The cryo-EM structure of gastric H+,K+-ATPase with bound BYK99, a high-affinity member of K+-competitive, imidazo[1,2-a]pyridine inhibitors

The binding selectivity of vonoprazan (TAK-438) to the gastric H+,K+-ATPase

(2015) D. R. Scott et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Synthetic studies of five-membered heteroaromatic derivatives as potassium-competitive acid blockers (P-CABs)

(2015) Yasuyoshi Arikawa et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Systematic Comparison of Molecular Conformations of H+,K+-ATPase Reveals an Important Contribution of the A-M2 Linker for the Luminal Gating

(2014) Kazuhiro Abe et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Screening and large-scale expression of membrane proteins in mammalian cells for structural studies

(2014) April Goehring et al.   Nature Protocols

Crystal structure of the high-affinity Na+,K+-ATPase-ouabain complex with Mg2+ bound in the cation binding site

(2013) M. Laursen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Carbon sandwich preparation preserves quality of two-dimensional crystals for cryo-electron microscopy

(2013) Fan Yang et al.   Microscopy

Cryo-EM structure of gastric H+,K+-ATPase with a single occupied cation-binding site

(2012) K. Abe et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Conformational rearrangement of gastric H+,K+-ATPase induced by an acid suppressant

(2011) Kazuhiro Abe et al.   Nature Communications

Inter-subunit interaction of gastric H+,K+-ATPase prevents reverse reaction of the transport cycle

(2009) Kazuhiro Abe et al.   EMBO JOURNAL

The gastric HK-ATPase: structure, function, and inhibition

(2008) Jai Moo Shin et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

BacMam system for high-level expression of recombinant soluble and membrane glycoproteins for structural studies

(2008) Abhiram Dukkipati et al.   PROTEIN EXPRESSION AND PURIFICATION