Role of Uric Acid Metabolism-Related Inflammation in the Pathogenesis of Metabolic Syndrome Components Such as Atherosclerosis and Nonalcoholic Steatohepatitis
Published 2016 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Role of Uric Acid Metabolism-Related Inflammation in the Pathogenesis of Metabolic Syndrome Components Such as Atherosclerosis and Nonalcoholic Steatohepatitis
Authors
Keywords
-
Journal
MEDIATORS OF INFLAMMATION
Volume 2016, Issue -, Pages 1-15
Publisher
Hindawi Limited
Online
2016-12-15
DOI
10.1155/2016/8603164
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Cellular cholesterol accumulation modulates high fat high sucrose (HFHS) diet-induced ER stress and hepatic inflammasome activation in the development of non-alcoholic steatohepatitis
- (2016) Amir Bashiri et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- Uric acid lowering therapy in cardiovascular diseases
- (2016) Maurizio Volterrani et al. INTERNATIONAL JOURNAL OF CARDIOLOGY
- Hyperuricemia and the risk for coronary heart disease morbidity and mortality a systematic review and dose-response meta-analysis
- (2016) Min Li et al. Scientific Reports
- The xanthine oxidase inhibitor febuxostat suppresses development of nonalcoholic steatohepatitis in a rodent model
- (2015) Yusuke Nakatsu et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- Renoprotective effects of febuxostat in hyperuricemic patients with chronic kidney disease: a parallel-group, randomized, controlled trial
- (2015) Kenichi Tanaka et al. Clinical and Experimental Nephrology
- A Mendelian Randomization Study of Circulating Uric Acid and Type 2 Diabetes
- (2015) Ivonne Sluijs et al. DIABETES
- Serum Uric Acid Levels and Risk of Metabolic Syndrome: A Dose-Response Meta-Analysis of Prospective Studies
- (2015) Huiping Yuan et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Xanthine oxidase in non-alcoholic fatty liver disease and hyperuricemia: One stone hits two birds
- (2015) Chengfu Xu et al. JOURNAL OF HEPATOLOGY
- Intracellular ATP Decrease Mediates NLRP3 Inflammasome Activation upon Nigericin and Crystal Stimulation
- (2015) Johji Nomura et al. JOURNAL OF IMMUNOLOGY
- Febuxostat pretreatment attenuates myocardial ischemia/reperfusion injury via mitochondrial apoptosis
- (2015) Shulin Wang et al. Journal of Translational Medicine
- Risk factors for tumor lysis syndrome in childhood acute myeloid leukemia treated with a uniform protocol without rasburicase prophylaxis
- (2015) Kenji Kishimoto et al. LEUKEMIA & LYMPHOMA
- Febuxostat Ameliorates Diabetic Renal Injury in a Streptozotocin-Induced Diabetic Rat Model
- (2014) Hong-Joo Lee et al. AMERICAN JOURNAL OF NEPHROLOGY
- Impact of allopurinol on risk of myocardial infarction
- (2014) L Grimaldi-Bensouda et al. ANNALS OF THE RHEUMATIC DISEASES
- High uric acid directly inhibits insulin signalling and induces insulin resistance
- (2014) Yuzhang Zhu et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- A multiple free-radical scavenging (MULTIS) study on the antioxidant capacity of a neuroprotective drug, edaravone as compared with uric acid, glutathione, and trolox
- (2014) Erisa Kamogawa et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Monosodium urate crystals trigger Nrf2- and heme oxygenase-1-dependent inflammation in THP-1 cells
- (2014) Jhih-Jia Jhang et al. Cellular & Molecular Immunology
- The relationship of serum uric acid with non-alcoholic fatty liver disease
- (2014) Erdim Sertoglu et al. CLINICAL BIOCHEMISTRY
- Uric acid induces endothelial dysfunction by vascular insulin resistance associated with the impairment of nitric oxide synthesis
- (2014) You-Jin Choi et al. FASEB JOURNAL
- Uric acid-dependent inhibition of AMP kinase induces hepatic glucose production in diabetes and starvation: evolutionary implications of the uricase loss in hominids
- (2014) Christina Cicerchi et al. FASEB JOURNAL
- NLRP3 inflammasome activation is required for fibrosis development in NAFLD
- (2014) Alexander Wree et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- Uric acid induces fat accumulation via generation of endoplasmic reticulum stress and SREBP-1c activation in hepatocytes
- (2014) Yea-Jin Choi et al. LABORATORY INVESTIGATION
- Hyperuricemia and Risk of Incident Hypertension: A Systematic Review and Meta-Analysis of Observational Studies
- (2014) Ji Wang et al. PLoS One
- Role of elevated serum uric acid levels at the onset of overt nephropathy in the risk for renal function decline in patients with type 2 diabetes
- (2014) Kentaro Tanaka et al. Journal of Diabetes Investigation
- Xanthine Oxidase Inhibition by Febuxostat Attenuates Experimental Atherosclerosis in Mice
- (2014) Johji Nomura et al. Scientific Reports
- Effect of Plasma Uric Acid on Antioxidant Capacity, Oxidative Stress, and Insulin Sensitivity in Obese Subjects
- (2013) E. Fabbrini et al. DIABETES
- Serum uric acid levels and incidence of impaired fasting glucose and type 2 diabetes mellitus: A meta-analysis of cohort studies
- (2013) Zhaotong Jia et al. DIABETES RESEARCH AND CLINICAL PRACTICE
- Uric Acid Secretion from Adipose Tissue and Its Increase in Obesity
- (2013) Yu Tsushima et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Epidemiology of Hepatocellular Carcinoma
- (2013) Sahil Mittal et al. JOURNAL OF CLINICAL GASTROENTEROLOGY
- Serum uric acid level in patients with relapsing-remitting multiple sclerosis
- (2013) Fereshteh Ashtari et al. JOURNAL OF CLINICAL NEUROSCIENCE
- Xanthine oxidase and the fetal cardiovascular defence to hypoxia in late gestation ovine pregnancy
- (2013) Andrew D. Kane et al. JOURNAL OF PHYSIOLOGY-LONDON
- Superoxide production pathways in aortas of diabetic rats: beneficial effects of insulin therapy and endurance training
- (2013) L. Malardé et al. MOLECULAR AND CELLULAR BIOCHEMISTRY
- The global NAFLD epidemic
- (2013) Rohit Loomba et al. Nature Reviews Gastroenterology & Hepatology
- High Serum Uric Acid and Increased Risk of Type 2 Diabetes: A Systemic Review and Meta-Analysis of Prospective Cohort Studies
- (2013) Qin Lv et al. PLoS One
- Caspase-1 as a Central Regulator of High Fat Diet-Induced Non-Alcoholic Steatohepatitis
- (2013) Laura J. Dixon et al. PLoS One
- Febuxostat, an Inhibitor of Xanthine Oxidase, Suppresses Lipopolysaccharide-Induced MCP-1 Production via MAPK Phosphatase-1-Mediated Inactivation of JNK
- (2013) Johji Nomura et al. PLoS One
- Independent and conjoint associations of gout and hyperuricaemia with total and cardiovascular mortality
- (2013) A.G. Stack et al. QJM-AN INTERNATIONAL JOURNAL OF MEDICINE
- Oxidative stress in vascular disease and its pharmacological prevention
- (2013) Huige Li et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Relation of Uric Acid to Serum Levels of High-Sensitivity C-Reactive Protein, Triglycerides, and High-Density Lipoprotein Cholesterol and to Hepatic Steatosis
- (2012) Tanya Keenan et al. AMERICAN JOURNAL OF CARDIOLOGY
- Febuxostat suppressed renal ischemia–reperfusion injury via reduced oxidative stress
- (2012) Hidetoshi Tsuda et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Autophagy Links Inflammasomes to Atherosclerotic Progression
- (2012) Babak Razani et al. Cell Metabolism
- Use of xanthine oxidase inhibitor febuxostat inhibits renal interstitial inflammation and fibrosis in unilateral ureteral obstructive nephropathy
- (2012) Hiroki Omori et al. Clinical and Experimental Nephrology
- Febuxostat Improves the Local and Remote Organ Changes Induced by Intestinal Ischemia/Reperfusion in Rats
- (2012) Amani Nabil Shafik DIGESTIVE DISEASES AND SCIENCES
- NASH is an Infl ammatory Disorder: Pathogenic, Prognostic and Therapeutic Implications
- (2012) Geoffrey C. Farrell et al. Gut and Liver
- Elovl6 promotes nonalcoholic steatohepatitis
- (2012) Takashi Matsuzaka et al. HEPATOLOGY
- Toll-like receptor 2 and palmitic acid cooperatively contribute to the development of nonalcoholic steatohepatitis through inflammasome activation in mice
- (2012) Kouichi Miura et al. HEPATOLOGY
- Uric Acid Reduction Rectifies Prehypertension in Obese Adolescents
- (2012) Beth Soletsky et al. HYPERTENSION
- Uric Acid Induces Hepatic Steatosis by Generation of Mitochondrial Oxidative Stress
- (2012) Miguel A. Lanaspa et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Effect of Allopurinol on Blood Pressure: A Systematic Review and Meta-Analysis
- (2012) Vikram Agarwal et al. Journal of Clinical Hypertension
- The role of inflammasome-derived IL-1 in driving IL-17 responses
- (2012) Kingston H. G. Mills et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Uric acid levels predict survival in men with amyotrophic lateral sclerosis
- (2012) Sabrina Paganoni et al. JOURNAL OF NEUROLOGY
- A role for xanthine oxidase in the control of fetal cardiovascular function in late gestation sheep
- (2012) E. A. Herrera et al. JOURNAL OF PHYSIOLOGY-LONDON
- Inflammasome-mediated dysbiosis regulates progression of NAFLD and obesity
- (2012) Jorge Henao-Mejia et al. NATURE
- Uric acid as a danger signal in gout and its comorbidities
- (2012) Kenneth L. Rock et al. Nature Reviews Rheumatology
- Serum uric acid levels in patients with multiple sclerosis: a meta-analysis
- (2012) Bo Liu et al. NEUROLOGICAL RESEARCH
- Uric Acid Stimulates Fructokinase and Accelerates Fructose Metabolism in the Development of Fatty Liver
- (2012) Miguel A. Lanaspa et al. PLoS One
- Counteracting Roles of AMP Deaminase and AMP Kinase in the Development of Fatty Liver
- (2012) Miguel A. Lanaspa et al. PLoS One
- Hyperuricemia is associated with histological liver damage in patients with non-alcoholic fatty liver disease
- (2011) S. Petta et al. ALIMENTARY PHARMACOLOGY & THERAPEUTICS
- Xanthine Oxidoreductase Is Involved in Macrophage Foam Cell Formation and Atherosclerosis Development
- (2011) Akifumi Kushiyama et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Risk of macrovascular disease stratified by stage of chronic kidney disease in type 2 diabetic patients: critical level of the estimated glomerular filtration rate and the significance of hyperuricemia
- (2011) Kentaro Tanaka et al. Clinical and Experimental Nephrology
- Hyperuricemia as a Mediator of the Proinflammatory Endocrine Imbalance in the Adipose Tissue in a Murine Model of the Metabolic Syndrome
- (2011) W. Baldwin et al. DIABETES
- No evidence for a causal link between uric acid and type 2 diabetes: a Mendelian randomisation approach
- (2011) R. Pfister et al. DIABETOLOGIA
- Predictors of Nonalcoholic Steatohepatitis in Obese Children
- (2011) Stacee Marie Lerret et al. Gastroenterology Nursing
- Fatty acid and endotoxin activate inflammasomes in mouse hepatocytes that release danger signals to stimulate immune cells
- (2011) Timea Csak et al. HEPATOLOGY
- Systemic Oxidative Stress and Endothelial Dysfunction is Associated With an Attenuated Acute Vascular Response to Inhaled Prostanoid in Pulmonary Artery Hypertension Patients
- (2011) Luigi A. Gabrielli et al. JOURNAL OF CARDIAC FAILURE
- Uric and 1-Methyluric Acids: Metabolic Wastes or Antiradical Protectors?
- (2011) Jorge Rafael León-Carmona et al. JOURNAL OF PHYSICAL CHEMISTRY B
- Mechanistic Insights Into the Therapeutic Use of High-Dose Allopurinol in Angina Pectoris
- (2011) Narasimharajapura S. Rajendra et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Xanthine Oxidase-Derived ROS Upregulate Egr-1 via ERK1/2 in PA Smooth Muscle Cells; Model to Test Impact of Extracellular ROS in Chronic Hypoxia
- (2011) Tanya Hartney et al. PLoS One
- Investigation of the Oxidative Effect of Chronic Hyperammonemia on the Kidney and the Possible Protective Effect of Allopurinol
- (2011) Onur Elmas et al. RENAL FAILURE
- Serum Uric Acid Levels and the Risk of Type 2 Diabetes: A Prospective Study
- (2010) Vidula Bhole et al. AMERICAN JOURNAL OF MEDICINE
- The Inflammasomes
- (2010) Kate Schroder et al. CELL
- Involvement of xanthine oxidase and hypoxia-inducible factor 1 in Toll-like receptor 7/8-mediated activation of caspase 1 and interleukin-1β
- (2010) Sally A. Nicholas et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Serum Uric Acid as a Predictor for the Development of Nonalcoholic Fatty Liver Disease in Apparently Healthy Subjects: A 5-Year Retrospective Cohort Study
- (2010) Jae Woong Lee et al. Gut and Liver
- Dietary inhibition of xanthine oxidase attenuates radiation-induced endothelial dysfunction in rat aorta
- (2010) Kevin G. Soucy et al. JOURNAL OF APPLIED PHYSIOLOGY
- Xanthine Oxidoreductase Promotes the Inflammatory State of Mononuclear Phagocytes through Effects on Chemokine Expression, Peroxisome Proliferator-activated Receptor-γ Sumoylation, and HIF-1α
- (2010) Sophie Gibbings et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Allopurinol and xanthine oxidase inhibition in liver ischemia reperfusion
- (2010) Stephanie Peglow et al. Journal of Hepato-Biliary-Pancreatic Sciences
- Effect of high-dose allopurinol on exercise in patients with chronic stable angina: a randomised, placebo controlled crossover trial
- (2010) Awsan Noman et al. LANCET
- NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals
- (2010) Peter Duewell et al. NATURE
- The role of fructose in the pathogenesis of NAFLD and the metabolic syndrome
- (2010) Jung Sub Lim et al. Nature Reviews Gastroenterology & Hepatology
- Nitric oxide and oxidative stress in vascular disease
- (2010) Ulrich Förstermann PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY
- The NLRP3 Inflammasome: A Sensor for Metabolic Danger?
- (2010) K. Schroder et al. SCIENCE
- Exaggerated liver injury induced by renal ischemia reperfusion in diabetes: Effect of exenatide
- (2010) JitendraD Vaghasiya et al. Saudi Journal of Gastroenterology
- Uric Acid Is a Danger Signal Activating NALP3 Inflammasome in Lung Injury Inflammation and Fibrosis
- (2009) Pamela Gasse et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Uric Acid and Insulin Sensitivity and Risk of Incident Hypertension
- (2009) John P. Forman et al. ARCHIVES OF INTERNAL MEDICINE
- Xanthine oxidase is one of the major sources of superoxide anion radicals in blood after reperfusion in rats with forebrain ischemia/reperfusion
- (2009) Takeru Ono et al. BRAIN RESEARCH
- Uric Acid-Lowering Treatment With Benzbromarone in Patients With Heart Failure
- (2009) Kazuhide Ogino et al. Circulation-Heart Failure
- Association Between Serum Uric Acid and Development of Type 2 Diabetes
- (2009) S. Kodama et al. DIABETES CARE
- Xanthine Oxidoreductase Depletion Induces Renal Interstitial Fibrosis Through Aberrant Lipid and Purine Accumulation in Renal Tubules
- (2009) Toshio Ohtsubo et al. HYPERTENSION
- Excessive fructose intake induces the features of metabolic syndrome in healthy adult men: role of uric acid in the hypertensive response
- (2009) S E Perez-Pozo et al. INTERNATIONAL JOURNAL OF OBESITY
- Exposure of human keratinocytes to ischemia, hyperglycemia and their combination induces oxidative stress via the enzymes inducible nitric oxide synthase and xanthine oxidase
- (2009) Meital Portugal-Cohen et al. JOURNAL OF DERMATOLOGICAL SCIENCE
- Association of serum uric acid level with non-alcoholic fatty liver disease: A cross-sectional study
- (2009) Youming Li et al. JOURNAL OF HEPATOLOGY
- Uric acid stimulates vascular smooth muscle cell proliferation and oxidative stress via the vascular renin–angiotensin system
- (2009) Dalila B Corry et al. JOURNAL OF HYPERTENSION
- Low uric acid levels in serum of patients with ALS: Further evidence for oxidative stress?
- (2009) D. Keizman et al. JOURNAL OF THE NEUROLOGICAL SCIENCES
- Thioredoxin-interacting protein links oxidative stress to inflammasome activation
- (2009) Rongbin Zhou et al. NATURE IMMUNOLOGY
- Effects of Allopurinol on Ischemia and Reperfusion in Rabbit Livers
- (2009) M.O. Taha et al. TRANSPLANTATION PROCEEDINGS
- Parameters of nitrogen metabolism during insulin hypoglycemia in rats with alloxan-induced diabetes
- (2008) N. B. Medvedeva et al. BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE
- Effect of Allopurinol on Blood Pressure of Adolescents With Newly Diagnosed Essential Hypertension
- (2008) Daniel I. Feig et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Role of Xanthine Oxidase Activation and Reduced Glutathione Depletion in Rhinovirus Induction of Inflammation in Respiratory Epithelial Cells
- (2008) Alberto Papi et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Origin and physiological roles of inflammation
- (2008) Ruslan Medzhitov NATURE
- Effect of Febuxostat on the Progression of Renal Disease in 5/6 Nephrectomy Rats with and without Hyperuricemia
- (2008) Laura G. Sánchez-Lozada et al. NEPHRON PHYSIOLOGY
- Uric Acid and Cardiovascular Risk
- (2008) Daniel I. Feig et al. NEW ENGLAND JOURNAL OF MEDICINE
- Inactivation of Nitric Oxide by Uric Acid
- (2008) Christine Gersch et al. NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS
- Contribution of xanthine oxidase-derived superoxide to chronic hypoxic pulmonary hypertension in neonatal rats
- (2007) Robert P. Jankov et al. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
- Production, detection, and adaptive responses to free radicals in exercise
- (2007) Sean Sachdev et al. FREE RADICAL BIOLOGY AND MEDICINE
Create your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create NowAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started