Overlap in synaptic neurological condition susceptibility pathways and the neural pannexin 1 interactome revealed by bioinformatics analyses

Pre-symptomatic synaptic dysfunction and longitudinal decay of hippocampal synaptic function in APPPS1 mouse model of Alzheimer’s disease is sex-independent

(2023) Sha Sha et al.   BRAIN RESEARCH BULLETIN

Local genetic correlations exist among neurodegenerative and neuropsychiatric diseases

(2023) Regina H. Reynolds et al.   npj Parkinsons Disease

De novo GRIN2A variants associated with epilepsy and autism and literature review

(2022) Giuseppe Donato Mangano et al.   EPILEPSY & BEHAVIOR

Mutation Burden Analysis of Six Common Mental Disorders in African Americans by Whole Genome Sequencing

(2022) Yichuan Liu et al.   HUMAN MOLECULAR GENETICS

Rare coding variants in ten genes confer substantial risk for schizophrenia

(2022) Tarjinder Singh et al.   NATURE

Identification of ultra-rare genetic variants in pediatric acute onset neuropsychiatric syndrome (PANS) by exome and whole genome sequencing

(2022) Rosario Trifiletti et al.   Scientific Reports

Rapid macropinocytic transfer of α-synuclein to lysosomes

(2022) Armin Bayati et al.   Cell Reports

Prioritizing Suggestive Candidate Genes in Migraine: An Opinion

(2022) Simona Denise Frederiksen   Frontiers in Neurology

Genenames.org: the HGNC resources in 2023

(2022) Ruth L Seal et al.   NUCLEIC ACIDS RESEARCH

Multi‐Omics Studies in Historically Excluded Populations: The Road to Equity

(2022) Guang Yang et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Early TNF-Dependent Regulation of Excitatory and Inhibitory Synapses on Striatal Direct Pathway Medium Spiny Neurons in the YAC128 Mouse Model of Huntington's Disease

(2022) Julien Chambon et al.   JOURNAL OF NEUROSCIENCE

The STRING database in 2023: protein–protein association networks and functional enrichment analyses for any sequenced genome of interest

(2022) Damian Szklarczyk et al.   NUCLEIC ACIDS RESEARCH

The NHGRI-EBI GWAS Catalog: knowledgebase and deposition resource

(2022) Elliot Sollis et al.   NUCLEIC ACIDS RESEARCH

Shared mechanisms of neural circuit disruption in tuberous sclerosis across lifespan: Bridging neurodevelopmental and neurodegenerative pathology

(2022) Karen Litwa   Frontiers in Genetics

The Long-Term Pannexin 1 Ablation Produces Structural and Functional Modifications in Hippocampal Neurons

(2022) Carolina Flores-Muñoz et al.   Cells

Global, regional, and national burden and attributable risk factors of neurological disorders: The Global Burden of Disease study 1990–2019

(2022) Chenyu Ding et al.   Frontiers in Public Health

Pannexin-1 Channels as Mediators of Neuroinflammation

(2021) Joon Ho Seo et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Protein-protein interactions at the NMDA receptor complex: From synaptic retention to synaptonuclear protein messengers

(2021) Fabrizio Gardoni et al.   NEUROPHARMACOLOGY

Purinergic signaling in nervous system health and disease: Focus on pannexin 1

(2021) Juan C. Sanchez-Arias et al.   PHARMACOLOGY & THERAPEUTICS

Haploinsufficiency of the schizophrenia and autism risk gene Cyfip1 causes abnormal postnatal hippocampal neurogenesis through microglial and Arp2/3 mediated actin dependent mechanisms

(2021) Niels Haan et al.   Translational Psychiatry

FGF, Mechanism of Action, Role in Parkinson’s Disease, and Therapeutics

(2021) Yiqiu Liu et al.   Frontiers in Pharmacology

PANTHER : Making genome‐scale phylogenetics accessible to all

(2021) Paul D. Thomas et al.   PROTEIN SCIENCE

Overlapping Genetic Architecture Between Schizophrenia and Neurodegenerative Disorders

(2021) Chunyu Li et al.   Frontiers in Cell and Developmental Biology

CRMP 2 mediates Sema3F‐dependent axon pruning and dendritic spine remodeling

(2020) Jakub Ziak et al.   EMBO REPORTS

Twenty Years of SynGAP Research: From Synapses to Cognition

(2020) Timothy R. Gamache et al.   JOURNAL OF NEUROSCIENCE

An atlas of the protein-coding genes in the human, pig, and mouse brain

(2020) Evelina Sjöstedt et al.   SCIENCE

Endothelial Pannexin 1 Channels Control Inflammation by Regulating Intracellular Calcium

(2020) Yang Yang et al.   JOURNAL OF IMMUNOLOGY

Pannexin‐1 in the CNS: emerging concepts in health and disease

(2020) Albert K. Yeung et al.   JOURNAL OF NEUROCHEMISTRY

Acute Pannexin 1 Blockade Mitigates Early Synaptic Plasticity Defects in a Mouse Model of Alzheimer’s Disease

(2020) Carolina Flores-Muñoz et al.   Frontiers in Cellular Neuroscience

Consideration of Pannexin 1 channels in COVID-19 pathology and treatment

(2020) Leigh Anne Swayne et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Parkinson's: A Disease of Aberrant Vesicle Trafficking

(2020) Pawan Kishor Singh et al.   Annual Review of Cell and Developmental Biology

Pannexin 1 regulates dendritic protrusion dynamics in immature cortical neurons

(2020) Juan C. Sanchez-Arias et al.   eNeuro

PANX1 in inflammation heats up: New mechanistic insights with implications for injury and infection

(2020) Juan C. Sanchez Arias et al.   CELL CALCIUM

Signalling Pathways Implicated in Alzheimer′s Disease Neurodegeneration in Individuals with and without Down Syndrome

(2020) Carmen Martínez-Cué et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Genetic architecture of Alzheimer's disease

(2020) Sarah M. Neuner et al.   NEUROBIOLOGY OF DISEASE

PANTHER version 16: a revised family classification, tree-based classification tool, enhancer regions and extensive API

(2020) Huaiyu Mi et al.   NUCLEIC ACIDS RESEARCH

The Gene Ontology resource: enriching a GOld mine

(2020) et al.   NUCLEIC ACIDS RESEARCH

Mouse Genome Database (MGD): Knowledgebase for mouse–human comparative biology

(2020) Judith A Blake et al.   NUCLEIC ACIDS RESEARCH

The STRING database in 2021: customizable protein–protein networks, and functional characterization of user-uploaded gene/measurement sets

(2020) Damian Szklarczyk et al.   NUCLEIC ACIDS RESEARCH

KALRN: A central regulator of synaptic function and synaptopathies

(2020) Euan Parnell et al.   GENE

Protocol Update for large-scale genome and gene function analysis with the PANTHER classification system (v.14.0)

(2019) Huaiyu Mi et al.   Nature Protocols

Synapse Formation: From Cellular and Molecular Mechanisms to Neurodevelopmental and Neurodegenerative Disorders

(2019) Shadab Batool et al.   JOURNAL OF NEUROPHYSIOLOGY

Plasticity of dendritic spines: Molecular function and dysfunction in neurodevelopmental disorders

(2019) Jun Nishiyama   PSYCHIATRY AND CLINICAL NEUROSCIENCES

gwasrapidd: an R package to query, download and wrangle GWAS catalog data

(2019) Ramiro Magno et al.   BIOINFORMATICS

Genetic Causes and Modifiers of Autism Spectrum Disorder

(2019) Lauren Rylaarsdam et al.   Frontiers in Cellular Neuroscience

VariCarta: A Comprehensive Database of Harmonized Genomic Variants Found in Autism Spectrum Disorder Sequencing Studies

(2019) Manuel Belmadani et al.   Autism Research

GRIN2D/GluN2D NMDA receptor: Unique features and its contribution to pediatric developmental and epileptic encephalopathy

(2019) Chad R. Camp et al.   EUROPEAN JOURNAL OF PAEDIATRIC NEUROLOGY

Transcriptional and post-translational regulation of pannexins

(2018) Andrew K.J. Boyce et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Species-conserved SYNGAP1 phenotypes associated with neurodevelopmental disorders

(2018) Murat Kilinc et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Dendritic structural plasticity and neuropsychiatric disease

(2018) Marc P. Forrest et al.   NATURE REVIEWS NEUROSCIENCE

Pannexin-1 channel dysfunction in the medial prefrontal cortex mediates depressive-like behaviors induced by chronic social defeat stress and administration of mefloquine in mice

(2018) Ming Ni et al.   NEUROPHARMACOLOGY

Analysis of shared heritability in common disorders of the brain

(2018) et al.   SCIENCE

Probenecid Disrupts a Novel Pannexin 1-Collapsin Response Mediator Protein 2 Interaction and Increases Microtubule Stability

(2018) Xiaoxue Xu et al.   Frontiers in Cellular Neuroscience

Rare loss of function mutations in N-methyl-d-aspartate glutamate receptors and their contributions to schizophrenia susceptibility

(2018) Yanjie Yu et al.   Translational Psychiatry

Lack of Pannexin 1 Alters Synaptic GluN2 Subunit Composition and Spatial Reversal Learning in Mice

(2018) Ivana Gajardo et al.   Frontiers in Molecular Neuroscience

CRMP2 Hyperphosphorylation is Characteristic of Alzheimer's Disease and not a Feature Common to Other Neurodegenerative Diseases

(2018) Ritchie Williamson et al.   JOURNAL OF ALZHEIMERS DISEASE

OUP accepted manuscript

(2018)   SCHIZOPHRENIA BULLETIN

Synaptic dysfunction in neurodegenerative and neurodevelopmental diseases: an overview of induced pluripotent stem-cell-based disease models

(2018) Era Taoufik et al.   Open Biology

Mouse Genome Database (MGD) 2019

(2018) Carol J Bult et al.   NUCLEIC ACIDS RESEARCH

STRING v11: protein–protein association networks with increased coverage, supporting functional discovery in genome-wide experimental datasets

(2018) Damian Szklarczyk et al.   NUCLEIC ACIDS RESEARCH

The NHGRI-EBI GWAS Catalog of published genome-wide association studies, targeted arrays and summary statistics 2019

(2018) Annalisa Buniello et al.   NUCLEIC ACIDS RESEARCH

Genetics implicate common mechanisms in autism and schizophrenia: synaptic activity and immunity

(2017) Xiaoming Liu et al.   JOURNAL OF MEDICAL GENETICS

Loss and remodeling of striatal dendritic spines in Parkinson’s disease: from homeostasis to maladaptive plasticity?

(2017) Rosa M. Villalba et al.   JOURNAL OF NEURAL TRANSMISSION

ASD and schizophrenia show distinct developmental profiles in common genetic overlap with population-based social communication difficulties

(2017) B St Pourcain et al.   MOLECULAR PSYCHIATRY

Regulation of pannexin channels in the central nervous system by Src family kinases

(2017) Alexander W. Lohman et al.   NEUROSCIENCE LETTERS

Genetic Determinants of Parkinson's Disease: Can They Help to Stratify the Patients Based on the Underlying Molecular Defect?

(2017) Sara Redenšek et al.   Frontiers in Aging Neuroscience

Dendritic Spine Pathology in Neurodegenerative Diseases

(2016) Jochen Herms et al.   Annual Review of Pathology-Mechanisms of Disease

Back to the tubule: microtubule dynamics in Parkinson’s disease

(2016) Laura Pellegrini et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Collapsin Response Mediator Protein-2 (CRMP2) is a Plausible Etiological Factor and Potential Therapeutic Target in Alzheimer’s Disease: Comparison and Contrast with Microtubule-Associated Protein Tau

(2016) Kenneth Hensley et al.   JOURNAL OF ALZHEIMERS DISEASE

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(2016) E. F. Spence et al.   JOURNAL OF NEUROSCIENCE

Metabotropic NMDA receptor signaling couples Src family kinases to pannexin-1 during excitotoxicity

(2016) Nicholas L Weilinger et al.   NATURE NEUROSCIENCE

The STRING database in 2017: quality-controlled protein–protein association networks, made broadly accessible

(2016) Damian Szklarczyk et al.   NUCLEIC ACIDS RESEARCH

A Subset of Autism-Associated Genes Regulate the Structural Stability of Neurons

(2016) Yu-Chih Lin et al.   Frontiers in Cellular Neuroscience

Brain-specific Crmp2 deletion leads to neuronal development deficits and behavioural impairments in mice

(2016) Hongsheng Zhang et al.   Nature Communications

ATP stimulates pannexin 1 internalization to endosomal compartments

(2015) A. K. J. Boyce et al.   BIOCHEMICAL JOURNAL

Changes in Dpysl2 expression are associated with prenatally stressed rat offspring and susceptibility to schizophrenia in humans

(2015) HWAYOUNG LEE et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Molecular regulation of dendritic spine dynamics and their potential impact on synaptic plasticity and neurological diseases

(2015) Panchanan Maiti et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Dendritic spine dysgenesis in autism related disorders

(2015) Mary Phillips et al.   NEUROSCIENCE LETTERS

How Schizophrenia Develops: Cognitive and Brain Mechanisms Underlying Onset of Psychosis

(2015) Tyrone D. Cannon   TRENDS IN COGNITIVE SCIENCES

Giant ankyrin-G stabilizes somatodendritic GABAergic synapses through opposing endocytosis of GABAAreceptors

(2015) Wei Chou Tseng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Psychiatric Risk Factor ANK3/Ankyrin-G Nanodomains Regulate the Structure and Function of Glutamatergic Synapses

(2014) Katharine R. Smith et al.   NEURON

Economic Burden of Childhood Autism Spectrum Disorders

(2014) T. A. Lavelle et al.   PEDIATRICS

Pannexin 1 regulates bidirectional hippocampal synaptic plasticity in adult mice

(2014) Alvaro O. Ardiles et al.   Frontiers in Cellular Neuroscience

Functional Variants in DPYSL2 Sequence Increase Risk of Schizophrenia and Suggest a Link to mTOR Signaling

(2014) Yaping Liu et al.   G3-Genes Genomes Genetics

Panx1 regulates neural stem and progenitor cell behaviours associated with cytoskeletal dynamics and interacts with multiple cytoskeletal elements

(2013) Leigh E Wicki-Stordeur et al.   Cell Communication and Signaling

Disruption of Arp2/3 Results in Asymmetric Structural Plasticity of Dendritic Spines and Progressive Synaptic and Behavioral Abnormalities

(2013) I. H. Kim et al.   JOURNAL OF NEUROSCIENCE

Activity-dependent neuronal signalling and autism spectrum disorder

(2013) Daniel H. Ebert et al.   NATURE

Autism-specific maternal autoantibodies recognize critical proteins in developing brain

(2013) D Braunschweig et al.   Translational Psychiatry

Genetic insights in Alzheimer's disease

(2012) Karolien Bettens et al.   LANCET NEUROLOGY

Pannexin1 Stabilizes Synaptic Plasticity and Is Needed for Learning

(2012) Nora Prochnow et al.   PLoS One

Loci nominally associated with autism from genome-wide analysis show enrichment of brain expression quantitative trait loci but not lymphoblastoid cell line expression quantitative trait loci

(2012) Lea K Davis et al.   Molecular Autism

Metaplasticity gated through differential regulation of GluN2A versus GluN2B receptors by Src family kinases

(2011) Kai Yang et al.   EMBO JOURNAL

Dendritic spine pathology in neuropsychiatric disorders

(2011) Peter Penzes et al.   NATURE NEUROSCIENCE

Modeling sample variables with an Experimental Factor Ontology

(2010) James Malone et al.   BIOINFORMATICS

Flotillin-1 promotes formation of glutamatergic synapses in hippocampal neurons

(2010) Catherine Croft Swanwick et al.   Developmental Neurobiology

Interaction of dopamine D1 receptor with N-ethylmaleimide-sensitive factor is important for the membrane localization of the receptor

(2010) Sheng Chen et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Towards a knowledge-based Human Protein Atlas

(2010) Mathias Uhlen et al.   NATURE BIOTECHNOLOGY

Early Increase in Extrasynaptic NMDA Receptor Signaling and Expression Contributes to Phenotype Onset in Huntington's Disease Mice

(2010) Austen J. Milnerwood et al.   NEURON

Early synaptic pathophysiology in neurodegeneration: insights from Huntington's disease

(2010) Austen J. Milnerwood et al.   TRENDS IN NEUROSCIENCES

bioDBnet: the biological database network

(2009) Uma Mudunuri et al.   BIOINFORMATICS

Differentiation of mouse Neuro 2A cells into dopamine neurons

(2009) Roger G. Tremblay et al.   JOURNAL OF NEUROSCIENCE METHODS

Accurate and Sensitive Peptide Identification with Mascot Percolator

(2009) Markus Brosch et al.   JOURNAL OF PROTEOME RESEARCH

Cytoskeletal pathologies of Alzheimer disease

(2009) James R. Bamburg et al.   CELL MOTILITY AND THE CYTOSKELETON

CellDesigner 3.5: A Versatile Modeling Tool for Biochemical Networks

(2008) A. Funahashi et al.   PROCEEDINGS OF THE IEEE