Metal–Organic Framework Nanoparticles Induce Pyroptosis in Cells Controlled by the Extracellular pH

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Activation of Pyroptotic Cell Death Pathways in Cancer: An Alternative Therapeutic Approach

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Multifunctional Efficiency: Extending the Concept of Atom Economy to Functional Nanomaterials

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Quantifying the Ligand-Coated Nanoparticle Delivery to Cancer Cells in Solid Tumours

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Nanoparticles of Metal-Organic Frameworks: On the Road to In Vivo Efficacy in Biomedicine

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Metal-Organic Framework Nanoparticles

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Therapeutic Nanoreactors as In Vivo Nanoplatforms for Cancer Therapy

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The Mitochondrial Apoptotic Effectors BAX/BAK Activate Caspase-3 and -7 to Trigger NLRP3 Inflammasome and Caspase-8 Driven IL-1β Activation

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Betaine Inhibits Interleukin-1β Production and Release: Potential Mechanisms

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Application of zirconium MOFs in drug delivery and biomedicine

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Multifunctional Nanoparticles by Coordinative Self-Assembly of His-Tagged Units with Metal–Organic Frameworks

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Multivariate Metal–Organic Frameworks for Dialing-in the Binding and Programming the Release of Drug Molecules

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Chemotherapy drugs induce pyroptosis through caspase-3 cleavage of a gasdermin

(2017) Yupeng Wang et al.   NATURE

Pyroptosis: Gasdermin-Mediated Programmed Necrotic Cell Death

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Liposome-Coated Iron Fumarate Metal-Organic Framework Nanoparticles for Combination Therapy

(2017) Bernhard Illes et al.   Nanomaterials

On the Mechanism of Cytoprotection by Ferrostatin-1 and Liproxstatin-1 and the Role of Lipid Peroxidation in Ferroptotic Cell Death

(2017) Omkar Zilka et al.   ACS Central Science

Selective Surface PEGylation of UiO-66 Nanoparticles for Enhanced Stability, Cell Uptake, and pH-Responsive Drug Delivery

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Imparting Functionality to MOF Nanoparticles by External Surface Selective Covalent Attachment of Polymers

(2016) Andreas Zimpel et al.   CHEMISTRY OF MATERIALS

Ultrasmall nanoparticles induce ferroptosis in nutrient-deprived cancer cells and suppress tumour growth

(2016) Sung Eun Kim et al.   Nature Nanotechnology

Iron oxide nanoparticles inhibit tumour growth by inducing pro-inflammatory macrophage polarization in tumour tissues

(2016) Saeid Zanganeh et al.   Nature Nanotechnology

Endocytosis Mechanism of Nano Metal-Organic Frameworks for Drug Delivery

(2016) Claudia Orellana-Tavra et al.   Advanced Healthcare Materials

Validating Metal-Organic Framework Nanoparticles for Their Nanosafety in Diverse Biomedical Applications

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Metal–organic framework tethering PNIPAM for ON–OFF controlled release in solution

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MOF nanoparticles coated by lipid bilayers and their uptake by cancer cells

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Extracorporeal Photopheresis Promotes IL-1β Production

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Predicting therapeutic nanomedicine efficacy using a companion magnetic resonance imaging nanoparticle

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Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice

(2014) Jose Pedro Friedmann Angeli et al.   NATURE CELL BIOLOGY

ABT-199, a potent and selective BCL-2 inhibitor, achieves antitumor activity while sparing platelets

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The Chemistry and Applications of Metal-Organic Frameworks

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Biological activity of synthetic ionophores: ion transporters as prospective drugs?

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Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death

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Direct and selective small-molecule activation of proapoptotic BAX

(2012) Evripidis Gavathiotis et al.   Nature Chemical Biology

Iron Homeostasis and the Inflammatory Response

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Electrostatically Mediated Liposome Fusion and Lipid Exchange with a Nanoparticle-Supported Bilayer for Control of Surface Charge, Drug Containment, and Delivery

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Porous metal–organic-framework nanoscale carriers as a potential platform for drug delivery and imaging

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