An unusual conformation from Na+-sensitive non-gastric proton pump mutants reveals molecular mechanisms of cooperative Na+-binding

Structure and function of H+/K+ pump mutants reveal Na+/K+ pump mechanisms

(2022) Victoria C. Young et al.   Nature Communications

Displacement of the Na+/K+ pump’s transmembrane domains demonstrates conserved conformational changes in P-type 2 ATPases

(2021) Victoria C. Young et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cryo-EM of the ATP11C flippase reconstituted in Nanodiscs shows a distended phospholipid bilayer inner membrane around transmembrane helix 2

(2021) Hanayo Nakanishi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Gastric proton pump with two occluded K+ engineered with sodium pump-mimetic mutations

(2021) Kazuhiro Abe et al.   Nature Communications

Transport Cycle of Plasma Membrane Flippase ATP11C by Cryo-EM

(2020) Hanayo Nakanishi et al.   Cell Reports

A single K+-binding site in the crystal structure of the gastric proton pump

(2019) Kenta Yamamoto et al.   eLife

Crystal structures of the gastric proton pump

(2018) Kazuhiro Abe et al.   NATURE

Mechanism of the E2 to E1 transition in Ca2+ pump revealed by crystal structures of gating residue mutants

(2018) Naoki Tsunekawa et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

New tools for automated high-resolution cryo-EM structure determination in RELION-3

(2018) Jasenko Zivanov et al.   eLife

A Bayesian approach to beam-induced motion correction in cryo-EM single-particle analysis

(2018) Jasenko Zivanov et al.   IUCrJ

cryoSPARC: algorithms for rapid unsupervised cryo-EM structure determination

(2017) Ali Punjani et al.   NATURE METHODS

The cryo-EM structure of gastric H+,K+-ATPase with bound BYK99, a high-affinity member of K+-competitive, imidazo[1,2-a]pyridine inhibitors

(2017) Kazuhiro Abe et al.   Scientific Reports

Arginine substitution of a cysteine in transmembrane helix M8 converts Na+,K+-ATPase to an electroneutral pump similar to H+,K+-ATPase

(2016) Rikke Holm et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Airway acidification initiates host defense abnormalities in cystic fibrosis mice

(2016) V. S. Shah et al.   SCIENCE

Electron crystallography of ultrathin 3D protein crystals: Atomic model with charges

(2015) Koji Yonekura et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Crystal structure of a Na+-bound Na+,K+-ATPase preceding the E1P state

(2013) Ryuta Kanai et al.   NATURE

Crystal Structure of Na + , K + -ATPase in the Na + -Bound State

(2013) Maria Nyblom et al.   SCIENCE

Cryo-EM structure of gastric H+,K+-ATPase with a single occupied cation-binding site

(2012) K. Abe et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Selectivity of externally facing ion-binding sites in the Na/K pump to alkali metals and organic cations

(2010) I. M. Ratheal et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural and thermodynamic analysis of the GFP:GFP-nanobody complex

(2010) Marta H. Kubala et al.   PROTEIN SCIENCE

Inter-subunit interaction of gastric H+,K+-ATPase prevents reverse reaction of the transport cycle

(2009) Kazuhiro Abe et al.   EMBO JOURNAL

Formation of the Stable Structural Analog of ADP-sensitive Phosphoenzyme of Ca2+-ATPase with Occluded Ca2+by Beryllium Fluoride

(2009) Stefania Danko et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

BacMam system for high-level expression of recombinant soluble and membrane glycoproteins for structural studies

(2008) Abhiram Dukkipati et al.   PROTEIN EXPRESSION AND PURIFICATION