Loss and remodeling of striatal dendritic spines in Parkinson’s disease: from homeostasis to maladaptive plasticity?

Striatal Neurons Expressing D1 and D2 Receptors are Morphologically Distinct and Differently Affected by Dopamine Denervation in Mice

(2017) D. Gagnon et al.   Scientific Reports

L-DOPA Oppositely Regulates Synaptic Strength and Spine Morphology in D1 and D2 Striatal Projection Neurons in Dyskinesia

(2016) Luz M Suarez et al.   CEREBRAL CORTEX

Role of astrocyte-synapse interactions in CNS disorders

(2016) Elena Blanco-Suárez et al.   JOURNAL OF PHYSIOLOGY-LONDON

Pathway-Specific Remodeling of Thalamostriatal Synapses in Parkinsonian Mice

(2016) Philip R.L. Parker et al.   NEURON

L-DOPA Reverses the Increased Free Amino Acids Tissue Levels Induced by Dopamine Depletion and Rises GABA and Tyrosine in the Striatum

(2016) Oscar Solís et al.   NEUROTOXICITY RESEARCH

Human striatal recordings reveal abnormal discharge of projection neurons in Parkinson’s disease

(2016) Arun Singh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Subthalamic, not striatal, activity correlates with basal ganglia downstream activity in normal and parkinsonian monkeys

(2016) Marc Deffains et al.   eLife

Cholinergic interneurons in the dorsal and ventral striatum: anatomical and functional considerations in normal and diseased conditions

(2015) Kalynda K. Gonzales et al.   Annals of the New York Academy of Sciences

Activation of DREAM (Downstream Regulatory Element Antagonistic Modulator), a Calcium-Binding Protein, Reduces L-DOPA-Induced Dyskinesias in Mice

(2015) Irene Ruiz-DeDiego et al.   BIOLOGICAL PSYCHIATRY

The D3 dopamine receptor: From structural interactions to function

(2015) Chiara Fiorentini et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Morphological plasticity of astroglia: Understanding synaptic microenvironment

(2015) Janosch P. Heller et al.   GLIA

Three-dimensional immersive virtual reality for studying cellular compartments in 3D models from EM preparations of neural tissues

(2015) Corrado Calì et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Dopamine regulates distinctively the activity patterns of striatal output neurons in advanced parkinsonian primates

(2015) Arun Singh et al.   JOURNAL OF NEUROPHYSIOLOGY

Interaction between hyperdirect and indirect basal ganglia pathways

(2015) Stella M. Papa et al.   MOVEMENT DISORDERS

Dopaminergic regulation of olfactory type G-protein α subunit expression in the striatum

(2015) I. Ruiz-DeDiego et al.   MOVEMENT DISORDERS

Zooming in on the small: The plasticity of striatal dendritic spines inl-DOPA-Induced dyskinesia

(2015) Tim Fieblinger et al.   MOVEMENT DISORDERS

Nitric oxide synthase inhibition decreases l-DOPA-induced dyskinesia and the expression of striatal molecular markers in Pitx3−/− aphakia mice

(2015) Oscar Solís et al.   NEUROBIOLOGY OF DISEASE

Circuit-specific signaling in astrocyte-neuron networks in basal ganglia pathways

(2015) R. Martin et al.   SCIENCE

Morphological changes of glutamatergic synapses in animal models of Parkinson’s disease

(2015) Rosa M. Villalba et al.   Frontiers in Neuroanatomy

The Thorny Problem of Dyskinesias: Dendritic Spines, Synaptic Plasticity, and Striatal Dysfunction

(2014) Ariel Y. Deutch   BIOLOGICAL PSYCHIATRY

The cortico-pallidal projection: An additional route for cortical regulation of the basal ganglia circuitry

(2014) Yoland Smith et al.   MOVEMENT DISORDERS

Cell type-specific plasticity of striatal projection neurons in parkinsonism and L-DOPA-induced dyskinesia

(2014) Tim Fieblinger et al.   Nature Communications

Astrocytosis in parkinsonism: considering tripartite striatal synapses in physiopathology?

(2014) Giselle Charron et al.   Frontiers in Aging Neuroscience

L-DOPA Treatment Selectively Restores Spine Density in Dopamine Receptor D2–Expressing Projection Neurons in Dyskinetic Mice

(2013) Luz M. Suárez et al.   BIOLOGICAL PSYCHIATRY

Neuronal loss in the caudal intralaminar thalamic nuclei in a primate model of Parkinson’s disease

(2013) R. M. Villalba et al.   Brain Structure & Function

Convergence of cortical and thalamic input to direct and indirect pathway medium spiny neurons in the striatum

(2013) Icnelia Huerta-Ocampo et al.   Brain Structure & Function

Modeling Parkinson's disease in monkeys for translational studies, a critical analysis

(2013) Lisa F. Potts et al.   EXPERIMENTAL NEUROLOGY

Aberrant Restoration of Spines and their Synapses in L-DOPA-Induced Dyskinesia: Involvement of Corticostriatal but Not Thalamostriatal Synapses

(2013) Y. Zhang et al.   JOURNAL OF NEUROSCIENCE

The Organization of Prefrontal-Subthalamic Inputs in Primates Provides an Anatomical Substrate for Both Functional Specificity and Integration: Implications for Basal Ganglia Models and Deep Brain Stimulation

(2013) W. I. A. Haynes et al.   JOURNAL OF NEUROSCIENCE

Treadmill exercise reverses dendritic spine loss in direct and indirect striatal medium spiny neurons in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) mouse model of Parkinson's disease

(2013) William A. Toy et al.   NEUROBIOLOGY OF DISEASE

Differential striatal spine pathology in Parkinson’s disease and cocaine addiction: A key role of dopamine?

(2013) R.M. Villalba et al.   NEUROSCIENCE

Functional Neuroanatomy of the Basal Ganglia

(2013) J. L. Lanciego et al.   Cold Spring Harbor Perspectives in Medicine

The effects of nigrostriatal dopamine depletion on the thalamic parafascicular nucleus

(2012) Sheila V. Kusnoor et al.   BRAIN RESEARCH

Changing Views of Basal Ganglia Circuits and Circuit Disorders

(2012) Mahlon DeLong et al.   CLINICAL EEG AND NEUROSCIENCE

Confocal laser scanning microscopy and ultrastructural study of VGLUT2 thalamic input to striatal projection neurons in rats

(2012) Wanlong Lei et al.   JOURNAL OF COMPARATIVE NEUROLOGY

L-DOPA-induced increase in TH-immunoreactive striatal neurons in parkinsonian mice: Insights into regulation and function

(2012) Isabel Espadas et al.   NEUROBIOLOGY OF DISEASE

Distribution of GABAergic Interneurons and Dopaminergic Cells in the Functional Territories of the Human Striatum

(2012) Javier Bernácer et al.   PLoS One

Modulation of Striatal Projection Systems by Dopamine

(2011) Charles R. Gerfen et al.   Annual Review of Neuroscience

Dendritic spine pathology in neuropsychiatric disorders

(2011) Peter Penzes et al.   NATURE NEUROSCIENCE

Heterogeneity and Diversity of Striatal GABAergic Interneurons

(2011) James M. Tepper et al.   Frontiers in Neuroanatomy

Extrastriatal dopaminergic circuits of the basal ganglia

(2011) Karen S. Rommelfanger   Frontiers in Neuroanatomy

Striatal Signaling in L-DOPA-Induced Dyskinesia: Common Mechanisms with Drug Abuse and Long Term Memory Involving D1 Dopamine Receptor Stimulation

(2011) Mario Gustavo Murer et al.   Frontiers in Neuroanatomy

Morphology and dynamics of perisynaptic glia

(2010) Andreas Reichenbach et al.   BRAIN RESEARCH REVIEWS

Cortical Regulation of Striatal Medium Spiny Neuron Dendritic Remodeling in Parkinsonism: Modulation of Glutamate Release Reverses Dopamine Depletion–Induced Dendritic Spine Loss

(2010) Bonnie G. Garcia et al.   CEREBRAL CORTEX

Impact of dendritic spine preservation in medium spiny neurons on dopamine graft efficacy and the expression of dyskinesias in parkinsonian rats

(2010) Katherine E. Soderstrom et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Differential structural plasticity of corticostriatal and thalamostriatal axo-spinous synapses in MPTP-treated parkinsonian monkeys

(2010) Rosa M. Villalba et al.   JOURNAL OF COMPARATIVE NEUROLOGY

A neurocomputational method for fully automated 3D dendritic spine detection and segmentation of medium-sized spiny neurons

(2010) Yong Zhang et al.   NEUROIMAGE

Striatal Spine Plasticity in Parkinson's Disease

(2010) Rosa M. Villalba et al.   Frontiers in Neuroanatomy

Physiology and Pharmacology of Striatal Neurons

(2009) Anatol C. Kreitzer   Annual Review of Neuroscience

Genetic Inactivation of Dopamine D1 but Not D2 Receptors Inhibits L-DOPA–Induced Dyskinesia and Histone Activation

(2009) Sanja Darmopil et al.   BIOLOGICAL PSYCHIATRY

Effect of unilateral lesion of the nigrostriatal dopamine pathway on survival and neurochemistry of parafascicular nucleus neurons in the rat — Evaluation of time-course and LGR8 expression

(2009) Katayoun Sedaghat et al.   BRAIN RESEARCH

Role of glial cells in the formation and maintenance of synapses

(2009) Frank W. Pfrieger   BRAIN RESEARCH REVIEWS

Striatal spine plasticity in Parkinson's disease: pathological or not?

(2009) Y. Smith et al.   PARKINSONISM & RELATED DISORDERS

Thalamic changes in Parkinson's disease

(2009) Glenda M. Halliday   PARKINSONISM & RELATED DISORDERS

Homeostatic Plasticity of Striatal Neurons Intrinsic Excitability following Dopamine Depletion

(2009) Karima Azdad et al.   PLoS One

Counting synapses using FIB/SEM microscopy: a true revolution for ultrastructural volume reconstruction

(2009) Angel Merchan-Pérez   Frontiers in Neuroanatomy

Balancing Structure and Function at Hippocampal Dendritic Spines

(2008) Jennifer N Bourne et al.   Annual Review of Neuroscience

Antagonizing L-type Ca2+ Channel Reduces Development of Abnormal Involuntary Movement in the Rat Model of L-3,4-Dihydroxyphenylalanine-Induced Dyskinesia

(2008) Stefan Schuster et al.   BIOLOGICAL PSYCHIATRY

The thalamostriatal systems: Anatomical and functional organization in normal and parkinsonian states

(2008) Yoland Smith et al.   BRAIN RESEARCH BULLETIN

Dopamine Innervation in the Thalamus: Monkey versus Rat

(2008) M. A. Garcia-Cabezas et al.   CEREBRAL CORTEX

Differential synaptic plasticity of the corticostriatal and thalamostriatal systems in an MPTP-treated monkey model of parkinsonism

(2008) Dinesh V. Raju et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Dopaminergic denervation and spine loss in the striatum of MPTP-treated monkeys

(2008) Rosa M. Villalba et al.   EXPERIMENTAL NEUROLOGY

Differential Excitability and Modulation of Striatal Medium Spiny Neuron Dendrites

(2008) M. Day et al.   JOURNAL OF NEUROSCIENCE

Inversion of Dopamine Responses in Striatal Medium Spiny Neurons and Involuntary Movements

(2008) L. Liang et al.   JOURNAL OF NEUROSCIENCE

A Dopaminergic Axon Lattice in the Striatum and Its Relationship with Cortical and Thalamic Terminals

(2008) J. Moss et al.   JOURNAL OF NEUROSCIENCE

Dichotomous Anatomical Properties of Adult Striatal Medium Spiny Neurons

(2008) T. S. Gertler et al.   JOURNAL OF NEUROSCIENCE

Serial Section Scanning Electron Microscopy of Adult Brain Tissue Using Focused Ion Beam Milling

(2008) G. Knott et al.   JOURNAL OF NEUROSCIENCE

Striatal and extrastriatal dopamine in the basal ganglia: An overview of its anatomical organization in normal and Parkinsonian brains

(2008) Yoland Smith et al.   MOVEMENT DISORDERS

Striatal Plasticity and Basal Ganglia Circuit Function

(2008) Anatol C. Kreitzer et al.   NEURON

The Mystery and Magic of Glia: A Perspective on Their Roles in Health and Disease

(2008) Ben A. Barres   NEURON

Differential astroglial activation in 6-hydroxydopamine models of Parkinson’s disease

(2008) Jeannette Henning et al.   NEUROSCIENCE RESEARCH

Activity-Dependent Structural and Functional Plasticity of Astrocyte-Neuron Interactions

(2008) Dionysia T. Theodosis et al.   PHYSIOLOGICAL REVIEWS

Striatal Proteomic Analysis Suggests that First L-Dopa Dose Equates to Chronic Exposure

(2008) Birger Scholz et al.   PLoS One

Dichotomous Dopaminergic Control of Striatal Synaptic Plasticity

(2008) W. Shen et al.   SCIENCE

The neuroanatomist's dream, the problems and solutions, and the ultimate aim

(2008) Javier DeFelipe   Frontiers in Neuroscience