Copper‐Bacteriochlorin Nanosheet as a Specific Pyroptosis Inducer for Robust Tumor Immunotherapy

Bioactive inorganic nanomaterials for cancer theranostics

(2023) Zifan Pei et al.   CHEMICAL SOCIETY REVIEWS

Open‐shell Nanosensitizers for Glutathione Responsive Cancer Sonodynamic Therapy

(2022) Han Wang et al.   ADVANCED MATERIALS

Metal-based anticancer agents as immunogenic cell death inducers: the past, present, and future

(2022) Sajal Sen et al.   CHEMICAL SOCIETY REVIEWS

A pyroptosis nanotuner for cancer therapy

(2022) Binlong Chen et al.   Nature Nanotechnology

Antioxidant Effect of Tyr-Ala Extracted from Zein on INS-1 Cells and Type 2 Diabetes High-Fat-Diet-Induced Mice

(2022) Jinghui Zhai et al.   Antioxidants

Photocatalytic Superoxide Radical Generator that Induces Pyroptosis in Cancer Cells

(2022) Le Yu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Copper-Catalyzed Glutathione Oxidation is Accelerated by the Anticancer Thiosemicarbazone Dp44mT and Further Boosted at Lower pH

(2022) Enrico Falcone et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Ferritin‐hijacking Nanoparticles Spatiotemporally Directing Endogenous Ferroptosis for Synergistic Anticancer Therapy

(2022) Luwen Zhu et al.   ADVANCED MATERIALS

Specific disruption of glutathione-defense system with activatable single molecule-assembled nanoprodrug for boosted photodynamic/chemotherapy eradication of drug-resistant tumors

(2022) Qin Zeng et al.   BIOMATERIALS

Ultrasound‐Amplified Enzyodynamic Tumor Therapy by Perovskite Nanoenzyme‐Enabled Cell Pyroptosis and Cascade Catalysis

(2022) Meiqi Chang et al.   ADVANCED MATERIALS

Pore-forming proteins as drivers of membrane permeabilization in cell death pathways

(2022) Peter Vandenabeele et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Activation of Pyroptosis by Membrane‐Anchoring AIE Photosensitizer Design: New Prospect for Photodynamic Cancer Cell Ablation

(2021) Min Wu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Channelling inflammation: gasdermins in physiology and disease

(2021) Xing Liu et al.   NATURE REVIEWS DRUG DISCOVERY

Engineering Multienzyme‐Mimicking Covalent Organic Frameworks as Pyroptosis Inducers for Boosting Antitumor Immunity

(2021) Liang Zhang et al.   ADVANCED MATERIALS

Achieving Efficient NIR‐II Type‐I Photosensitizers for Photodynamic/Photothermal Therapy upon Regulating Chalcogen Elements

(2021) Kaikai Wen et al.   ADVANCED MATERIALS

A Carbonic Anhydrase IX (CAIX)‐Anchored Rhenium(I) Photosensitizer Evokes Pyroptosis for Enhanced Anti‐Tumor Immunity

(2021) Xuxian Su et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Biodegradable Upconversion Nanoparticles Induce Pyroptosis for Cancer Immunotherapy

(2021) Binbin Ding et al.   NANO LETTERS

Microenvironment‐Responsive Prodrug‐Induced Pyroptosis Boosts Cancer Immunotherapy

(2021) Yao Xiao et al.   Advanced Science

The glutathione/metallothionein system challenges the design of efficient O2-activating Cu-complexes

(2020) Alice Santoro et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Metal–Organic Framework Nanoparticles Induce Pyroptosis in Cells Controlled by the Extracellular pH

(2020) Evelyn Ploetz et al.   ADVANCED MATERIALS

Mechanism and regulation of pyroptosis-mediated in cancer cell death

(2020) Jianwei Ruan et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Nanoscale Metal–Organic Frameworks Stabilize Bacteriochlorins for Type I and Type II Photodynamic Therapy

(2020) Taokun Luo et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Bacteriochlorins and their metal complexes as NIR-absorbing photosensitizers: properties, mechanisms, and applications

(2020) Barbara Pucelik et al.   COORDINATION CHEMISTRY REVIEWS

Surface-Charge-Switchable Nanoclusters for Magnetic Resonance Imaging-Guided and Glutathione Depletion-Enhanced Photodynamic Therapy

(2020) Jianzhi Zhu et al.   ACS Nano

An NIR‐II‐Emissive Photosensitizer for Hypoxia‐Tolerant Photodynamic Theranostics

(2020) Lanqing Li et al.   ADVANCED MATERIALS

Na2S2O8 Nanoparticles Trigger Antitumor Immunotherapy through Reactive Oxygen Species Storm and Surge of Tumor Osmolarity

(2020) Yang Liu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Intracellular Catalysis with Selected Metal Complexes and Metallic Nanoparticles: Advances toward the Development of Catalytic Metallodrugs

(2019) Joan Josep Soldevila-Barreda et al.   CHEMICAL REVIEWS

A Mn(III)-Sealed Metal-Organic Framework Nanosystem for Redox-Unlocked Tumor Theranostics

(2019) Shuang-Shuang Wan et al.   ACS Nano

The Coming Decade of Cell Death Research: Five Riddles

(2019) Douglas R. Green   CELL

A Bacteriochlorin‐Based Metal–Organic Framework Nanosheet Superoxide Radical Generator for Photoacoustic Imaging‐Guided Highly Efficient Photodynamic Therapy

(2019) Kai Zhang et al.   Advanced Science

Massively Evoking Immunogenic Cell Death by Focused Mitochondrial Oxidative Stress using an AIE Luminogen with a Twisted Molecular Structure

(2019) Chao Chen et al.   ADVANCED MATERIALS

Near-Infrared Light-Initiated Molecular Superoxide Radical Generator: Rejuvenating Photodynamic Therapy against Hypoxic Tumors

(2018) Mingle Li et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

ESCRT-dependent membrane repair negatively regulates pyroptosis downstream of GSDMD activation

(2018) Sebastian Rühl et al.   SCIENCE

Chemotherapy drugs induce pyroptosis through caspase-3 cleavage of a gasdermin

(2017) Yupeng Wang et al.   NATURE

Bioinspired Design of Ultrathin 2D Bimetallic Metal-Organic-Framework Nanosheets Used as Biomimetic Enzymes

(2016) Yixian Wang et al.   ADVANCED MATERIALS

Copper(II)-Graphitic Carbon Nitride Triggered Synergy: Improved ROS Generation and Reduced Glutathione Levels for Enhanced Photodynamic Therapy

(2016) Enguo Ju et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Pyroptosis is driven by non-selective gasdermin-D pore and its morphology is different from MLKL channel-mediated necroptosis

(2016) Xin Chen et al.   CELL RESEARCH

Chlorin-Based Nanoscale Metal–Organic Framework Systemically Rejects Colorectal Cancers via Synergistic Photodynamic Therapy and Checkpoint Blockade Immunotherapy

(2016) Kuangda Lu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Mechanism of hard-nanomaterial clearance by the liver

(2016) Kim M. Tsoi et al.   NATURE MATERIALS

Ultrathin 2D Metal-Organic Framework Nanosheets

(2015) Meiting Zhao et al.   ADVANCED MATERIALS

Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death

(2015) Jianjin Shi et al.   NATURE

Principles of nanoparticle design for overcoming biological barriers to drug delivery

(2015) Elvin Blanco et al.   NATURE BIOTECHNOLOGY

Facile “Modular Assembly” for Fast Construction of a Highly Oriented Crystalline MOF Nanofilm

(2012) Gang Xu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Stable synthetic bacteriochlorins overcome the resistance of melanoma to photodynamic therapy

(2010) Pawel Mroz et al.   FASEB JOURNAL

Surface nano-architecture of a metal–organic framework

(2010) Rie Makiura et al.   NATURE MATERIALS

Cu(I)–Glutathione complex: A potential source of superoxide radicals generation

(2008) Hernán Speisky et al.   BIOORGANIC & MEDICINAL CHEMISTRY