.   IMMUNITY

The equine CD1 gene family is the largest and most diverse yet identified

(2013) Robson G. Dossa et al.   IMMUNOGENETICS

Antigen-loaded MR1 tetramers define T cell receptor heterogeneity in mucosal-associated invariant T cells

(2013) Rangsima Reantragoon et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Cutting Edge: CD1d Restriction and Th1/Th2/Th17 Cytokine Secretion by Human V 3 T Cells

(2013) B. A. Mangan et al.   JOURNAL OF IMMUNOLOGY

MAIT Recognition of a Stimulatory Bacterial Antigen Bound to MR1

(2013) J. Lopez-Sagaseta et al.   JOURNAL OF IMMUNOLOGY

Cutting Edge: CD1a Tetramers and Dextramers Identify Human Lipopeptide-Specific T Cells Ex Vivo

(2013) A. G. Kasmar et al.   JOURNAL OF IMMUNOLOGY

Stimulation of Natural Killer T Cells by Glycolipids

(2013) Brian Anderson et al.   MOLECULES

CD1d-lipid antigen recognition by the γδ TCR

(2013) Adam P Uldrich et al.   NATURE IMMUNOLOGY

The molecular basis for Mucosal-Associated Invariant T cell recognition of MR1 proteins

(2013) J. Lopez-Sagaseta et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nonclassical MHC class I-dependent invariant T cells are evolutionarily conserved and prominent from early development in amphibians

(2013) E.-S. Edholm et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Recognition of vitamin B metabolites by mucosal-associated invariant T cells

(2013) Onisha Patel et al.   Nature Communications

Production of α-Galactosylceramide by a Prominent Member of the Human Gut Microbiota

(2013) Laura C. Wieland Brown et al.   PLOS BIOLOGY

Diversity of γδ T-cell antigens

(2012) Willi K Born et al.   Cellular & Molecular Immunology

The majority of CD1d-sulfatide-specific T cells in human blood use a semiinvariant Vδ1 TCR

(2012) Li Bai et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

γδ T Cells Recognize a Microbial Encoded B Cell Antigen to Initiate a Rapid Antigen-Specific Interleukin-17 Response

(2012) Xun Zeng et al.   IMMUNITY

Structural and comparative analysis of the T cell receptor gamma (TRG) locus in Oryctolagus cuniculus

(2012) Serafina Massari et al.   IMMUNOGENETICS

Exceptionally high conservation of the MHC class I-related gene, MR1, among mammals

(2012) Kentaro Tsukamoto et al.   IMMUNOGENETICS

Molecular basis of lipid antigen presentation by CD1d and recognition by natural killer T cells

(2012) Enrico Girardi et al.   IMMUNOLOGICAL REVIEWS

The structural basis of αβ T-lineage immune recognition: TCR docking topologies, mechanotransduction, and co-receptor function

(2012) Jia-huai Wang et al.   IMMUNOLOGICAL REVIEWS

The bovine CD1D gene has an unusual gene structure and is expressed but cannot present  -galactosylceramide with a C26 fatty acid

(2012) T. K. A. Nguyen et al.   INTERNATIONAL IMMUNOLOGY

A Second TCR  Locus in Galliformes Uses Antibody-like V Domains: Insight into the Evolution of TCR  and TCR  Genes in Tetrapods

(2012) Z. E. Parra et al.   JOURNAL OF IMMUNOLOGY

A Model for the Evolution of the Mammalian T-cell Receptor  /  and   Loci Based on Evidence from the Duckbill Platypus

(2012) Z. E. Parra et al.   MOLECULAR BIOLOGY AND EVOLUTION

Recognition of CD1d-sulfatide mediated by a type II natural killer T cell antigen receptor

(2012) Onisha Patel et al.   NATURE IMMUNOLOGY

Type II natural killer T cells use features of both innate-like and conventional T cells to recognize sulfatide self antigens

(2012) Enrico Girardi et al.   NATURE IMMUNOLOGY

Crystal Structures of Bovine CD1d Reveal Altered αGalCer Presentation and a Restricted A’ Pocket Unable to Bind Long-Chain Glycolipids

(2012) Jing Wang et al.   PLoS One

Novel insights into lipid antigen presentation

(2012) Gennaro De Libero et al.   TRENDS IN IMMUNOLOGY

Evolutionarily Conserved Features Contribute to αβ T Cell Receptor Specificity

(2011) James P. Scott-Browne et al.   IMMUNITY

The Immutable Recognition of CD1d

(2011) Erin J. Adams et al.   IMMUNITY

αβ T Cell Receptors that Do Not Undergo Major Histocompatibility Complex-Specific Thymic Selection Possess Antibody-like Recognition Specificities

(2011) Anastasia N. Tikhonova et al.   IMMUNITY

T cell receptor signal strength in Tregand iNKT cell development demonstrated by a novel fluorescent reporter mouse

(2011) Amy E. Moran et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Platypus TCR μ Provides Insight into the Origins and Evolution of a Uniquely Mammalian TCR Locus

(2011) Xinxin Wang et al.   JOURNAL OF IMMUNOLOGY

Cutting Edge: Structural Basis for the Recognition of  -Linked Glycolipid Antigens by Invariant NKT Cells

(2011) E. D. Yu et al.   JOURNAL OF IMMUNOLOGY

Cardiolipin Binds to CD1d and Stimulates CD1d-Restricted    T Cells in the Normal Murine Repertoire

(2011) M. Dieude et al.   JOURNAL OF IMMUNOLOGY

Recognition of β-linked self glycolipids mediated by natural killer T cell antigen receptors

(2011) Daniel G Pellicci et al.   NATURE IMMUNOLOGY

Evolution of the V, D, and J gene segments used in the primate    T-cell receptor reveals a dichotomy of conservation and diversity

(2011) A. R. Kazen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural reorganization of the antigen-binding groove of human CD1b for presentation of mycobacterial sulfoglycolipids

(2011) L. F. Garcia-Alles et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Crystal structure of human CD1e reveals a groove suited for lipid-exchange processes

(2011) Luis F. Garcia-Alles et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fine tuning by human CD1e of lipid-specific immune responses

(2011) F. Facciotti et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fecundity in adult Haemonchus contortus parasites is correlated with abomasal tissue eosinophils and γδ T cells in resistant Canaria Hair Breed sheep

(2011) Jorge F. González et al.   VETERINARY PARASITOLOGY

Recent advances in processing and presentation of CD1 bound lipid antigens

(2010) Mariolina Salio et al.   CURRENT OPINION IN IMMUNOLOGY

The dynamic TCRδ: TCRδ chains in the amphibian Xenopus tropicalis utilize antibody-like V genes

(2010) Zuly E. Parra et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

High-frequency and adaptive-like dynamics of human CD1 self-reactive T cells

(2010) Claudia de Lalla et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

The 2.5 Å Structure of CD1c in Complex with a Mycobacterial Lipid Reveals an Open Groove Ideally Suited for Diverse Antigen Presentation

(2010) Louise Scharf et al.   IMMUNITY

The Vα14 invariant natural killer T cell TCR forces microbial glycolipids and CD1d into a conserved binding mode

(2010) Yali Li et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Crystal Structure of Bovine CD1b3 with Endogenously Bound Ligands

(2010) E. Girardi et al.   JOURNAL OF IMMUNOLOGY

Remarkable Conservation of Distinct Nonclassical MHC Class I Lineages in Divergent Amphibian Species

(2010) A. Goyos et al.   JOURNAL OF IMMUNOLOGY

Structural Basis for Lipid-Antigen Recognition in Avian Immunity

(2010) Hay Dvir et al.   JOURNAL OF IMMUNOLOGY

Evolutionarily Conserved TCR Binding Sites, Identification of T Cells in Primary Lymphoid Tissues, and Surprising Trans-Rearrangements in Nurse Shark

(2010) M. F. Criscitiello et al.   JOURNAL OF IMMUNOLOGY

Conservation of mucosal associated invariant T (MAIT) cells and the MR1 restriction element in ruminants, and abundance of MAIT cells in spleen

(2010) Nick Goldfinch et al.   VETERINARY RESEARCH

Structure of a Classical MHC Class I Molecule That Binds “Non-Classical” Ligands

(2010) Chee Seng Hee et al.   PLOS BIOLOGY

Multiple tissue-specific isoforms of sulfatide activate CD1d-restricted type II NKT cells

(2009) Maria Blomqvist et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

CD1-restricted adaptive immune responses toMycobacteriain human group 1 CD1 transgenic mice

(2009) Kyrie Felio et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The deduced structure of the T cell receptor gamma locus in Canis lupus familiaris

(2009) S. Massari et al.   MOLECULAR IMMUNOLOGY

Functional CD1d and/or NKT cell invariant chain transcript in horse, pig, African elephant and guinea pig, but not in ruminants

(2009) Frank A. Looringh van Beeck et al.   MOLECULAR IMMUNOLOGY

Germline-encoded amino acids in the αβ T-cell receptor control thymic selection

(2009) James P. Scott-Browne et al.   NATURE

The molecular basis of TCR germline bias for MHC is surprisingly simple

(2009) K Christopher Garcia et al.   NATURE IMMUNOLOGY

MR1 antigen presentation to mucosal-associated invariant T cells was highly conserved in evolution

(2009) S. Huang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Characterization of arrangement and expression of the T cell receptor   locus in the sandbar shark

(2009) H. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lipid binding orientation within CD1d affects recognition of Borrelia burgorferi antigens by NKT cells

(2009) J. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of canine natural CD3-positive T cells expressing an invariant T-cell receptor alpha chain

(2009) Nobutaka Yasuda et al.   VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY

Stepwise Development of MAIT Cells in Mouse and Human

(2009) Emmanuel Martin et al.   PLOS BIOLOGY

Evolutionarily Conserved Amino Acids That Control TCR-MHC Interaction

(2008) Philippa Marrack et al.   Annual Review of Immunology

Comparative genomic analysis and evolution of the T cell receptor loci in the opossum Monodelphis domestica.

(2008) Zuly E Parra et al.   BMC GENOMICS

TCR-MHC docking orientation: natural selection, or thymic selection?

(2008) Edward J. Collins et al.   IMMUNOLOGIC RESEARCH

A minimal binding footprint on CD1d-glycolipid is a basis for selection of the unique human NKT TCR

(2008) Kwok S. Wun et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Crystal Structures of Mouse CD1d-iGb3 Complex and its Cognate Vα14 T Cell Receptor Suggest a Model for Dual Recognition of Foreign and Self Glycolipids

(2008) Dirk M. Zajonc et al.   JOURNAL OF MOLECULAR BIOLOGY

Functional adaptive diversity of the Atlantic salmon T-cell receptor gamma locus

(2008) Ryosuke Yazawa et al.   MOLECULAR IMMUNOLOGY

The crystal structure of avian CD1 reveals a smaller, more primordial antigen-binding pocket compared to mammalian CD1

(2008) D. M. Zajonc et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA