Airway acidification initiates host defense abnormalities in cystic fibrosis mice

Origins of Cystic Fibrosis Lung Disease

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A Functional Anatomic Defect of the Cystic Fibrosis Airway

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Neonates with cystic fibrosis have a reduced nasal liquid pH; A small pilot study

(2014) Mahmoud H. Abou Alaiwa et al.   Journal of Cystic Fibrosis

pH modulates the activity and synergism of the airway surface liquid antimicrobials β-defensin-3 and LL-37

(2014) Mahmoud H. Abou Alaiwa et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Impaired mucus detachment disrupts mucociliary transport in a piglet model of cystic fibrosis

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Efficient delivery of RNA interference oligonucleotides to polarized airway epithelia in vitro

(2013) Shyam Ramachandran et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Intestinal CFTR expression alleviates meconium ileus in cystic fibrosis pigs

(2013) David A. Stoltz et al.   JOURNAL OF CLINICAL INVESTIGATION

Molecular basis for pH-dependent mucosal dehydration in cystic fibrosis airways

(2013) A. L. Garland et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Principles for Valid Histopathologic Scoring in Research

(2013) K. N. Gibson-Corley et al.   VETERINARY PATHOLOGY

Bicarbonate and functional CFTR channel are required for proper mucin secretion and link cystic fibrosis with its mucus phenotype

(2012) Jenny K. Gustafsson et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Reduced airway surface pH impairs bacterial killing in the porcine cystic fibrosis lung

(2012) Alejandro A. Pezzulo et al.   NATURE

Cystic fibrosis: a mucosal immunodeficiency syndrome

(2012) Taylor Sitarik Cohen et al.   NATURE MEDICINE

Dynamic modulation of ANO1/TMEM16A HCO3- permeability by Ca2+/calmodulin

(2012) J. Jung et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hyperviscous airway periciliary and mucous liquid layers in cystic fibrosis measured by confocal fluorescence photobleaching

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Muscarinic activation of Ca2+-activated Cl−current in interstitial cells of Cajal

(2011) Mei Hong Zhu et al.   JOURNAL OF PHYSIOLOGY-LONDON

Loss of Anion Transport without Increased Sodium Absorption Characterizes Newborn Porcine Cystic Fibrosis Airway Epithelia

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Function of the HVCN1 proton channel in airway epithelia and a naturally occurring mutation, M91T

(2010) David Iovannisci et al.   JOURNAL OF GENERAL PHYSIOLOGY

Cystic Fibrosis Pigs Develop Lung Disease and Exhibit Defective Bacterial Eradication at Birth

(2010) D. A. Stoltz et al.   Science Translational Medicine

The porcine lung as a potential model for cystic fibrosis

(2008) Christopher S. Rogers et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Cystic fibrosis: impaired bicarbonate secretion and mucoviscidosis

(2008) Paul M Quinton   LANCET

Chemical Modification of siRNAs for In Vivo Use

(2008) Mark A. Behlke   OLIGONUCLEOTIDES

Chemical Modification Patterns Compatible with High Potency Dicer-Substrate Small Interfering RNAs

(2008) Michael A. Collingwood et al.   OLIGONUCLEOTIDES

Disruption of the CFTR Gene Produces a Model of Cystic Fibrosis in Newborn Pigs

(2008) C. S. Rogers et al.   SCIENCE

TMEM16A, A Membrane Protein Associated with Calcium-Dependent Chloride Channel Activity

(2008) A. Caputo et al.   SCIENCE