Hepatic Transcriptome and Its Regulation Following Soluble Epoxide Hydrolase Inhibition in Alcohol-Associated Liver Disease

Endoplasmic reticulum stress in liver diseases

(2022) Amir Ajoolabady et al.   HEPATOLOGY

Neutral ceramidase-dependent regulation of macrophage metabolism directs intestinal immune homeostasis and controls enteric infection

(2022) Rui Sun et al.   Cell Reports

The epoxy fatty acid pathway enhances cAMP in mammalian cells through multiple mechanisms

(2022) Naoki Matsumoto et al.   PROSTAGLANDINS & OTHER LIPID MEDIATORS

Macrophages play a key role in tissue repair and regeneration

(2022) Yajie Yu et al.   PeerJ

Ethanol and its Nonoxidative Metabolites Promote Acute Liver Injury by Inducing ER Stress, Adipocyte Death and Lipolysis

(2022) Seol Hee Park et al.   Cellular and Molecular Gastroenterology and Hepatology

Soluble epoxide hydrolase inhibition enhances production of specialized pro‐resolving lipid mediator and promotes macrophage plasticity

(2022) Henrique B. Abdalla et al.   BRITISH JOURNAL OF PHARMACOLOGY

Metabolic Analysis of Nucleosides/Bases in the Urine and Serum of Patients with Alcohol-Associated Liver Disease

(2022) Liqing He et al.   Metabolites

Beneficial effects of an endogenous enrichment in n3‐PUFAs on Wnt signaling are associated with attenuation of alcohol‐mediated liver disease in mice

(2021) Dennis R. Warner et al.   FASEB JOURNAL

Deciphering Epitranscriptome: Modification of mRNA Bases Provides a New Perspective for Post-transcriptional Regulation of Gene Expression

(2021) Suresh Kumar et al.   Frontiers in Cell and Developmental Biology

Gender differences in diet-induced steatotic disease in Cyp2b-null mice

(2020) Melissa M. Heintz et al.   PLoS One

Extracellular SQSTM1 mediates bacterial septic death in mice through insulin receptor signalling

(2020) Borong Zhou et al.   Nature Microbiology

Soluble epoxide hydrolase hepatic deficiency ameliorates alcohol-associated liver disease

(2020) Aline Mello et al.   Cellular and Molecular Gastroenterology and Hepatology

Programmed cell death in alcohol-associated liver disease

(2020) Tatsunori Miyata et al.   Clinical and Molecular Hepatology

Simultaneous Quantification of Nucleosides and Nucleotides from Biological Samples

(2019) Liqing He et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Alcoholic Hepatitis: A Review

(2019) Nooshin Hosseini et al.   ALCOHOL AND ALCOHOLISM

Profiling of Polar Metabolites in Mouse Feces Using Four Analytical Platforms to Study the Effects Of Cathelicidin-Related Antimicrobial Peptide in Alcoholic Liver Disease

(2019) Liqing He et al.   JOURNAL OF PROTEOME RESEARCH

1-Trifluoromethoxyphenyl-3-(1-propionylpiperidin-4-yl) Urea, a Selective and Potent Dual Inhibitor of Soluble Epoxide Hydrolase and p38 Kinase Intervenes in Alzheimer’s Signaling in Human Nerve Cells

(2019) Zhibin Liang et al.   ACS Chemical Neuroscience

Role of identified RNA N6-methyladenosine methylation in liver

(2019) Kechen Xu et al.   ANALYTICAL BIOCHEMISTRY

Mortality and Costs Associated with Alcoholic Hepatitis: A Claims Analysis of a Commercially Insured Population

(2018) Julie A. Thompson et al.   ALCOHOL

Identification and optimization of soluble epoxide hydrolase inhibitors with dual potency towards fatty acid amide hydrolase

(2018) Sean D. Kodani et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

RNA N6-methyladenosine methyltransferase-like 3 promotes liver cancer progression through YTHDF2-dependent posttranscriptional silencing of SOCS2

(2018) Mengnuo Chen et al.   HEPATOLOGY

Hedgehog signalling in liver pathophysiology

(2018) Mariana Verdelho Machado et al.   JOURNAL OF HEPATOLOGY

Soluble epoxide hydrolase inhibition with t-TUCB alleviates liver fibrosis and portal pressure in carbon tetrachloride-induced cirrhosis in rats

(2018) Chi-Hao Zhang et al.   Clinics and Research in Hepatology and Gastroenterology

Alcoholic liver disease

(2018) Helmut K. Seitz et al.   Nature Reviews Disease Primers

Inhibition of soluble epoxide hydrolase lowers portal hypertension in cirrhotic rats by ameliorating endothelial dysfunction and liver fibrosis

(2017) Wensheng Deng et al.   PROSTAGLANDINS & OTHER LIPID MEDIATORS

Treatment of Severe Alcoholic Hepatitis

(2016) Mark Thursz et al.   GASTROENTEROLOGY

Altered Distribution of Peripheral Blood Maturation-Associated B-Cell Subsets in Chronic Alcoholism

(2015) Julia Almeida et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Transient Receptor Potential Vanilloid 1 Gene Deficiency Ameliorates Hepatic Injury in a Mouse Model of Chronic Binge Alcohol-Induced Alcoholic Liver Disease

(2015) Huilin Liu et al.   AMERICAN JOURNAL OF PATHOLOGY

M2 Macrophage Polarization Mediates Anti-inflammatory Effects of Endothelial Nitric Oxide Signaling

(2015) Woo Je Lee et al.   DIABETES

Structure and Thermodynamics of N6-Methyladenosine in RNA: A Spring-Loaded Base Modification

(2015) Caroline Roost et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

TOX2 regulates human natural killer cell development by controlling T-BET expression

(2014) Q. P. Vong et al.   BLOOD

Serum amyloid P: a systemic regulator of the innate immune response

(2014) Nehemiah Cox et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Inhibition of soluble epoxide hydrolase modulates inflammation and autophagy in obese adipose tissue and liver: Role for omega-3 epoxides

(2014) Cristina López-Vicario et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Role of mitochondria in alcoholic liver disease

(2014) Fatiha Nassir   WORLD JOURNAL OF GASTROENTEROLOGY

M2 Kupffer cells promote M1 Kupffer cell apoptosis: A protective mechanism against alcoholic and nonalcoholic fatty liver disease

(2013) Jinghong Wan et al.   HEPATOLOGY

Chronic plus binge ethanol feeding synergistically induces neutrophil infiltration and liver injury in mice: A critical role for E-selectin

(2013) Adeline Bertola et al.   HEPATOLOGY

Soluble Epoxide Hydrolase Deficiency or Inhibition Attenuates Diet-induced Endoplasmic Reticulum Stress in Liver and Adipose Tissue

(2013) Ahmed Bettaieb et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mouse model of chronic and binge ethanol feeding (the NIAAA model)

(2013) Adeline Bertola et al.   Nature Protocols

Cytochrome P4502S1: a novel monocyte/macrophage fatty acid epoxygenase in human atherosclerotic plaques

(2012) Timo Frömel et al.   BASIC RESEARCH IN CARDIOLOGY

Cyclin D1 inhibits hepatic lipogenesis via repression of carbohydrate response element binding protein and hepatocyte nuclear factor 4α

(2012) Eric A. Hanse et al.   CELL CYCLE

Natural killer cells in liver disease

(2012) Zhigang Tian et al.   HEPATOLOGY

Deficit of tRNALys modification by Cdkal1 causes the development of type 2 diabetes in mice

(2011) Fan-Yan Wei et al.   JOURNAL OF CLINICAL INVESTIGATION

GRAMD4 mimics p53 and mediates the apoptotic function of p73 at mitochondria

(2010) K John et al.   CELL DEATH AND DIFFERENTIATION

Identification of Eukaryotic and Prokaryotic Methylthiotransferase for Biosynthesis of 2-Methylthio-N6-threonylcarbamoyladenosine in tRNA

(2010) Simon Arragain et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Integrated hepatic transcriptome and proteome analysis of mice with high-fat diet-induced nonalcoholic fatty liver disease

(2010) Irina A. Kirpich et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

The Epoxygenases CYP2J2 Activates the Nuclear Receptor PPARα In Vitro and In Vivo

(2009) Jessica A. Wray et al.   PLoS One

Arachidonic acid cytochrome P450 epoxygenase pathway

(2008) Arthur A. Spector   JOURNAL OF LIPID RESEARCH