Targeted scavenging of extracellular ROS relieves suppressive immunogenic cell death

Synthetic Immunogenic Cell Death Mediated by Intracellular Delivery of STING Agonist Nanoshells Enhances Anticancer Chemo-immunotherapy

(2020) Saborni Chattopadhyay et al.   NANO LETTERS

Collagen-binding IL-12 enhances tumour inflammation and drives the complete remission of established immunologically cold mouse tumours

(2020) Aslan Mansurov et al.   Nature Biomedical Engineering

Tumor Microenvironment-Activatable Prodrug Vesicles for Nanoenabled Cancer Chemoimmunotherapy Combining Immunogenic Cell Death Induction and CD47 Blockade

(2019) Fangyuan Zhou et al.   ADVANCED MATERIALS

Therapeutic targeting of trained immunity

(2019) Willem J. M. Mulder et al.   NATURE REVIEWS DRUG DISCOVERY

Computationally designed antibody–drug conjugates self-assembled via affinity ligands

(2019) Nimish Gupta et al.   Nature Biomedical Engineering

In situ formed reactive oxygen species–responsive scaffold with gemcitabine and checkpoint inhibitor for combination therapy

(2018) Chao Wang et al.   Science Translational Medicine

Rapid measurement of inhibitor binding kinetics by isothermal titration calorimetry

(2018) Justin M. Di Trani et al.   Nature Communications

Low-dose X-ray radiotherapy–radiodynamic therapy via nanoscale metal–organic frameworks enhances checkpoint blockade immunotherapy

(2018) Kuangda Lu et al.   Nature Biomedical Engineering

Immunomodulating Nanomedicine for Cancer Therapy

(2018) Zhigang Liu et al.   NANO LETTERS

ROS-targeting of melanoma cells provides immuno-protection against tumor growth

(2018) Sander Bekeschus   FREE RADICAL BIOLOGY AND MEDICINE

Danger signals: Chemotherapy enhancers?

(2017) Thaiz Rivera Vargas et al.   IMMUNOLOGICAL REVIEWS

Berunda Polypeptides: Multi-Headed Fusion Proteins Promote Subcutaneous Administration of Rapamycin to Breast Cancer In Vivo

(2017) Jugal P. Dhandhukia et al.   Theranostics

Autophagy, Inflammation, and Immunity: A Troika Governing Cancer and Its Treatment

(2016) Zhenyu Zhong et al.   CELL

The EGFR-specific antibody cetuximab combined with chemotherapy triggers immunogenic cell death

(2016) Chiara Pozzi et al.   NATURE MEDICINE

Integration and global analysis of isothermal titration calorimetry data for studying macromolecular interactions

(2016) Chad A Brautigam et al.   Nature Protocols

Programmed Death-1 Controls T Cell Survival by Regulating Oxidative Metabolism

(2015) Victor Tkachev et al.   JOURNAL OF IMMUNOLOGY

In situ vaccination by radiotherapy to improve responses to anti-CTLA-4 treatment

(2015) Claire Vanpouille-Box et al.   VACCINE

Danger signalling during cancer cell death: origins, plasticity and regulation

(2013) A D Garg et al.   CELL DEATH AND DIFFERENTIATION

Subsets of human type 2 macrophages show differential capacity to produce reactive oxygen species

(2013) Marina D. Kraaij et al.   CELLULAR IMMUNOLOGY

Physiological Roles of Mitochondrial Reactive Oxygen Species

(2012) Laura A. Sena et al.   MOLECULAR CELL

The secret ally: immunostimulation by anticancer drugs

(2012) Lorenzo Galluzzi et al.   NATURE REVIEWS DRUG DISCOVERY

Colocalization of Inflammatory Response with B7-H1 Expression in Human Melanocytic Lesions Supports an Adaptive Resistance Mechanism of Immune Escape

(2012) J. M. Taube et al.   Science Translational Medicine

Immunogenic Tumor Cell Death for Optimal Anticancer Therapy: The Calreticulin Exposure Pathway

(2010) L. Zitvogel et al.   CLINICAL CANCER RESEARCH

Reactive oxygen species in cancer

(2010) Geou-Yarh Liou et al.   FREE RADICAL RESEARCH

Reactive Oxygen Species Level Defines Two Functionally Distinctive Stages of Inflammatory Dendritic Cell Development from Mouse Bone Marrow

(2010) K.-C. Sheng et al.   JOURNAL OF IMMUNOLOGY

High-Affinity Peptide-Based Collagen Targeting Using Synthetic Phage Mimics: From Phage Display to Dendrimer Display

(2009) Brett A. Helms et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach?

(2009) Dunyaporn Trachootham et al.   NATURE REVIEWS DRUG DISCOVERY

Induction of Immunological Tolerance by Apoptotic Cells Requires Caspase-Dependent Oxidation of High-Mobility Group Box-1 Protein

(2008) Hirotaka Kazama et al.   IMMUNITY