Deficit of tRNALys modification by Cdkal1 causes the development of type 2 diabetes in mice

The binary switch between life and death of endoplasmic reticulum-stressed β cells

(2011) Christine M Oslowski et al.   Current Opinion in Endocrinology Diabetes and Obesity

Association of a Cyclin-Dependent Kinase 5 Regulatory Subunit-Associated Protein 1-Like 1 (CDKAL1) Polymorphism With Elevated Hemoglobin A1c Levels and the Prevalence of Metabolic Syndrome in Japanese Men: Interaction With Dietary Energy Intake

(2010) K. Miyaki et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

CDKAL1 and type 2 diabetes: a global meta-analysis

(2010) M.A.S. Dehwah et al.   GENETICS AND MOLECULAR RESEARCH

Identification of Eukaryotic and Prokaryotic Methylthiotransferase for Biosynthesis of 2-Methylthio-N6-threonylcarbamoyladenosine in tRNA

(2010) Simon Arragain et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Agmatine-conjugated cytidine in a tRNA anticodon is essential for AUA decoding in archaea

(2010) Yoshiho Ikeuchi et al.   Nature Chemical Biology

Structural aspects of messenger RNA reading frame maintenance by the ribosome

(2010) Lasse B Jenner et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Deletion of CDKAL1 Affects Mitochondrial ATP Generation and First-Phase Insulin Exocytosis

(2010) Mica Ohara-Imaizumi et al.   PLoS One

A comprehensive analysis of translational missense errors in the yeast Saccharomyces cerevisiae

(2010) E. B. Kramer et al.   RNA

ER Stress in Pancreatic   Cells: The Thin Red Line Between Adaptation and Failure

(2010) D. L. Eizirik et al.   Science Signaling

IRE1α Kinase Activation Modes Control Alternate Endoribonuclease Outputs to Determine Divergent Cell Fates

(2009) Dan Han et al.   CELL

Translation Attenuation through eIF2α Phosphorylation Prevents Oxidative Stress and Maintains the Differentiated State in β Cells

(2009) Sung Hoon Back et al.   Cell Metabolism

Association of 18 Confirmed Susceptibility Loci for Type 2 Diabetes With Indices of Insulin Release, Proinsulin Conversion, and Insulin Sensitivity in 5,327 Nondiabetic Finnish Men

(2009) A. Stancakova et al.   DIABETES

The risk allele load accelerates the age-dependent decline in beta cell function

(2009) A. Haupt et al.   DIABETOLOGIA

Fine-tuning of the ribosomal decoding center by conserved methyl-modifications in the Escherichia coli 16S rRNA

(2009) Satoshi Kimura et al.   NUCLEIC ACIDS RESEARCH

Pdx1 (MODY4) regulates pancreatic beta cell susceptibility to ER stress

(2009) Mira M. Sachdeva et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Association between insulin secretion, insulin sensitivity and type 2 diabetes susceptibility variants identified in genome-wide association studies

(2008) Stephanie-May Ruchat et al.   ACTA DIABETOLOGICA

Polymorphisms in the TCF7L2, CDKAL1 and SLC30A8 genes are associated with impaired proinsulin conversion

(2008) K. Kirchhoff et al.   DIABETOLOGIA

Variants of CDKAL1 and IGF2BP2 affect first-phase insulin secretion during hyperglycaemic clamps

(2008) M. J. Groenewoud et al.   DIABETOLOGIA

The Unfolded Protein Response: A Pathway That Links Insulin Demand with β-Cell Failure and Diabetes

(2008) Donalyn Scheuner et al.   ENDOCRINE REVIEWS

CaM kinase Iα–induced phosphorylation of Drp1 regulates mitochondrial morphology

(2008) Xiao-Jian Han et al.   JOURNAL OF CELL BIOLOGY